HUP0302622A2 - Ellenőrzött hatóanyag-leadású, biológiailag lebontható mikrorészecskék, amelyek csökkentett molekulatömegű, tisztított amilopektinalapú keményítőt tartalmaznak - Google Patents
Ellenőrzött hatóanyag-leadású, biológiailag lebontható mikrorészecskék, amelyek csökkentett molekulatömegű, tisztított amilopektinalapú keményítőt tartalmaznakInfo
- Publication number
- HUP0302622A2 HUP0302622A2 HU0302622A HUP0302622A HUP0302622A2 HU P0302622 A2 HUP0302622 A2 HU P0302622A2 HU 0302622 A HU0302622 A HU 0302622A HU P0302622 A HUP0302622 A HU P0302622A HU P0302622 A2 HUP0302622 A2 HU P0302622A2
- Authority
- HU
- Hungary
- Prior art keywords
- starch
- molecular weight
- reduced molecular
- controlled release
- microparticles
- Prior art date
Links
- 229920002472 Starch Polymers 0.000 title abstract 6
- 235000019698 starch Nutrition 0.000 title abstract 6
- 239000008107 starch Substances 0.000 title abstract 6
- 239000011859 microparticle Substances 0.000 title abstract 3
- 229920000945 Amylopectin Polymers 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229940088623 biologically active substance Drugs 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
- B01J13/22—Coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Eljárás parenterálisan beadható mikrorészecskék előállítására, olymódon, hogy csökkentett molekulatömegű, tisztított amilopektin-alapúkeményítőből legalább 20 tömeg%-os vizes oldatot készítenek, azoldatot biológiailag aktív anyaggal elegyítik, keményítőcseppekemulziója képződik egy külső fázist alkotó polimeroldatban, akeményítőcseppeket gélesítik és a gélesedett keményítő részecskéketmegszárítják. A részecskékre adott esetben hatóanyag-leadást szabályzóhéjat visznek föl. A találmány a mikrorészecskékre is vonatkozik,melyek lényegében a kérdéses keményítőből állnak, aminosav tartalmukkevesebb, mint 50 mg és híjával vannak a kovalens kémiaikeresztkötéseknek. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0003615A SE517421C2 (sv) | 2000-10-06 | 2000-10-06 | Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav |
US26045501P | 2001-01-08 | 2001-01-08 | |
PCT/SE2001/002164 WO2002028370A1 (en) | 2000-10-06 | 2001-10-05 | Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0302622A2 true HUP0302622A2 (hu) | 2003-11-28 |
HUP0302622A3 HUP0302622A3 (en) | 2006-07-28 |
Family
ID=26655255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302622A HUP0302622A3 (en) | 2000-10-06 | 2001-10-05 | Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight |
Country Status (10)
Country | Link |
---|---|
US (1) | US20020098203A1 (hu) |
EP (2) | EP1322290A1 (hu) |
JP (2) | JP2004510723A (hu) |
KR (1) | KR20030051687A (hu) |
CN (1) | CN100352427C (hu) |
AU (3) | AU2001294458B2 (hu) |
CA (2) | CA2424892A1 (hu) |
HK (1) | HK1061981A1 (hu) |
HU (1) | HUP0302622A3 (hu) |
WO (2) | WO2002028371A1 (hu) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2844514B1 (fr) * | 2002-09-16 | 2007-10-19 | Neovacs | Produit immunogene stable comprenant des heterocomplexes antigeniques, compositions les contenant et procede de preparation |
US20070218139A1 (en) | 2002-12-20 | 2007-09-20 | Smith Thomas J | High Pressure Compaction For Pharmaceutical Formulations |
US7060299B2 (en) | 2002-12-31 | 2006-06-13 | Battelle Memorial Institute | Biodegradable microparticles that stabilize and control the release of proteins |
GB2398497A (en) * | 2003-02-19 | 2004-08-25 | Walcom Animal Science | Composition for improving immunity of animals |
CA2566075A1 (en) * | 2004-05-12 | 2005-12-01 | Baxter Healthcare S.A. | Microspheres comprising protein and showing injectability at high concentrations of said agent |
US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
GB0423681D0 (en) * | 2004-10-26 | 2004-11-24 | Sec Dep For Environment Food & | Vaccine and nucleic acids |
US20060269576A1 (en) * | 2005-05-27 | 2006-11-30 | Curalogic, A/S | Non-injection immunotherapy |
US8017152B2 (en) | 2005-05-27 | 2011-09-13 | Stratosphere Pharma Ab | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
EP1726299A3 (en) | 2005-05-27 | 2007-04-18 | StratoSphere Pharma AB | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
WO2007025441A1 (en) * | 2005-08-29 | 2007-03-08 | Tuo Jin | Polysaccharide microparticles containing biological agents: there preparation and applications |
ES2462519T3 (es) * | 2005-10-25 | 2014-05-23 | Artificial Cell Technologies, Inc. | Composiciones inmunógenas y procedimientos de uso |
US7842312B2 (en) | 2005-12-29 | 2010-11-30 | Cordis Corporation | Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same |
KR100956415B1 (ko) * | 2008-06-13 | 2010-05-06 | 이진호 | 고분자 구형입자의 제조방법 |
CN102209530B (zh) * | 2008-10-10 | 2013-05-15 | 普罗贝尔特医药公司 | 用于水产养殖的可口服给药的免疫刺激产品 |
JP5361407B2 (ja) * | 2009-01-21 | 2013-12-04 | 株式会社東芝 | X線画像診断装置、画像処理装置及び制御プログラム |
WO2012054807A2 (en) * | 2010-10-22 | 2012-04-26 | President And Fellows Of Harvard College | Vaccines comprising bisphosphonate and methods of use thereof |
BR112013014574B1 (pt) * | 2010-12-15 | 2019-10-15 | Speximo Ab | Emulsão ou espuma estabilizada por partícula, uso de uma emulsão estabilizada por partícula e formulação |
BR112014026957A8 (pt) * | 2012-05-03 | 2018-01-16 | Janssen R&D Ireland | micropartícula, composição compreendendo a mesma, seu uso e sistema de distribuição nasal relacionados ao tratamento de infecções do trato respiratório superior |
US11470811B2 (en) * | 2012-09-11 | 2022-10-18 | Pioneer Pet Products, Llc | Extruded granular absorbent |
SG11201507751YA (en) | 2013-03-21 | 2015-10-29 | Eupraxia Pharmaceuticals USA LLC | Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith |
EP2898894A1 (en) | 2014-01-27 | 2015-07-29 | LTS LOHMANN Therapie-Systeme AG | Nano-in-micro particles for intradermal delivery |
EP3310383B1 (en) * | 2015-06-19 | 2020-02-19 | Sillajen, Inc. | Compositions and methods for viral embolization |
AU2016343952A1 (en) | 2015-10-27 | 2018-05-10 | Eupraxia Pharmaceuticals Inc. | Sustained release formulations of local anesthetics |
CN106902716B (zh) * | 2017-02-27 | 2020-02-14 | 广西科学院 | 一种小粒径淀粉微球的制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4713249A (en) * | 1981-11-12 | 1987-12-15 | Schroeder Ulf | Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof |
JPH0699529B2 (ja) * | 1985-06-28 | 1994-12-07 | モンサント化成株式会社 | シアン化ビニル化合物/芳香族ビニル化合物共重合樹脂の製造方法 |
AU4109493A (en) * | 1992-04-20 | 1993-11-18 | Bruce K. Redding Jr. | Method and apparatus for the modification of starch and other polymers |
DE69505949T2 (de) * | 1994-02-17 | 1999-06-02 | Pankaj Hamilton Ontario Modi | Arzneimittel, impfstoffe und hormone in polylaktidbeschichteten mikropartikel |
US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
US5959102A (en) * | 1997-06-30 | 1999-09-28 | Rutgers University | Starch purification by thermally tolerant broad pH range proteolytic enzymes |
NL1006444C2 (nl) * | 1997-07-01 | 1999-01-05 | Inst Voor Agrotech Onderzoek | Inkapseling van werkzame stoffen. |
SE512663C2 (sv) * | 1997-10-23 | 2000-04-17 | Biogram Ab | Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer |
-
2001
- 2001-10-05 HU HU0302622A patent/HUP0302622A3/hu unknown
- 2001-10-05 CA CA002424892A patent/CA2424892A1/en not_active Abandoned
- 2001-10-05 AU AU2001294458A patent/AU2001294458B2/en not_active Ceased
- 2001-10-05 JP JP2002531996A patent/JP2004510723A/ja active Pending
- 2001-10-05 CA CA002424936A patent/CA2424936A1/en not_active Abandoned
- 2001-10-05 WO PCT/SE2001/002169 patent/WO2002028371A1/en not_active Application Discontinuation
- 2001-10-05 KR KR10-2003-7004508A patent/KR20030051687A/ko not_active Application Discontinuation
- 2001-10-05 CN CNB018168558A patent/CN100352427C/zh not_active Expired - Fee Related
- 2001-10-05 AU AU2001292529A patent/AU2001292529A1/en not_active Abandoned
- 2001-10-05 WO PCT/SE2001/002164 patent/WO2002028370A1/en active IP Right Grant
- 2001-10-05 AU AU9445801A patent/AU9445801A/xx active Pending
- 2001-10-05 EP EP01972895A patent/EP1322290A1/en not_active Withdrawn
- 2001-10-05 JP JP2002531997A patent/JP2004510724A/ja active Pending
- 2001-10-05 EP EP01975099A patent/EP1322291A1/en not_active Withdrawn
-
2002
- 2002-01-10 US US09/970,794 patent/US20020098203A1/en not_active Abandoned
-
2004
- 2004-07-13 HK HK04105106A patent/HK1061981A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1468093A (zh) | 2004-01-14 |
HUP0302622A3 (en) | 2006-07-28 |
WO2002028370A1 (en) | 2002-04-11 |
HK1061981A1 (en) | 2004-10-15 |
CA2424936A1 (en) | 2002-04-11 |
KR20030051687A (ko) | 2003-06-25 |
CN100352427C (zh) | 2007-12-05 |
US20020098203A1 (en) | 2002-07-25 |
AU9445801A (en) | 2002-04-15 |
CA2424892A1 (en) | 2002-04-11 |
JP2004510724A (ja) | 2004-04-08 |
EP1322291A1 (en) | 2003-07-02 |
AU2001292529A1 (en) | 2002-04-15 |
EP1322290A1 (en) | 2003-07-02 |
JP2004510723A (ja) | 2004-04-08 |
WO2002028371A1 (en) | 2002-04-11 |
AU2001294458B2 (en) | 2004-03-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0302622A2 (hu) | Ellenőrzött hatóanyag-leadású, biológiailag lebontható mikrorészecskék, amelyek csökkentett molekulatömegű, tisztított amilopektinalapú keményítőt tartalmaznak | |
SE0003615L (sv) | Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav | |
KR910015288A (ko) | 서방성 마이크로캡슐 | |
MXPA05003591A (es) | Materiales basados en ciclodextrina, composiciones y usos relacionados a los mismos. | |
BR0013720A (pt) | Formulação em pelota de liberação controlada | |
CY1117889T1 (el) | Πολυμερες γαλακτικου οξεος και διεργασια για την παραγωγη αυτου | |
BR9814729A (pt) | Método e composição de uma preparação oral de itraconazol | |
PL358103A1 (en) | Hydrophilic molecular disperse solutions of carvedilol | |
WO1998009597A3 (en) | Cushioning beads and tablet comprising the same capable of forming a suspension | |
BR0008059A (pt) | Composições de valdecoxib | |
ATE544447T1 (de) | Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung | |
DE69837945D1 (de) | Tablette, umfassend ein phosphatbindendes Polymer | |
KR940021071A (ko) | 생체기능조정물질 | |
PT85105B (pt) | Processo para a preparacao de composicoes farmaceuticas com libertacao controlada da substancia activa | |
HUP0000141A2 (hu) | Eljárás legfeljebb 90 tömeg% gyógyhatású anyagot tartalmazó pelletek előállítására | |
MY139606A (en) | Sustained-release composition and process for producing the same | |
Wu et al. | Time lasting S-nitrosoglutathione polymeric nanoparticles delay cellular protein S-nitrosation | |
ATE149826T1 (de) | Verfahren zur herstellung von festen pharmazeutischen retardformen | |
EP1061904A1 (de) | Nanopartikel, verfahren zu ihrer herstellung und ihre verwendung | |
BR0114512A (pt) | Suspensão coloidal, sólido pulverulento, processos de preparação, produtos intermediários de processo, especialidade farmacêutica, nutricional, fitossanitária ou cosmética e uso de uma suspensão coloidal estável | |
CA2326048A1 (en) | Peroral active agent suspension | |
BRPI0614080A2 (pt) | Composição e método para a preparação de uma cefalosporina nanoparticulada, para o tratamento de doença bacteriana e para a prevenção e/ou tratamento de osteoporose | |
JO2325B1 (en) | A pharmaceutical composition with a flavoring taste and a process to prepare it | |
Ma et al. | PCL/poloxamer 188 blend microsphere for paclitaxel delivery: Influence of poloxamer 188 on morphology and drug release | |
TR200703565T1 (tr) | Peroral uygulanabilir antimikrobiyal kompozisyon. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |