HUP0301920A2 - P anyag receptor antagonista és magnézium vegyület kombinációját tartalmazó agy-, gerinc- és idegsérülés kezelésére szolgáló injekciós készítmény - Google Patents

P anyag receptor antagonista és magnézium vegyület kombinációját tartalmazó agy-, gerinc- és idegsérülés kezelésére szolgáló injekciós készítmény

Info

Publication number
HUP0301920A2
HUP0301920A2 HU0301920A HUP0301920A HUP0301920A2 HU P0301920 A2 HUP0301920 A2 HU P0301920A2 HU 0301920 A HU0301920 A HU 0301920A HU P0301920 A HUP0301920 A HU P0301920A HU P0301920 A2 HUP0301920 A2 HU P0301920A2
Authority
HU
Hungary
Prior art keywords
magnesium compound
receptor antagonist
spinal
composition containing
nerve injury
Prior art date
Application number
HU0301920A
Other languages
English (en)
Inventor
Alan John Nimmo
Robert Vink
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Publication of HUP0301920A2 publication Critical patent/HUP0301920A2/hu
Publication of HUP0301920A3 publication Critical patent/HUP0301920A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány agy-, gerincvelő- és idegsérülések valamely P anyagreceptorral történő kezelésére vonatkozik, adott esetben valamelymagnéziumvegyülettel kombinálva. A találmány továbbá valamely P anyagreceptor antagonistát és valamely magnéziumvegyületet tartalmazókészítménynek a fenti kezelési eljárásban történő felhasználásáravonatkozik. Ó
HU0301920A 2000-01-18 2001-01-18 Injection composition containing p receptor antagonist and magnesium compound suitable for treating brain, spinal and nerve injury HUP0301920A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPQ5146A AUPQ514600A0 (en) 2000-01-18 2000-01-18 Brain injury treatment
PCT/AU2001/000046 WO2001052844A1 (en) 2000-01-18 2001-01-18 Brain, spinal and nerve injury treatment

Publications (2)

Publication Number Publication Date
HUP0301920A2 true HUP0301920A2 (hu) 2003-09-29
HUP0301920A3 HUP0301920A3 (en) 2010-03-29

Family

ID=3819274

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301920A HUP0301920A3 (en) 2000-01-18 2001-01-18 Injection composition containing p receptor antagonist and magnesium compound suitable for treating brain, spinal and nerve injury

Country Status (21)

Country Link
US (5) US6841551B2 (hu)
EP (1) EP1261335B1 (hu)
JP (1) JP4794794B2 (hu)
KR (1) KR100780119B1 (hu)
CN (1) CN1261095C (hu)
AU (2) AUPQ514600A0 (hu)
BR (1) BR0107695A (hu)
CA (1) CA2397723C (hu)
CZ (1) CZ20022804A3 (hu)
DE (1) DE60139244D1 (hu)
HK (1) HK1054872A1 (hu)
HR (1) HRP20020593B1 (hu)
HU (1) HUP0301920A3 (hu)
IL (2) IL150548A0 (hu)
MX (1) MXPA02007004A (hu)
NO (1) NO329320B1 (hu)
NZ (2) NZ534278A (hu)
RU (1) RU2276996C2 (hu)
WO (1) WO2001052844A1 (hu)
YU (1) YU54702A (hu)
ZA (1) ZA200205715B (hu)

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Also Published As

Publication number Publication date
RU2002121640A (ru) 2004-03-27
NZ534278A (en) 2005-08-26
NO329320B1 (no) 2010-09-27
HK1054872A1 (en) 2003-12-19
IL150548A0 (en) 2003-02-12
RU2276996C2 (ru) 2006-05-27
EP1261335A1 (en) 2002-12-04
CA2397723A1 (en) 2001-07-26
US6841551B2 (en) 2005-01-11
HUP0301920A3 (en) 2010-03-29
NO20023423D0 (no) 2002-07-17
US20180071333A1 (en) 2018-03-15
EP1261335B1 (en) 2009-07-15
BR0107695A (pt) 2002-10-15
CA2397723C (en) 2010-08-31
IL150548A (en) 2011-05-31
US20090253698A1 (en) 2009-10-08
CN1426302A (zh) 2003-06-25
KR100780119B1 (ko) 2007-11-27
US10201568B2 (en) 2019-02-12
DE60139244D1 (de) 2009-08-27
JP2003520232A (ja) 2003-07-02
US20050107380A1 (en) 2005-05-19
JP4794794B2 (ja) 2011-10-19
US20160030474A1 (en) 2016-02-04
CN1261095C (zh) 2006-06-28
EP1261335A4 (en) 2004-09-22
HRP20020593B1 (en) 2011-03-31
AUPQ514600A0 (en) 2000-02-10
US9186404B2 (en) 2015-11-17
NZ519990A (en) 2004-10-29
NO20023423L (no) 2002-09-16
KR20020075784A (ko) 2002-10-05
WO2001052844A1 (en) 2001-07-26
ZA200205715B (en) 2003-10-17
PL358251A1 (en) 2004-08-09
AU782799B2 (en) 2005-09-01
MXPA02007004A (es) 2004-10-15
US20030109417A1 (en) 2003-06-12
CZ20022804A3 (cs) 2002-11-13
HRP20020593A2 (en) 2005-10-31
YU54702A (sh) 2006-01-16
AU2656001A (en) 2001-07-31

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