HUP0300875A3 - Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine - Google Patents

Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine

Info

Publication number: HUP0300875A3
Authority: HU; Hungary
Prior art keywords: olanzapine; hydrates; conversion; preparation; crystalline forms
Prior art date: 2000-08-31

Application number

HU0300875A

Other languages

Hungarian (hu)

Original Assignee

Reddy S Lab Ltd Hyderabad Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-31

Filing date

2001-03-07

Publication date

2005-09-28

2001-03-07 Application filed by Reddy S Lab Ltd Hyderabad Dr filed Critical Reddy S Lab Ltd Hyderabad Dr

2003-12-29 Publication of HUP0300875A2 publication Critical patent/HUP0300875A2/en

2005-09-28 Publication of HUP0300875A3 publication Critical patent/HUP0300875A3/en

Links

KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title 2
229960005017 olanzapine Drugs 0.000 title 2
238000006243 chemical reaction Methods 0.000 title 1
150000004677 hydrates Chemical class 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics

HU0300875A 2000-08-31 2001-03-07 Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine HUP0300875A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IN709CH2000		2000-08-31
IN711CH2000		2000-08-31
PCT/US2001/007258 WO2002018390A1 (en)	2000-08-31	2001-03-07	Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine

Publications (2)

Publication Number	Publication Date
HUP0300875A2 HUP0300875A2 (en)	2003-12-29
HUP0300875A3 true HUP0300875A3 (en)	2005-09-28

Family

ID=26324874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0300875A HUP0300875A3 (en)	2000-08-31	2001-03-07	Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine

Country Status (12)

Country	Link
EP (1)	EP1313742A1 (en)
JP (1)	JP2004507548A (en)
AU (1)	AU2001243475A1 (en)
BR (1)	BR0114031A (en)
CA (1)	CA2420987A1 (en)
CZ (1)	CZ2003566A3 (en)
HU (1)	HUP0300875A3 (en)
IL (1)	IL154688A0 (en)
NO (1)	NO20030926L (en)
RU (1)	RU2003108745A (en)
SK (1)	SK2502003A3 (en)
WO (1)	WO2002018390A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003037903A1 (en) *	2001-10-29	2003-05-08	Dr. Reddy's Laboratories Ltd.	Olanzapine dihydrate-ii a process for its preparation and use thereof
WO2003091260A1 (en) *	2002-04-23	2003-11-06	Dr. Reddy's Laboratories Limited	Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
AU2002251329A1 (en) *	2002-04-25	2003-11-10	Generics (Uk) Limited	Novel crystalline forms of celecoxib and other compounds
PL196814B1 (en)	2002-05-17	2008-02-29	Inst Farmaceutyczny	Method of obtaining polymorphous form of i olansapine
WO2003101997A1 (en)	2002-05-31	2003-12-11	Geneva Pharmaceuticals, Inc.	Process of preparation of olanzapine form i
SI21270A (en)	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Crystal forms of olanzapine and procedures for their preparation
PL202856B1 (en) *	2002-12-20	2009-07-31	Adamed Spo & Lstrok Ka Z Ogran	Method of obtaining pharmaceutically pure polymorphic form of I olanzapine
AU2003300324A1 (en)	2002-12-24	2004-07-22	Teva Pharmaceutical Industries Ltd.	Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
ES2308304T3 (en)	2003-12-22	2008-12-01	Teva Pharmaceutical Industries Ltd.	OLANZAPINE PREPARATION PROCEDURES.
AR047460A1 (en) *	2004-01-27	2006-01-18	Synthon Bv	PROCESS FOR THE MANUFACTURE OF 2-METHYL-4- (4-METHYL-1-PIPERAZINYL) ACETATE -10H-TIENO [2,3-B] [1,5] BENZODIAZEPIN (OLANZAPINE ACETATE)
ATE504588T1 (en)	2004-01-27	2011-04-15	Synthon Bv	STABLE SALTS OF OLANZAPINE
WO2005080401A1 (en) *	2004-02-19	2005-09-01	Neuland Laboratories Limited	Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2005107375A2 (en) *	2004-05-06	2005-11-17	Matrix Laboratories Ltd	Process for the preparation of olanzapine form-i
US8044196B2 (en)	2004-07-14	2011-10-25	Jubilant Organosys Limited	Process for producing pure form of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
EP1781666A1 (en) *	2004-07-14	2007-05-09	Shasun Chemicals and Drugs Limited	Improved process for making form i of olanzapine.
ES2253091B1 (en)	2004-07-27	2007-02-01	Inke, S.A.	MIXED SOLVATO OF OLANZAPINE, PROCEDURE FOR OBTAINING AND PROCEDURE OF OBTAINING THE FORM I OF OLANZAPINE FROM THE SAME.
WO2006025065A1 (en) *	2004-08-31	2006-03-09	Lee Pharma Private Limited	A process for the preparation of anhydrous olanzopine hydrochloride of form-1
WO2006027800A1 (en)	2004-09-06	2006-03-16	Shasun Chemicals And Drugs Limited	A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
EP1838716B1 (en) *	2005-01-05	2011-06-01	Eli Lilly And Company	Olanzapine pamoate dihydrate
WO2006102176A2 (en) *	2005-03-21	2006-09-28	Dr. Reddy's Laboratories Ltd.	Process for preparing crystalline form i of olanzapine
HUP0501046A2 (en) *	2005-11-11	2007-08-28	Egis Gyogyszergyar Nyilvanosan	Process for the preparation of olanzapine
US7834176B2 (en)	2006-01-26	2010-11-16	Sandoz Ag	Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
PL381564A1 (en)	2007-01-22	2008-08-04	Koźluk Tomasz Nobilus Ent	The manner of production of basically clean variety of polymorphic olanzapine
AU2008249766A1 (en) *	2007-05-15	2008-11-20	Generics [Uk] Limited	Process for the purification of olanzapine
EP2292624A1 (en)	2009-07-20	2011-03-09	LEK Pharmaceuticals d.d.	Process for the purification of olanzapine
CN102093386B (en) *	2011-01-05	2016-06-01	浙江华海药业股份有限公司	A kind of method preparing Zyprexa crystal form II
JP6008734B2 (en) *	2012-12-20	2016-10-19	株式会社トクヤマ	Olanzapine type II crystal production method
DK3466934T3 (en)	2016-05-31	2024-04-15	Taiho Pharmaceutical Co Ltd	SULFONAMIDE COMPOUNDS OR SALT THEREOF AS RIBONUCLEOTIDE REDUCTASE INHIBITORS FOR THE TREATMENT OF CANCER

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9009229D0 (en)	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
EG23659A (en) *	1995-03-24	2007-03-26	Lilly Co Eli	Process and crystal forms of methyl-thieno-benzodiazepine
ZA978515B (en) *	1996-09-23	1999-03-23	Lilly Co Eli	Intermediates and process for preparing olanzapine
EA001881B1 (en) *	1996-09-23	2001-10-22	Эли Лилли Энд Компани	Olanzapine dehydrate d

2001
- 2001-03-07 SK SK250-2003A patent/SK2502003A3/en unknown
- 2001-03-07 WO PCT/US2001/007258 patent/WO2002018390A1/en not_active Application Discontinuation
- 2001-03-07 HU HU0300875A patent/HUP0300875A3/en unknown
- 2001-03-07 CZ CZ2003566A patent/CZ2003566A3/en unknown
- 2001-03-07 BR BR0114031-0A patent/BR0114031A/en not_active IP Right Cessation
- 2001-03-07 CA CA002420987A patent/CA2420987A1/en not_active Abandoned
- 2001-03-07 AU AU2001243475A patent/AU2001243475A1/en not_active Abandoned
- 2001-03-07 EP EP01916449A patent/EP1313742A1/en not_active Withdrawn
- 2001-03-07 JP JP2002523905A patent/JP2004507548A/en active Pending
- 2001-03-07 RU RU2003108745/04A patent/RU2003108745A/en not_active Application Discontinuation
- 2001-03-07 IL IL15468801A patent/IL154688A0/en unknown
2003
- 2003-02-27 NO NO20030926A patent/NO20030926L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL154688A0 (en)	2003-09-17
RU2003108745A (en)	2005-01-10
AU2001243475A1 (en)	2002-03-13
WO2002018390A1 (en)	2002-03-07
NO20030926D0 (en)	2003-02-27
SK2502003A3 (en)	2004-03-02
NO20030926L (en)	2003-04-24
CA2420987A1 (en)	2002-03-07
HUP0300875A2 (en)	2003-12-29
BR0114031A (en)	2003-09-09
CZ2003566A3 (en)	2004-01-14
JP2004507548A (en)	2004-03-11
EP1313742A1 (en)	2003-05-28

Publication	Publication Date	Title
HUP0300875A3 (en)	2005-09-28	Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
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PL361052A1 (en)	2004-09-20	Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
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AU2003243153A8 (en)	2003-11-10	Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
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