HUP0104655A2 - Szív-érrendszeri hatóanyagok kombinációi - Google Patents

Szív-érrendszeri hatóanyagok kombinációi

Info

Publication number
HUP0104655A2
HUP0104655A2 HU0104655A HUP0104655A HUP0104655A2 HU P0104655 A2 HUP0104655 A2 HU P0104655A2 HU 0104655 A HU0104655 A HU 0104655A HU P0104655 A HUP0104655 A HU P0104655A HU P0104655 A2 HUP0104655 A2 HU P0104655A2
Authority
HU
Hungary
Prior art keywords
inhibitor
combinations
acid derivative
microsomal
cetp
Prior art date
Application number
HU0104655A
Other languages
English (en)
Inventor
Bradley T. Keller
Rodney W. Lappe
David B. Reitz
Joseph R. Schuh
James A. Sikorski
Samuel J. Tremont
Original Assignee
G.D. Searle Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22352512&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0104655(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by G.D. Searle Llc filed Critical G.D. Searle Llc
Publication of HUP0104655A2 publication Critical patent/HUP0104655A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A tal lm ny szív-érrendszeri ter pi s vegyület kombin cióit ismertetiszív-érrendszeri betegség, ezen belül hiperkoleszterinémia ésérszűkület megelőzésére vagy kezelésére. Az ismertetett kombin ciókcsípőbél-epesav transzport inhibitort egy koleszteril észtertranszport protein (CETP) inhibitorral, fibrinsavsz rmazékkal,nikotinsavsz rmazékkal, mikroszóm s triglicerid transzfer protein-inhibitorral, koleszterinfelszívód s-antagonist val, fitoszterinnel,sztanollal, magas vérnyom s elleni szerrel vagy m s szerekkel kombinlva tartalmaznak. Tov bbi kombin ciók k"zé tartozik a CETP-inhibitorfibrinsav-sz rmazékkal, nikotinsav-sz rmazékkal, epesav-elvonószerrel, mikroszóm s triglicerid transzfer protein-inhibitorral,koleszterinfelszívód s-antagonist val vagy m s vegyületekkel képzettkombin ciói. Ó
HU0104655A 1998-12-23 1999-12-17 Szív-érrendszeri hatóanyagok kombinációi HUP0104655A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11395598P 1998-12-23 1998-12-23
PCT/US1999/027946 WO2000038725A1 (en) 1998-12-23 1999-12-17 Combinations for cardiovascular indications

Publications (1)

Publication Number Publication Date
HUP0104655A2 true HUP0104655A2 (hu) 2002-04-29

Family

ID=22352512

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104655A HUP0104655A2 (hu) 1998-12-23 1999-12-17 Szív-érrendszeri hatóanyagok kombinációi

Country Status (23)

Country Link
US (1) US20040058908A1 (hu)
EP (2) EP1140187B1 (hu)
JP (1) JP2002533411A (hu)
KR (1) KR20020002367A (hu)
CN (1) CN1342091A (hu)
AR (1) AR037482A1 (hu)
AT (1) ATE248606T1 (hu)
AU (1) AU779264B2 (hu)
BR (1) BR9916564A (hu)
CA (1) CA2356515A1 (hu)
CZ (1) CZ20012344A3 (hu)
DE (1) DE69911058T2 (hu)
DK (1) DK1140187T3 (hu)
EA (1) EA200100704A1 (hu)
ES (1) ES2207330T3 (hu)
HU (1) HUP0104655A2 (hu)
IL (1) IL143944A0 (hu)
MX (1) MXPA01006468A (hu)
NO (1) NO20013157L (hu)
NZ (1) NZ512532A (hu)
PT (1) PT1140187E (hu)
WO (1) WO2000038725A1 (hu)
ZA (5) ZA200105062B (hu)

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CZ20012344A3 (cs) 2002-01-16
EA200100704A1 (ru) 2002-02-28
ES2207330T3 (es) 2004-05-16
AR037482A1 (es) 2004-11-17
ZA200105056B (en) 2002-06-20
EP1140187B1 (en) 2003-09-03
DK1140187T3 (da) 2003-12-22
AU2157700A (en) 2000-07-31
US20040058908A1 (en) 2004-03-25
KR20020002367A (ko) 2002-01-09
ZA200105059B (en) 2002-06-20
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DE69911058T2 (de) 2004-06-03
DE69911058D1 (de) 2003-10-09
NO20013157L (no) 2001-08-22
ZA200105060B (en) 2002-09-20
BR9916564A (pt) 2002-01-29
EP1354604A1 (en) 2003-10-22
WO2000038725A1 (en) 2000-07-06
EP1140187A1 (en) 2001-10-10
CN1342091A (zh) 2002-03-27
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ATE248606T1 (de) 2003-09-15
IL143944A0 (en) 2002-04-21

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