HUP0104388A2 - Béta-agonistákból és további antidiabetikus szerekből álló kombinációk - Google Patents
Béta-agonistákból és további antidiabetikus szerekből álló kombinációkInfo
- Publication number
- HUP0104388A2 HUP0104388A2 HU0104388A HUP0104388A HUP0104388A2 HU P0104388 A2 HUP0104388 A2 HU P0104388A2 HU 0104388 A HU0104388 A HU 0104388A HU P0104388 A HUP0104388 A HU P0104388A HU P0104388 A2 HUP0104388 A2 HU P0104388A2
- Authority
- HU
- Hungary
- Prior art keywords
- agonist
- antidiabetic agent
- diabetes mellitus
- betha
- combinations
- Prior art date
Links
- 239000003472 antidiabetic agent Substances 0.000 title abstract 3
- 229940125708 antidiabetic agent Drugs 0.000 title abstract 3
- 239000000556 agonist Substances 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 229940077274 Alpha glucosidase inhibitor Drugs 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 229940122199 Insulin secretagogue Drugs 0.000 abstract 1
- 229940122355 Insulin sensitizer Drugs 0.000 abstract 1
- 239000003888 alpha glucosidase inhibitor Substances 0.000 abstract 1
- 229940125388 beta agonist Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Abstract
A találmány tárgya eljárás diabetes mellitus, különösen 2. típusúdiabetes mellitus és diabetes mellitusszal kapcsolatos állapotokkezelésére emlősökben, például emberekben, amelynek során egy ilyenkezelést igénylő emlősnek beadják egy béta-3-agonista és egy másikantidiabetikus szer, például egy alfa-glükozidáz-inhibitor, egybiguanidin, egy inzulin secretagogum, egy inzulinszenzibilizátor vagyinzulin hatásos, nem toxikus és gyógyászatilag elfogadhatómennyiségét. A találmány tárgyát képezi egy olyan gyógyszerkészítményis, amely egy béta-agonistát és egy másik antidiabetikus szert,valamint gyógyászatilag elfogadható hordozót tartalmaz. Ó
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9824791.9A GB9824791D0 (en) | 1998-11-11 | 1998-11-11 | Novel methods of treatment |
| GBGB9824789.3A GB9824789D0 (en) | 1998-11-11 | 1998-11-11 | Novel method of treatment |
| GBGB9824790.1A GB9824790D0 (en) | 1998-11-11 | 1998-11-11 | Novel method of treatment |
| PCT/GB1999/003755 WO2000027434A1 (en) | 1998-11-11 | 1999-11-11 | Combinations comprising a beta-agonist and a further antidiabetic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0104388A2 true HUP0104388A2 (hu) | 2002-03-28 |
| HUP0104388A3 HUP0104388A3 (en) | 2002-12-28 |
Family
ID=27269550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0104388A HUP0104388A3 (en) | 1998-11-11 | 1999-11-11 | Combinations comprising a betha-agonist and a further antidiabetic agent |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1128845A1 (hu) |
| JP (1) | JP2002529430A (hu) |
| KR (1) | KR20010075698A (hu) |
| CN (1) | CN1332638A (hu) |
| AU (1) | AU766928B2 (hu) |
| BR (1) | BR9915214A (hu) |
| CA (1) | CA2350062A1 (hu) |
| CZ (1) | CZ20011655A3 (hu) |
| HK (1) | HK1041201A1 (hu) |
| HU (1) | HUP0104388A3 (hu) |
| IL (1) | IL143004A0 (hu) |
| NO (1) | NO20012300L (hu) |
| PL (1) | PL348154A1 (hu) |
| TR (1) | TR200101336T2 (hu) |
| WO (1) | WO2000027434A1 (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0016631A (pt) * | 1999-12-23 | 2003-01-07 | Novartis Ag | Uso de agentes hipoglicêmico para tratar metabolismo de glicose depreciada |
| AU2007201729B2 (en) * | 1999-12-23 | 2010-02-25 | Novartis Ag | Use of hypoglycemic agent for treating impaired glucose metabolism |
| AU2382601A (en) * | 1999-12-24 | 2001-07-09 | Smithkline Beecham Plc | Novel method of treatment |
| EP1258253A1 (en) * | 2000-01-28 | 2002-11-20 | Asahi Kasei Kabushiki Kaisha | Novel remedies with the use of beta3 agonist |
| AU2001252573A1 (en) * | 2000-04-28 | 2001-11-12 | Asahi Kasei Kabushiki Kaisha | Novel substituted tricyclic compounds |
| WO2001083452A1 (fr) * | 2000-04-28 | 2001-11-08 | Asahi Kasei Kabushiki Kaisha | Nouveaux composes tricycliques |
| WO2006132196A1 (ja) * | 2005-06-08 | 2006-12-14 | Asahi Kasei Pharma Corporation | β３作動薬を含有する新規な医薬 |
| US11053255B2 (en) | 2015-06-22 | 2021-07-06 | Georgetown University | Synthesis of mahanine and related compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2071629C (en) * | 1990-02-09 | 1997-12-30 | Jerry R. Colca | Use of insulin sensitizing agents to treat hypertension |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| WO1997025311A1 (fr) * | 1996-01-10 | 1997-07-17 | Asahi Kasei Kogyo Kabushiki Kaisha | Nouveaux composes tricycliques et compositions medicamenteuses contenant ces composes |
-
1999
- 1999-11-11 IL IL14300499A patent/IL143004A0/xx unknown
- 1999-11-11 KR KR1020017005958A patent/KR20010075698A/ko not_active Application Discontinuation
- 1999-11-11 EP EP99954217A patent/EP1128845A1/en not_active Withdrawn
- 1999-11-11 WO PCT/GB1999/003755 patent/WO2000027434A1/en not_active Application Discontinuation
- 1999-11-11 BR BR9915214-2A patent/BR9915214A/pt not_active Application Discontinuation
- 1999-11-11 CZ CZ20011655A patent/CZ20011655A3/cs unknown
- 1999-11-11 JP JP2000580663A patent/JP2002529430A/ja not_active Withdrawn
- 1999-11-11 TR TR2001/01336T patent/TR200101336T2/xx unknown
- 1999-11-11 AU AU10634/00A patent/AU766928B2/en not_active Ceased
- 1999-11-11 PL PL99348154A patent/PL348154A1/xx not_active Application Discontinuation
- 1999-11-11 HU HU0104388A patent/HUP0104388A3/hu unknown
- 1999-11-11 CN CN99815382A patent/CN1332638A/zh active Pending
- 1999-11-11 CA CA002350062A patent/CA2350062A1/en not_active Abandoned
-
2001
- 2001-05-10 NO NO20012300A patent/NO20012300L/no not_active Application Discontinuation
-
2002
- 2002-02-08 HK HK02101022.8A patent/HK1041201A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL143004A0 (en) | 2002-04-21 |
| PL348154A1 (en) | 2002-05-06 |
| HK1041201A1 (zh) | 2002-07-05 |
| JP2002529430A (ja) | 2002-09-10 |
| NO20012300L (no) | 2001-07-03 |
| CZ20011655A3 (cs) | 2002-06-12 |
| EP1128845A1 (en) | 2001-09-05 |
| WO2000027434A1 (en) | 2000-05-18 |
| AU1063400A (en) | 2000-05-29 |
| KR20010075698A (ko) | 2001-08-09 |
| BR9915214A (pt) | 2001-12-18 |
| NO20012300D0 (no) | 2001-05-10 |
| TR200101336T2 (tr) | 2001-11-21 |
| CN1332638A (zh) | 2002-01-23 |
| AU766928B2 (en) | 2003-10-23 |
| HUP0104388A3 (en) | 2002-12-28 |
| CA2350062A1 (en) | 2000-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |