HUP0100580A2 - Oldott paroxetint tartalmazó készítmények - Google Patents
Oldott paroxetint tartalmazó készítményekInfo
- Publication number
- HUP0100580A2 HUP0100580A2 HU0100580A HUP0100580A HUP0100580A2 HU P0100580 A2 HUP0100580 A2 HU P0100580A2 HU 0100580 A HU0100580 A HU 0100580A HU P0100580 A HUP0100580 A HU P0100580A HU P0100580 A2 HUP0100580 A2 HU P0100580A2
- Authority
- HU
- Hungary
- Prior art keywords
- paroxetine
- solid
- hemihydrate
- subject matter
- solutions
- Prior art date
Links
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title abstract 5
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 5
- 229960002296 paroxetine Drugs 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000012051 hydrophobic carrier Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 239000008188 pellet Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
- 239000006104 solid solution Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A tal lm ny olyan, paroxetint tartalmazó gyógyszerkészítményekrevonatkozik, amelyekben a paroxetin egy szil rd, félszil rd vagyfolyékony hordozóval alkotott oldat form j ban van jelen. Az oldatokkapszul kba t"lthetők, illetve az "nhordozó szil rd oldatok szil rddózisform kk , péld ul tablett kk vagy pelletekké alakíthatók. A tal lm ny t rgy t képezik az olyan, új, folyékony készítményekis, amelyekben a paroxetin olajokban és/vagy lipidekben t"rténő oldóds hoz szolubiliz ló szereket alkalmaznak. A tal lm ny t rgy t képeziktov bb olyan elj r sok is, amelyekben a paroxetin hemihidr ttól eltérőm s form inak a hemihidr tt t"rténő talakul s t megakad lyozandó,vízmentes vagy hidrofób hordozókat vagy vivőanyagokat alkalmaznak. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9724544.3A GB9724544D0 (en) | 1997-11-21 | 1997-11-21 | Novel Formulation |
PCT/GB1998/003471 WO1999026625A1 (en) | 1997-11-21 | 1998-11-18 | Formulations comprising dissolved paroxetine |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0100580A2 true HUP0100580A2 (hu) | 2002-04-29 |
HUP0100580A3 HUP0100580A3 (en) | 2002-05-28 |
Family
ID=10822374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0100580A HUP0100580A3 (en) | 1997-11-21 | 1998-11-18 | Formulations comprising dissolved paroxetine |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1033986A1 (hu) |
JP (1) | JP2001523718A (hu) |
KR (1) | KR20010032320A (hu) |
CN (1) | CN1279608A (hu) |
AP (1) | AP2000001821A0 (hu) |
AR (1) | AR015485A1 (hu) |
AU (1) | AU1168099A (hu) |
BG (1) | BG104527A (hu) |
BR (1) | BR9814220A (hu) |
CO (1) | CO4970832A1 (hu) |
DZ (1) | DZ2658A1 (hu) |
EA (1) | EA200000552A1 (hu) |
GB (1) | GB9724544D0 (hu) |
HU (1) | HUP0100580A3 (hu) |
IL (1) | IL136106A0 (hu) |
MA (1) | MA24704A1 (hu) |
NO (1) | NO20002590L (hu) |
OA (1) | OA11385A (hu) |
PE (1) | PE20000381A1 (hu) |
PL (1) | PL340555A1 (hu) |
SK (1) | SK7342000A3 (hu) |
TR (1) | TR200001423T2 (hu) |
WO (1) | WO1999026625A1 (hu) |
ZA (1) | ZA9810637B (hu) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9810180D0 (en) * | 1998-05-13 | 1998-07-08 | Smithkline Beecham Plc | Novel formulation |
JP4854115B2 (ja) * | 1999-03-12 | 2012-01-18 | エイシカ ファーマシューティカルス リミテッド | 無水パロキセチン用安定製剤形 |
ES2206254T3 (es) | 1999-07-01 | 2004-05-16 | Italfarmaco S.P.A. | Complejos de paroxetina con ciclodextrinas o derivados de ciclodextrinas. |
DE19930454A1 (de) * | 1999-07-02 | 2001-01-04 | Knoll Ag | Feste Paroxetin enthaltende Zubereitungen |
US6720003B2 (en) | 2001-02-16 | 2004-04-13 | Andrx Corporation | Serotonin reuptake inhibitor formulations |
DE60222803T2 (de) * | 2001-12-21 | 2008-07-17 | Supernus Pharmaceuticals, Inc. | Orale kapselformulierung mit verbesserter physikalischer stabilität |
SE0200475D0 (sv) * | 2002-02-15 | 2002-02-15 | Ltp Lipid Technologies Provide | Oral farmaceutisk beredning |
WO2006119779A2 (en) * | 2005-05-10 | 2006-11-16 | Lifecycle Pharma A/S | A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution |
US20120322752A1 (en) * | 2009-12-08 | 2012-12-20 | Sung Kyun Lee | SOLID DISPERSIONS CONTAINING 20-O-beta-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL |
GB201020032D0 (en) * | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
CN103961333B (zh) * | 2014-05-07 | 2020-02-21 | 浙江华海药业股份有限公司 | 甲磺酸帕罗西汀胶囊及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3768536B2 (ja) * | 1995-04-03 | 2006-04-19 | アボツト・ラボラトリーズ | 低温溶融性薬物と制御放出のための添加物との均質混合物 |
EA002034B1 (ru) * | 1997-01-15 | 2001-12-24 | Смитклайн Бичам Плс | Композиция на основе пароксетина |
-
1997
- 1997-11-21 GB GBGB9724544.3A patent/GB9724544D0/en not_active Ceased
-
1998
- 1998-11-18 IL IL13610698A patent/IL136106A0/xx unknown
- 1998-11-18 AP APAP/P/2000/001821A patent/AP2000001821A0/en unknown
- 1998-11-18 AU AU11680/99A patent/AU1168099A/en not_active Abandoned
- 1998-11-18 CN CN98811404A patent/CN1279608A/zh active Pending
- 1998-11-18 BR BR9814220-8A patent/BR9814220A/pt not_active Application Discontinuation
- 1998-11-18 WO PCT/GB1998/003471 patent/WO1999026625A1/en not_active Application Discontinuation
- 1998-11-18 EA EA200000552A patent/EA200000552A1/ru unknown
- 1998-11-18 HU HU0100580A patent/HUP0100580A3/hu unknown
- 1998-11-18 DZ DZ980268A patent/DZ2658A1/xx active
- 1998-11-18 JP JP2000521827A patent/JP2001523718A/ja active Pending
- 1998-11-18 KR KR1020007005532A patent/KR20010032320A/ko not_active Application Discontinuation
- 1998-11-18 PL PL98340555A patent/PL340555A1/xx unknown
- 1998-11-18 TR TR2000/01423T patent/TR200001423T2/xx unknown
- 1998-11-18 EP EP98954631A patent/EP1033986A1/en not_active Withdrawn
- 1998-11-18 SK SK734-2000A patent/SK7342000A3/sk unknown
- 1998-11-18 PE PE1998001126A patent/PE20000381A1/es not_active Application Discontinuation
- 1998-11-19 MA MA25357A patent/MA24704A1/fr unknown
- 1998-11-19 AR ARP980105880A patent/AR015485A1/es unknown
- 1998-11-20 ZA ZA9810637A patent/ZA9810637B/xx unknown
- 1998-11-20 CO CO98068459A patent/CO4970832A1/es unknown
-
2000
- 2000-05-19 OA OA1200000153A patent/OA11385A/en unknown
- 2000-05-19 NO NO20002590A patent/NO20002590L/no not_active Application Discontinuation
- 2000-06-13 BG BG104527A patent/BG104527A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999026625A1 (en) | 1999-06-03 |
DZ2658A1 (fr) | 2003-03-22 |
AU1168099A (en) | 1999-06-15 |
OA11385A (en) | 2004-01-27 |
EA200000552A1 (ru) | 2000-10-30 |
CN1279608A (zh) | 2001-01-10 |
PE20000381A1 (es) | 2000-05-07 |
GB9724544D0 (en) | 1998-01-21 |
AR015485A1 (es) | 2001-05-02 |
CO4970832A1 (es) | 2000-11-07 |
NO20002590D0 (no) | 2000-05-19 |
NO20002590L (no) | 2000-07-19 |
KR20010032320A (ko) | 2001-04-16 |
HUP0100580A3 (en) | 2002-05-28 |
SK7342000A3 (en) | 2000-12-11 |
TR200001423T2 (tr) | 2000-10-23 |
BG104527A (en) | 2001-04-30 |
AP2000001821A0 (en) | 2000-06-30 |
EP1033986A1 (en) | 2000-09-13 |
JP2001523718A (ja) | 2001-11-27 |
ZA9810637B (en) | 2000-05-22 |
MA24704A1 (fr) | 1999-07-01 |
BR9814220A (pt) | 2001-12-26 |
IL136106A0 (en) | 2001-05-20 |
PL340555A1 (en) | 2001-02-12 |
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