HUP0004840A2 - Eljárás kolchikon vegyületeknek a megfelelő 3-glikozil származékokká történő biotranszformációjára - Google Patents
Eljárás kolchikon vegyületeknek a megfelelő 3-glikozil származékokká történő biotranszformációjáraInfo
- Publication number
- HUP0004840A2 HUP0004840A2 HU0004840A HUP0004840A HUP0004840A2 HU P0004840 A2 HUP0004840 A2 HU P0004840A2 HU 0004840 A HU0004840 A HU 0004840A HU P0004840 A HUP0004840 A HU P0004840A HU P0004840 A2 HUP0004840 A2 HU P0004840A2
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- biotransformation
- glycosyl derivatives
- colchicone
- colchicone compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000036983 biotransformation Effects 0.000 title abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány tárgyát kolchicinszerű vegyületeknek a megfelelő 3-O-glikozil-származékokká történő biotranszformációja képezi, amelyetkiválasztott mikrobiológiai törzsek segítségével hajtanak végre. Atalálmány szerinti eljárás - az említett kolchikonvegyületekbőlkiindulva - olyan vegyületeket eredményez magas kitermeléssel és nagytisztaságban, amelyek kizárólag az A aromás gyűrű C-3 pozíciójábanvannak glikozilálva. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97MI002255A IT1295272B1 (it) | 1997-10-03 | 1997-10-03 | Biotrasformazione di composti colchiconici nei corrispondenti 3- glicosilderivati |
PCT/EP1998/006226 WO1999018229A1 (en) | 1997-10-03 | 1998-09-30 | A process for the biotransformation of colchicone compounds into the corresponding 3-glycosyl derivatives |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0004840A2 true HUP0004840A2 (hu) | 2001-04-28 |
HUP0004840A3 HUP0004840A3 (en) | 2002-10-28 |
HU225686B1 HU225686B1 (en) | 2007-06-28 |
Family
ID=11377985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0004840A HU225686B1 (en) | 1997-10-03 | 1998-09-30 | A process for the biotransformation of colchicone compounds into the corresponding 3-glycosyl derivatives |
Country Status (21)
Country | Link |
---|---|
US (1) | US6372458B1 (hu) |
EP (1) | EP1019521B1 (hu) |
KR (1) | KR100536676B1 (hu) |
CN (1) | CN1188527C (hu) |
AT (1) | ATE328106T1 (hu) |
AU (1) | AU745222B2 (hu) |
CA (1) | CA2305046C (hu) |
CZ (1) | CZ295749B6 (hu) |
DE (1) | DE69834736T2 (hu) |
DK (1) | DK1019521T3 (hu) |
ES (1) | ES2264214T3 (hu) |
HK (1) | HK1031896A1 (hu) |
HU (1) | HU225686B1 (hu) |
IL (1) | IL134566A (hu) |
IT (1) | IT1295272B1 (hu) |
NO (1) | NO320096B1 (hu) |
PL (1) | PL190865B1 (hu) |
PT (1) | PT1019521E (hu) |
RU (1) | RU2218409C2 (hu) |
SK (1) | SK285923B6 (hu) |
WO (1) | WO1999018229A1 (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040175782A1 (en) * | 2003-03-06 | 2004-09-09 | Tethys Research Llc | Biotransformation of compounds using non-prokaryotic microalgae |
PT1745140E (pt) * | 2004-05-12 | 2009-09-30 | Indena Spa | Biotransformação de compostos colchicinóides |
KR20140014072A (ko) * | 2010-09-22 | 2014-02-05 | 엘리시안 라이프 사이언스이즈 프라이빗 리미티드 | 콜키시노이드 화합물의 미생물학적 생물전환 방법 |
WO2015097567A1 (en) | 2013-12-23 | 2015-07-02 | Alkaloids Corporation | Process for the conversion of colchicinoids to their 3-glycosylated derivatives via their respective 3-demethyl analogues |
CN105861601B (zh) * | 2016-04-29 | 2019-05-24 | 中国药科大学 | 一种生物转化制备二氢去氢双松柏醇葡萄糖单糖苷(hmzg)的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1344157A (fr) * | 1959-05-22 | 1963-11-29 | Roussel Uclaf | Nouvelles colchicines et leur procédé d'obtention |
JPS5233195B2 (hu) * | 1971-09-30 | 1977-08-26 | ||
IT1285777B1 (it) * | 1996-10-07 | 1998-06-18 | Indena Spa | Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati |
-
1997
- 1997-10-03 IT IT97MI002255A patent/IT1295272B1/it active IP Right Grant
-
1998
- 1998-09-30 WO PCT/EP1998/006226 patent/WO1999018229A1/en active IP Right Grant
- 1998-09-30 DK DK98952675T patent/DK1019521T3/da active
- 1998-09-30 HU HU0004840A patent/HU225686B1/hu not_active IP Right Cessation
- 1998-09-30 IL IL13456698A patent/IL134566A/en not_active IP Right Cessation
- 1998-09-30 DE DE69834736T patent/DE69834736T2/de not_active Expired - Lifetime
- 1998-09-30 EP EP98952675A patent/EP1019521B1/en not_active Expired - Lifetime
- 1998-09-30 KR KR10-2000-7003216A patent/KR100536676B1/ko not_active IP Right Cessation
- 1998-09-30 AT AT98952675T patent/ATE328106T1/de active
- 1998-09-30 PL PL339620A patent/PL190865B1/pl unknown
- 1998-09-30 CZ CZ20001196A patent/CZ295749B6/cs not_active IP Right Cessation
- 1998-09-30 PT PT98952675T patent/PT1019521E/pt unknown
- 1998-09-30 AU AU10283/99A patent/AU745222B2/en not_active Ceased
- 1998-09-30 RU RU2000111512/13A patent/RU2218409C2/ru not_active IP Right Cessation
- 1998-09-30 CA CA002305046A patent/CA2305046C/en not_active Expired - Fee Related
- 1998-09-30 CN CNB988098180A patent/CN1188527C/zh not_active Expired - Fee Related
- 1998-09-30 ES ES98952675T patent/ES2264214T3/es not_active Expired - Lifetime
- 1998-09-30 SK SK483-2000A patent/SK285923B6/sk not_active IP Right Cessation
-
2000
- 2000-03-31 US US09/539,867 patent/US6372458B1/en not_active Expired - Lifetime
- 2000-04-03 NO NO20001706A patent/NO320096B1/no not_active IP Right Cessation
-
2001
- 2001-04-10 HK HK01102527A patent/HK1031896A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA966433B (en) | Process for the production of high purity carbon dioxide. | |
AU8672098A (en) | Method for the production of lower organic peracids | |
AU4815197A (en) | Tetraphosphonate bicyclic trisanhydrides | |
NO993455L (no) | Prosess for elektrolytisk produksjon av metaller | |
TW200611692A (en) | Processes for preparation of crystalline mycophenolate sodium | |
CA2249061A1 (en) | Protein production process | |
AU587308B2 (en) | Process for the production of synthesis gas | |
AU6432800A (en) | Process for the synthesis of citalopram | |
HUP0004840A2 (hu) | Eljárás kolchikon vegyületeknek a megfelelő 3-glikozil származékokká történő biotranszformációjára | |
AU8211798A (en) | Process for the production of organic isocyanates | |
AU3420099A (en) | Process for the production of purine derivatives and intermediates therefor | |
AU7321900A (en) | Process for the production of aspartyldipeptide ester derivatives, novel intermediates therefor and process for the production of the intermediates | |
IT1285777B1 (it) | Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati | |
AU7727700A (en) | Robust process for the synthesis of polyestercarbonates | |
IL132442A0 (en) | Process for the production of indole derivatives | |
AU2003245663A1 (en) | Process for the enzymatic resolution of 1,3-dioxolane-4-carboxylates | |
PT1307436E (pt) | Processo para a preparacao de derivados de bacatina iii | |
AU4557499A (en) | Production of high purity meta-xylene | |
IT1303824B1 (it) | Procedimento per la produzione di caprolattame di elevata purezza. | |
AU665710B2 (en) | Process for the production of synthesis gas | |
ZA200000578B (en) | Process for the preparation of organic azides. | |
ZA984466B (en) | Process for obtaining quinapril hydrochloride and solvates useful for the isolation and purification of quinapril hydrochloride | |
ZA974765B (en) | Process for the production of gas | |
AU5109600A (en) | Process for the production of 2-pyridylpyridine derivatives | |
AU4010000A (en) | Epimerization reaction for the production of r-fluoxetine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |