HUP0002322A2 - Multivalens vakcinakészítmény kevert hordozóval - Google Patents
Multivalens vakcinakészítmény kevert hordozóvalInfo
- Publication number
- HUP0002322A2 HUP0002322A2 HU0002322A HUP0002322A HUP0002322A2 HU P0002322 A2 HUP0002322 A2 HU P0002322A2 HU 0002322 A HU0002322 A HU 0002322A HU P0002322 A HUP0002322 A HU P0002322A HU P0002322 A2 HUP0002322 A2 HU P0002322A2
- Authority
- HU
- Hungary
- Prior art keywords
- vaccine composition
- multivalent vaccine
- mixed carrier
- polysaccharides
- carrier
- Prior art date
Links
- 229940031348 multivalent vaccine Drugs 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány gyógyászati készítményekre vonatkozik, amelyek patogénágensek, például baktériumok okozta fertőzések megelőzésére vagykezelésére alkalmazhatók, és amelyek immunogénként egy vagy több, egyvagy több patogén ágensből származó poliszacharidot tartalmaznak. Akészítményben a poliszacharidok konjugátum formájában vannak jelen,hordozóproteinhez kapcsoltan. A készítmény legalább két típusúkonjugátumot tartalmaz, amelyek legalább hordozóproteinjeikvonatkozásában különbözőek. Ó
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9706210A FR2763244B1 (fr) | 1997-05-14 | 1997-05-14 | Composition vaccinale multivalente a porteur mixte |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0002322A2 true HUP0002322A2 (hu) | 2000-11-28 |
HUP0002322A3 HUP0002322A3 (en) | 2001-12-28 |
Family
ID=9507086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0002322A HUP0002322A3 (en) | 1997-05-14 | 1998-05-14 | Multivalent vaccine composition with mixed carrier |
Country Status (20)
Country | Link |
---|---|
US (2) | US7862823B1 (hu) |
EP (1) | EP0983087B1 (hu) |
JP (1) | JP2001525815A (hu) |
KR (1) | KR100709628B1 (hu) |
CN (1) | CN1154509C (hu) |
AT (1) | ATE279942T1 (hu) |
AU (1) | AU748716B2 (hu) |
BR (1) | BR9808772A (hu) |
CA (1) | CA2289009C (hu) |
CZ (1) | CZ295272B6 (hu) |
DE (1) | DE69827127T2 (hu) |
ES (1) | ES2227840T3 (hu) |
FR (1) | FR2763244B1 (hu) |
HU (1) | HUP0002322A3 (hu) |
IL (3) | IL132669A0 (hu) |
NO (1) | NO320415B1 (hu) |
NZ (1) | NZ500738A (hu) |
PL (1) | PL189653B1 (hu) |
PT (1) | PT983087E (hu) |
WO (1) | WO1998051339A1 (hu) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1034792A1 (en) * | 1999-03-11 | 2000-09-13 | Pasteur Merieux Serums Et Vaccins | Intranasal delivery of pneumococcal polysaccharide vaccines |
CN100339130C (zh) * | 1999-03-19 | 2007-09-26 | 史密丝克莱恩比彻姆生物有限公司 | 疫苗 |
GB9909077D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
FR2806304B1 (fr) * | 2000-03-17 | 2002-05-10 | Aventis Pasteur | Conjugues polysaccharidiques du pneumocoque a usage vaccinal contre le tetanos et la diphterie |
GB0108364D0 (en) * | 2001-04-03 | 2001-05-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0130215D0 (en) * | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
FR2850106B1 (fr) | 2003-01-17 | 2005-02-25 | Aventis Pasteur | Conjugues obtenus par amination reductrice du polysaccharide capsulaire du pneumocoque de serotype 5 |
GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
BRPI0510315A (pt) | 2004-04-30 | 2007-10-16 | Chiron Srl | integração de vacinação com conjugado meningocócico |
GB0419846D0 (en) * | 2004-09-07 | 2004-10-13 | Chiron Srl | Vaccine adjuvants for saccharides |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US20070184072A1 (en) | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
EP2425856A1 (en) | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent pneumococcal polysaccharide-protein conjugate composition |
HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
JP5135220B2 (ja) | 2005-09-01 | 2013-02-06 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー | 血清群c髄膜炎菌を含む複数ワクチン接種 |
MY150719A (en) | 2005-12-22 | 2014-02-28 | Glaxosmithkline Biolog Sa | Pneumococcal polysaccharide conjugate vaccine |
TW200806315A (en) | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
AU2008248640A1 (en) | 2007-05-02 | 2008-11-13 | Glaxosmithkline Biologicals S.A. | Vaccine |
EP2170391B1 (en) * | 2007-06-20 | 2017-01-18 | Pfizer Ireland Pharmaceuticals | Modified polysaccharides for conjugate vaccines |
US9610340B2 (en) | 2007-06-26 | 2017-04-04 | Glaxosmithkline Biologicals, S.A. | Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates |
US20130071422A1 (en) | 2010-03-18 | 2013-03-21 | Michele Pallaoro | Adjuvanted vaccines for serogroup b meningococcus |
BR112013005049A2 (pt) | 2010-09-02 | 2016-05-31 | Sanofi Pasteur | estabilizador para a preparação de uma composição vacina da pólio seca injetável |
GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
HUE040914T4 (hu) * | 2012-01-30 | 2019-05-28 | Serum Institute Of India Pvt Ltd | Immunogén készítmény |
ES2773954T3 (es) | 2012-10-03 | 2020-07-15 | Glaxosmithkline Biologicals Sa | Composición inmunogénica |
WO2016012385A1 (en) | 2014-07-21 | 2016-01-28 | Sanofi Pasteur | Vaccine composition comprising ipv and cyclodextrins |
US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
CN105695497B (zh) | 2014-11-27 | 2019-09-24 | 中国人民解放军军事医学科学院生物工程研究所 | 一种细菌多糖修饰的重组融合蛋白的制备方法及其应用 |
AU2016285017B2 (en) | 2015-06-23 | 2022-03-03 | Biological E Limited | Multivalent pneumococcal conjugate vaccine |
WO2018027126A1 (en) * | 2016-08-05 | 2018-02-08 | Sanofi Pasteur, Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
CA3031797A1 (en) * | 2016-08-05 | 2018-02-08 | Sanofi Pasteur, Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
CA3037056A1 (en) | 2016-09-30 | 2018-04-05 | Biological E Limited | Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
CA3048981A1 (en) | 2016-12-30 | 2018-07-05 | Sutrovax, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
WO2018227177A1 (en) | 2017-06-10 | 2018-12-13 | Inventprise, Llc | Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
CA3087572A1 (en) * | 2018-02-05 | 2019-08-08 | Sanofi Pasteur Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
JP6950099B2 (ja) | 2018-02-05 | 2021-10-13 | サノフィ パスツール インコーポレイティッド | 多価肺炎球菌多糖体−タンパク質複合体組成物 |
JP2021522213A (ja) | 2018-04-18 | 2021-08-30 | エスケー バイオサイエンス カンパニー リミテッド | ストレプトコッカス・ニューモニエ莢膜多糖類及びその免疫原性接合体 |
JP7399934B2 (ja) | 2018-07-04 | 2023-12-18 | バックスサイト・インコーポレイテッド | 免疫原性複合体の改良 |
WO2020010016A1 (en) | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Self-adjuvanted immunogenic conjugates |
WO2023200704A1 (en) | 2022-04-11 | 2023-10-19 | Sanofi Pasteur Inc. | Protein-saccharide conjugation with sodium cyanoborohydride |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5639022A (en) * | 1979-09-05 | 1981-04-14 | Hayashibara Biochem Lab Inc | Preparation of vaccine |
NZ220932A (en) * | 1986-07-03 | 1990-05-28 | Victoria State | Composition comprising an antigenic substance, such as lhrh, conjugated to at least two different carriers and method of immunological castration and spaying |
CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
CN100339130C (zh) | 1999-03-19 | 2007-09-26 | 史密丝克莱恩比彻姆生物有限公司 | 疫苗 |
GB0130215D0 (en) | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
-
1997
- 1997-05-14 FR FR9706210A patent/FR2763244B1/fr not_active Expired - Lifetime
-
1998
- 1998-05-14 JP JP54887698A patent/JP2001525815A/ja active Pending
- 1998-05-14 BR BR9808772-0A patent/BR9808772A/pt not_active Application Discontinuation
- 1998-05-14 KR KR1019997010432A patent/KR100709628B1/ko not_active IP Right Cessation
- 1998-05-14 PL PL98336704A patent/PL189653B1/pl unknown
- 1998-05-14 DE DE69827127T patent/DE69827127T2/de not_active Revoked
- 1998-05-14 WO PCT/FR1998/000966 patent/WO1998051339A1/fr active Application Filing
- 1998-05-14 AT AT98925715T patent/ATE279942T1/de not_active IP Right Cessation
- 1998-05-14 HU HU0002322A patent/HUP0002322A3/hu unknown
- 1998-05-14 EP EP98925715A patent/EP0983087B1/fr not_active Revoked
- 1998-05-14 CA CA2289009A patent/CA2289009C/fr not_active Expired - Fee Related
- 1998-05-14 IL IL13266998A patent/IL132669A0/xx unknown
- 1998-05-14 US US09/423,698 patent/US7862823B1/en not_active Expired - Fee Related
- 1998-05-14 CN CNB988050765A patent/CN1154509C/zh not_active Expired - Fee Related
- 1998-05-14 PT PT98925715T patent/PT983087E/pt unknown
- 1998-05-14 NZ NZ500738A patent/NZ500738A/en not_active IP Right Cessation
- 1998-05-14 ES ES98925715T patent/ES2227840T3/es not_active Expired - Lifetime
- 1998-05-14 CZ CZ19994021A patent/CZ295272B6/cs not_active IP Right Cessation
- 1998-05-14 AU AU77730/98A patent/AU748716B2/en not_active Ceased
-
1999
- 1999-11-01 IL IL132669A patent/IL132669A/en not_active IP Right Cessation
- 1999-11-02 NO NO19995349A patent/NO320415B1/no not_active IP Right Cessation
-
2007
- 2007-05-17 IL IL183296A patent/IL183296A0/en unknown
-
2010
- 2010-11-22 US US12/951,867 patent/US8029798B2/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: SANOFI PASTEUR, FR Free format text: FORMER OWNER(S): PASTEUR MERIEUX SERUMS & VACCINS, FR; AVENTIS PASTEUR, FR |
|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |