HUE038878T2 - Aminotriazolopirimidin gyulladás kezelésében történõ alkalmazásra és gyógyászati készítményeik - Google Patents

Aminotriazolopirimidin gyulladás kezelésében történõ alkalmazásra és gyógyászati készítményeik

Info

Publication number: HUE038878T2
Authority: HU; Hungary
Prior art keywords: aminotriazolopyridine; inflammation; treatment; pharmaceutical compositions; pharmaceutical
Prior art date: 2012-06-22

Application number

HUE13727625A

Other languages

English (en)

Inventor

't Klooster Gerben Albert Eleutherius Van

Reginald Christophe Xavier Brys

Rompaey Luc Juliaan Corina Van

Florence Sylvie Namour

Original Assignee

Galapagos Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-06-22

Filing date

2013-06-10

Publication date

2018-12-28

2013-06-10 Application filed by Galapagos Nv filed Critical Galapagos Nv

2018-12-28 Publication of HUE038878T2 publication Critical patent/HUE038878T2/hu

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

HUE13727625A 2012-06-22 2013-06-10 Aminotriazolopirimidin gyulladás kezelésében történõ alkalmazásra és gyógyászati készítményeik HUE038878T2 (hu)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201261663520P	2012-06-22	2012-06-22

Publications (1)

Publication Number	Publication Date
HUE038878T2 true HUE038878T2 (hu)	2018-12-28

Family

ID=48577773

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HUE13727625A HUE038878T2 (hu)	2012-06-22	2013-06-10	Aminotriazolopirimidin gyulladás kezelésében történõ alkalmazásra és gyógyászati készítményeik

Country Status (35)

Country	Link
US (2)	US9284311B2 (hu)
EP (1)	EP2863950B1 (hu)
JP (2)	JP6238975B2 (hu)
KR (1)	KR102078069B1 (hu)
CN (2)	CN104379173A (hu)
AR (1)	AR091395A1 (hu)
AU (1)	AU2013279597B2 (hu)
BR (1)	BR112014031626A8 (hu)
CA (1)	CA2875619C (hu)
CL (1)	CL2014003462A1 (hu)
CO (1)	CO7160085A2 (hu)
CR (1)	CR20140583A (hu)
CY (1)	CY1120643T1 (hu)
DK (1)	DK2863950T3 (hu)
EA (1)	EA029084B1 (hu)
ES (1)	ES2685985T3 (hu)
HK (1)	HK1208368A1 (hu)
HR (1)	HRP20181364T8 (hu)
HU (1)	HUE038878T2 (hu)
IL (1)	IL235923B (hu)
LT (1)	LT2863950T (hu)
MA (1)	MA37775A1 (hu)
MX (1)	MX368511B (hu)
MY (1)	MY177334A (hu)
NZ (1)	NZ702480A (hu)
PE (1)	PE20150187A1 (hu)
PH (1)	PH12014502615A1 (hu)
PL (1)	PL2863950T3 (hu)
PT (1)	PT2863950T (hu)
SG (2)	SG11201408123SA (hu)
SI (1)	SI2863950T1 (hu)
TW (1)	TWI586352B (hu)
UA (1)	UA112804C2 (hu)
UY (1)	UY34855A (hu)
WO (1)	WO2013189771A1 (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JO3041B1 (ar)	2008-07-25	2016-09-05	Galapagos Nv	مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
TWI462920B (zh)	2009-06-26	2014-12-01	葛萊伯格有限公司	用於治療退化性及發炎疾病之新穎化合物
GB201402071D0 (en) *	2014-02-07	2014-03-26	Galapagos Nv	Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201402070D0 (en)	2014-02-07	2014-03-26	Galapagos Nv	Pharmaceutical compositions for the treatment of inflammatory disorders
WO2016165953A1 (en)	2015-04-13	2016-10-20	Galapagos Nv	Methods for the treatment of inflammatory disorders
US10376520B2 (en) *	2015-04-13	2019-08-13	Galapagos Nv	Methods for the treatment of cardiovascular disorders
WO2016179207A1 (en) *	2015-05-05	2016-11-10	Concert Pharmaceuticals, Inc.	Deuterated filgotinib
CN105061420B (zh) *	2015-06-04	2017-09-05	南京旗昌医药科技有限公司	一种jak抑制剂的晶型及其制备方法和应用
WO2017106568A1 (en)	2015-12-17	2017-06-22	Gilead Sciences, Inc.	Combination of a jak inhibitor and a bromodomain inhibitor for treating cancer
US20170173034A1 (en)	2015-12-17	2017-06-22	Gilead Sciences, Inc.	Combination of a jak inhibitor and a syk inhibitor for treating cancers and inflammatory disorders
WO2017106566A1 (en)	2015-12-17	2017-06-22	Gilead Sciences, Inc.	Combination of a jak inhibitor and an mmp9 binding protein for treating inflammatory disorders
CN108349974B (zh) *	2016-02-02	2021-04-30	深圳市塔吉瑞生物医药有限公司	一种取代的吡啶酰胺类化合物及其应用
CA3043396A1 (en)	2016-11-10	2018-05-17	Galapagos Nv	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory diseases
GB201702603D0 (en)	2017-02-17	2017-04-05	Galápagos Nv	Novel compositions and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201808575D0 (en) *	2018-05-24	2018-07-11	Galapagos Nv	Methods for the treatment of psoriatic arthrits
WO2019246273A1 (en)	2018-06-20	2019-12-26	Progenity, Inc.	Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor
US20220185810A1 (en) *	2019-03-30	2022-06-16	Unichem Laboratories Limited	Novel Process for the Preparation of Filgotinib and Intermediates Thereof
JP7315166B2 (ja) *	2019-06-10	2023-07-26	富士通株式会社	グラフェンナノリボンネットワーク膜の製造方法及び電子装置の製造方法
CN111686106B (zh) *	2020-04-05	2022-07-15	温州医科大学附属第一医院	提高Dicer表达的化合物在制备药物中的应用
CN114409675B (zh) *	2022-01-07	2023-08-04	重庆医科大学	螺环异恶唑酮色满衍生物在制备用于治疗jak1介导的疾病药物中的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2662074A1 (en) *	2006-08-30	2008-03-06	Cellzome Limited	Triazole derivatives as kinase inhibitors
TWI453207B (zh) *	2008-09-08	2014-09-21	Signal Pharm Llc	胺基***并吡啶，其組合物及使用其之治療方法
MX2011012961A (es)	2009-06-05	2012-01-30	Cephalon Inc	Preparacion y usos de derivados de 1,2,4-triazolo[1,5a]-piridina.
TWI462920B (zh) *	2009-06-26	2014-12-01	葛萊伯格有限公司	用於治療退化性及發炎疾病之新穎化合物
JO3030B1 (ar) *	2009-06-26	2016-09-05	Galapagos Nv	مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات

2013
- 2013-06-10 SI SI201331137T patent/SI2863950T1/sl unknown
- 2013-06-10 WO PCT/EP2013/061914 patent/WO2013189771A1/en active Application Filing
- 2013-06-10 PT PT13727625T patent/PT2863950T/pt unknown
- 2013-06-10 AR ARP130102033 patent/AR091395A1/es unknown
- 2013-06-10 PE PE2014002472A patent/PE20150187A1/es not_active Application Discontinuation
- 2013-06-10 NZ NZ702480A patent/NZ702480A/en unknown
- 2013-06-10 LT LTEP13727625.9T patent/LT2863950T/lt unknown
- 2013-06-10 CN CN201380032159.5A patent/CN104379173A/zh active Pending
- 2013-06-10 JP JP2015517666A patent/JP6238975B2/ja active Active
- 2013-06-10 SG SG11201408123SA patent/SG11201408123SA/en unknown
- 2013-06-10 MY MYPI2014703876A patent/MY177334A/en unknown
- 2013-06-10 HU HUE13727625A patent/HUE038878T2/hu unknown
- 2013-06-10 KR KR1020157001521A patent/KR102078069B1/ko active IP Right Grant
- 2013-06-10 ES ES13727625.9T patent/ES2685985T3/es active Active
- 2013-06-10 DK DK13727625.9T patent/DK2863950T3/en active
- 2013-06-10 CA CA2875619A patent/CA2875619C/en active Active
- 2013-06-10 PL PL13727625T patent/PL2863950T3/pl unknown
- 2013-06-10 AU AU2013279597A patent/AU2013279597B2/en active Active
- 2013-06-10 EP EP13727625.9A patent/EP2863950B1/en active Active
- 2013-06-10 CN CN201810014031.0A patent/CN107998136A/zh active Pending
- 2013-06-10 EA EA201590071A patent/EA029084B1/ru unknown
- 2013-06-10 SG SG10201700125VA patent/SG10201700125VA/en unknown
- 2013-06-10 MX MX2014014800A patent/MX368511B/es active IP Right Grant
- 2013-06-10 BR BR112014031626A patent/BR112014031626A8/pt not_active Application Discontinuation
- 2013-06-10 UY UY0001034855A patent/UY34855A/es unknown
- 2013-06-10 US US13/913,597 patent/US9284311B2/en active Active
- 2013-06-10 MA MA37775A patent/MA37775A1/fr unknown
- 2013-06-11 TW TW102120793A patent/TWI586352B/zh active
- 2013-10-06 UA UAA201500458A patent/UA112804C2/uk unknown
2014
- 2014-11-24 PH PH12014502615A patent/PH12014502615A1/en unknown
- 2014-11-26 IL IL235923A patent/IL235923B/en active IP Right Grant
- 2014-12-16 CR CR20140583A patent/CR20140583A/es unknown
- 2014-12-19 CL CL2014003462A patent/CL2014003462A1/es unknown
- 2014-12-19 CO CO14279834A patent/CO7160085A2/es unknown
2015
- 2015-09-17 HK HK15109111.8A patent/HK1208368A1/xx unknown
2016
- 2016-03-14 US US15/069,130 patent/US20160296529A1/en not_active Abandoned
2017
- 2017-10-31 JP JP2017210372A patent/JP2018048185A/ja active Pending
2018
- 2018-08-27 HR HRP20181364TT patent/HRP20181364T8/hr unknown
- 2018-08-29 CY CY181100902T patent/CY1120643T1/el unknown

Also Published As

Publication number	Publication date
CA2875619C (en)	2020-11-24
SG10201700125VA (en)	2017-02-27
CR20140583A (es)	2015-02-10
EP2863950A1 (en)	2015-04-29
US20160296529A1 (en)	2016-10-13
EP2863950B1 (en)	2018-07-18
CA2875619A1 (en)	2013-12-27
SI2863950T1 (sl)	2018-10-30
LT2863950T (lt)	2018-09-25
BR112014031626A8 (pt)	2021-10-19
MY177334A (en)	2020-09-12
JP2015520198A (ja)	2015-07-16
AU2013279597B2 (en)	2017-04-20
PT2863950T (pt)	2018-10-10
DK2863950T3 (en)	2018-09-03
PH12014502615B1 (en)	2015-01-21
CN107998136A (zh)	2018-05-08
PL2863950T3 (pl)	2019-02-28
WO2013189771A1 (en)	2013-12-27
BR112014031626A2 (pt)	2017-06-27
AU2013279597A1 (en)	2015-01-15
MX2014014800A (es)	2015-02-12
PE20150187A1 (es)	2015-02-27
TW201400114A (zh)	2014-01-01
ES2685985T3 (es)	2018-10-15
CL2014003462A1 (es)	2015-02-27
NZ702480A (en)	2016-11-25
PH12014502615A1 (en)	2015-01-21
EA029084B1 (ru)	2018-02-28
CN104379173A (zh)	2015-02-25
HK1208368A1 (en)	2016-03-04
SG11201408123SA (en)	2015-01-29
CO7160085A2 (es)	2015-01-15
UY34855A (es)	2014-01-31
US20130345209A1 (en)	2013-12-26
UA112804C2 (uk)	2016-10-25
MA37775A1 (fr)	2017-04-28
HRP20181364T8 (hr)	2018-12-28
AR091395A1 (es)	2015-02-04
IL235923B (en)	2018-11-29
CY1120643T1 (el)	2019-12-11
JP6238975B2 (ja)	2017-11-29
KR20150023048A (ko)	2015-03-04
HRP20181364T1 (hr)	2018-10-19
JP2018048185A (ja)	2018-03-29
IL235923A0 (en)	2015-01-29
US9284311B2 (en)	2016-03-15
KR102078069B1 (ko)	2020-02-17
MX368511B (es)	2019-10-07
TWI586352B (zh)	2017-06-11
EA201590071A1 (ru)	2015-04-30

Publication	Publication Date	Title
HRP20181364T1 (hr)	2018-10-19	Aminotriazolopiridin, namijenjen upotrebi u liječenju upale, te njegovi farmacetski pripravci
IL231536A (en)	2016-09-29	Indazole-3-carboxamides, pharmaceuticals containing them and their use in the treatment of diseases
HK1205690A1 (en)	2015-12-24	Pharmaceutical composition and administration thereof
IL252566A0 (en)	2017-07-31	Pharmacy preparations and methods
IL236221A (en)	2017-12-31	History of theophyridone and pharmacological preparations containing them for the treatment of diseases
HK1199712A1 (en)	2015-07-17	18-methyl-6,7-methylene-3-oxo-17-pregn-4-ene-21,17-carbolactones, pharmaceutical preparations comprising said compounds and use thereof in the treatment of endometriosis 18--67--3--17--4--2117-
HK1202415A1 (en)	2015-10-02	Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15- hetre and methods of use thereof dgla15-ohepa/ 15-hetre
IL237125A0 (en)	2015-03-31	Use of preparations containing niclosamide and/or its derivatives for the treatment of solid tumors
HK1203947A1 (en)	2015-11-06	Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions (halofuginol)
IL244901A0 (en)	2016-05-31	Derivatives of aminotetralin and aminoindan, pharmaceutical compositions containing them and their use in therapy
GB201222455D0 (en)	2013-01-30	Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
HK1203050A1 (en)	2015-10-16	Novel dosage and formulation
HK1197235A1 (zh)	2015-01-09	二氫吡唑、其藥物組合物及其治療生育障礙的用途
IL233875A (en)	2017-01-31	Preparation and use for the treatment of anal fissures
GB2504390B (en)	2015-06-03	Nutraceutical and pharmaceutical composition
EP2685993A4 (en)	2014-11-19	PHARMACEUTICAL COMPOSITIONS AND TOPICAL USE THEREOF
EP2854786A4 (en)	2015-11-11	PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INFLAMMATION AND PAIN
HK1204556A1 (zh)	2015-11-27	藥物組合物及使用該藥物組合物的準藥物化妝品
EP2854785A4 (en)	2016-02-10	PHARMACEUTICAL COMPOSITION FOR TREATING INFLAMMATION AND PAIN
PL2854748T3 (pl)	2018-01-31	Kompozycja farmaceutyczna do leczenia zapalenia skóry i powiązanych syndromów
EP2926811A4 (en)	2016-08-03	ARTEMISCULAR PHARMACEUTICAL COMPOSITION, MANUFACTURE AND USE
GB201208315D0 (en)	2012-06-27	Pharmaceutical methods and compositions
ZA201503799B (en)	2016-02-24	Fixed dose pharmaceutical composition comprising mometasone and azelastine
ZA201404052B (en)	2016-05-25	18-methyl-6,7-methylene-3-oxo-17-pregn-4-ene-21,17b-carbolactones, pharmaceutical preparations comprising said compounds and use thereof in treatment of endometriosis
GB201207064D0 (en)	2012-06-06	Pharmaceutical compositions comprising 15-hetre and methods of using the same