CR20140583A - Aminotriazolopirimidina para uso en tratamiento de inflamación y composiciones farmacéuticas de la misma - Google Patents
Aminotriazolopirimidina para uso en tratamiento de inflamación y composiciones farmacéuticas de la mismaInfo
- Publication number
- CR20140583A CR20140583A CR20140583A CR20140583A CR20140583A CR 20140583 A CR20140583 A CR 20140583A CR 20140583 A CR20140583 A CR 20140583A CR 20140583 A CR20140583 A CR 20140583A CR 20140583 A CR20140583 A CR 20140583A
- Authority
- CR
- Costa Rica
- Prior art keywords
- treatment
- aminotriazolopirimidine
- inflammation
- same
- pharmaceutical compositions
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
La presente invención se refiere al nuevo uso médico del compuesto de conformidad con la Fórmula I, en particular en el tratamiento de afecciones inflamatorias, enfermedades autoinmunitarias, enfermedades proliferativas, alergias, rechazo de trasplante, enfermedades que implican in deterioro de la producción de cartílago y/o enfermedades asociadas con la hipersecreción de IL6 o interferones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261663520P | 2012-06-22 | 2012-06-22 | |
PCT/EP2013/061914 WO2013189771A1 (en) | 2012-06-22 | 2013-06-10 | Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20140583A true CR20140583A (es) | 2015-02-10 |
Family
ID=48577773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20140583A CR20140583A (es) | 2012-06-22 | 2014-12-16 | Aminotriazolopirimidina para uso en tratamiento de inflamación y composiciones farmacéuticas de la misma |
Country Status (35)
Country | Link |
---|---|
US (2) | US9284311B2 (es) |
EP (1) | EP2863950B1 (es) |
JP (2) | JP6238975B2 (es) |
KR (1) | KR102078069B1 (es) |
CN (2) | CN104379173A (es) |
AR (1) | AR091395A1 (es) |
AU (1) | AU2013279597B2 (es) |
BR (1) | BR112014031626A8 (es) |
CA (1) | CA2875619C (es) |
CL (1) | CL2014003462A1 (es) |
CO (1) | CO7160085A2 (es) |
CR (1) | CR20140583A (es) |
CY (1) | CY1120643T1 (es) |
DK (1) | DK2863950T3 (es) |
EA (1) | EA029084B1 (es) |
ES (1) | ES2685985T3 (es) |
HK (1) | HK1208368A1 (es) |
HR (1) | HRP20181364T8 (es) |
HU (1) | HUE038878T2 (es) |
IL (1) | IL235923B (es) |
LT (1) | LT2863950T (es) |
MA (1) | MA37775A1 (es) |
MX (1) | MX368511B (es) |
MY (1) | MY177334A (es) |
NZ (1) | NZ702480A (es) |
PE (1) | PE20150187A1 (es) |
PH (1) | PH12014502615B1 (es) |
PL (1) | PL2863950T3 (es) |
PT (1) | PT2863950T (es) |
SG (2) | SG10201700125VA (es) |
SI (1) | SI2863950T1 (es) |
TW (1) | TWI586352B (es) |
UA (1) | UA112804C2 (es) |
UY (1) | UY34855A (es) |
WO (1) | WO2013189771A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO3041B1 (ar) | 2008-07-25 | 2016-09-05 | Galapagos Nv | مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية |
TWI462920B (zh) | 2009-06-26 | 2014-12-01 | 葛萊伯格有限公司 | 用於治療退化性及發炎疾病之新穎化合物 |
GB201402070D0 (en) | 2014-02-07 | 2014-03-26 | Galapagos Nv | Pharmaceutical compositions for the treatment of inflammatory disorders |
GB201402071D0 (en) * | 2014-02-07 | 2014-03-26 | Galapagos Nv | Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
WO2016165952A1 (en) * | 2015-04-13 | 2016-10-20 | Galapagos Nv | Methods for the treatment of cardiovascular disorders |
EP3283078A1 (en) * | 2015-04-13 | 2018-02-21 | Galapagos NV | Methods for the treatment of inflammatory disorders |
AU2016257892A1 (en) * | 2015-05-05 | 2017-11-09 | Concert Pharmaceuticals, Inc. | Deuterated filgotinib |
CN105061420B (zh) * | 2015-06-04 | 2017-09-05 | 南京旗昌医药科技有限公司 | 一种jak抑制剂的晶型及其制备方法和应用 |
WO2017106568A1 (en) | 2015-12-17 | 2017-06-22 | Gilead Sciences, Inc. | Combination of a jak inhibitor and a bromodomain inhibitor for treating cancer |
WO2017106564A1 (en) | 2015-12-17 | 2017-06-22 | Gilead Sciences, Inc. | Combination of a jak inhibitor and a syk inhibitor for treating cancers and inflammatory disorders |
US20170174788A1 (en) | 2015-12-17 | 2017-06-22 | Gilead Sciences, Inc. | Combination of a jak inhibitor and an mmp9 binding protein for treating inflammatory disorders |
CN112851682B (zh) * | 2016-02-02 | 2022-10-25 | 深圳市塔吉瑞生物医药有限公司 | 一种取代的吡啶酰胺类化合物及其应用 |
EP3538103A1 (en) | 2016-11-10 | 2019-09-18 | Galapagos NV | Compounds and pharmaceutical compositions thereof for the treatment of inflammatory diseases |
GB201702603D0 (en) | 2017-02-17 | 2017-04-05 | Galápagos Nv | Novel compositions and pharmaceutical compositions thereof for the treatment of inflammatory disorders |
GB201808575D0 (en) * | 2018-05-24 | 2018-07-11 | Galapagos Nv | Methods for the treatment of psoriatic arthrits |
US20220257600A1 (en) | 2018-06-20 | 2022-08-18 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor |
MX2021011548A (es) * | 2019-03-30 | 2021-10-22 | Unichem Lab Ltd | Proceso novedoso para la preparacion de filgotinib e intermediarios del mismo. |
JP7315166B2 (ja) * | 2019-06-10 | 2023-07-26 | 富士通株式会社 | グラフェンナノリボンネットワーク膜の製造方法及び電子装置の製造方法 |
CN111686106B (zh) * | 2020-04-05 | 2022-07-15 | 温州医科大学附属第一医院 | 提高Dicer表达的化合物在制备药物中的应用 |
CN114409675B (zh) * | 2022-01-07 | 2023-08-04 | 重庆医科大学 | 螺环异恶唑酮色满衍生物在制备用于治疗jak1介导的疾病药物中的用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG174086A1 (en) * | 2006-08-30 | 2011-09-29 | Cellzome Ltd | Triazole derivatives as kinase inhibitors |
TWI453207B (zh) * | 2008-09-08 | 2014-09-21 | Signal Pharm Llc | 胺基***并吡啶,其組合物及使用其之治療方法 |
EP2438066A2 (en) * | 2009-06-05 | 2012-04-11 | Cephalon, Inc. | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a]PYRIDINE DERIVATIVES |
TWI462920B (zh) * | 2009-06-26 | 2014-12-01 | 葛萊伯格有限公司 | 用於治療退化性及發炎疾病之新穎化合物 |
JO3030B1 (ar) * | 2009-06-26 | 2016-09-05 | Galapagos Nv | مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات |
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2013
- 2013-06-10 PL PL13727625T patent/PL2863950T3/pl unknown
- 2013-06-10 NZ NZ702480A patent/NZ702480A/en unknown
- 2013-06-10 SI SI201331137T patent/SI2863950T1/sl unknown
- 2013-06-10 MX MX2014014800A patent/MX368511B/es active IP Right Grant
- 2013-06-10 LT LTEP13727625.9T patent/LT2863950T/lt unknown
- 2013-06-10 ES ES13727625.9T patent/ES2685985T3/es active Active
- 2013-06-10 SG SG10201700125VA patent/SG10201700125VA/en unknown
- 2013-06-10 JP JP2015517666A patent/JP6238975B2/ja active Active
- 2013-06-10 HU HUE13727625A patent/HUE038878T2/hu unknown
- 2013-06-10 AR ARP130102033 patent/AR091395A1/es unknown
- 2013-06-10 KR KR1020157001521A patent/KR102078069B1/ko active IP Right Grant
- 2013-06-10 CA CA2875619A patent/CA2875619C/en active Active
- 2013-06-10 CN CN201380032159.5A patent/CN104379173A/zh active Pending
- 2013-06-10 PT PT13727625T patent/PT2863950T/pt unknown
- 2013-06-10 CN CN201810014031.0A patent/CN107998136A/zh active Pending
- 2013-06-10 UY UY0001034855A patent/UY34855A/es unknown
- 2013-06-10 BR BR112014031626A patent/BR112014031626A8/pt not_active Application Discontinuation
- 2013-06-10 AU AU2013279597A patent/AU2013279597B2/en active Active
- 2013-06-10 MA MA37775A patent/MA37775A1/fr unknown
- 2013-06-10 WO PCT/EP2013/061914 patent/WO2013189771A1/en active Application Filing
- 2013-06-10 EP EP13727625.9A patent/EP2863950B1/en active Active
- 2013-06-10 US US13/913,597 patent/US9284311B2/en active Active
- 2013-06-10 MY MYPI2014703876A patent/MY177334A/en unknown
- 2013-06-10 PE PE2014002472A patent/PE20150187A1/es not_active Application Discontinuation
- 2013-06-10 SG SG11201408123SA patent/SG11201408123SA/en unknown
- 2013-06-10 EA EA201590071A patent/EA029084B1/ru unknown
- 2013-06-10 DK DK13727625.9T patent/DK2863950T3/en active
- 2013-06-11 TW TW102120793A patent/TWI586352B/zh active
- 2013-10-06 UA UAA201500458A patent/UA112804C2/uk unknown
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2014
- 2014-11-24 PH PH12014502615A patent/PH12014502615B1/en unknown
- 2014-11-26 IL IL235923A patent/IL235923B/en active IP Right Grant
- 2014-12-16 CR CR20140583A patent/CR20140583A/es unknown
- 2014-12-19 CO CO14279834A patent/CO7160085A2/es unknown
- 2014-12-19 CL CL2014003462A patent/CL2014003462A1/es unknown
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2015
- 2015-09-17 HK HK15109111.8A patent/HK1208368A1/xx unknown
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2016
- 2016-03-14 US US15/069,130 patent/US20160296529A1/en not_active Abandoned
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2017
- 2017-10-31 JP JP2017210372A patent/JP2018048185A/ja active Pending
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2018
- 2018-08-27 HR HRP20181364TT patent/HRP20181364T8/hr unknown
- 2018-08-29 CY CY181100902T patent/CY1120643T1/el unknown
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