HU206712B - Process for producing new 17-aza-20,21-dinor-eburnamenin derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing new 17-aza-20,21-dinor-eburnamenin derivatives and pharmaceutical compositions containing them

Info

Publication number
HU206712B
HU206712B HU881921A HU192188A HU206712B HU 206712 B HU206712 B HU 206712B HU 881921 A HU881921 A HU 881921A HU 192188 A HU192188 A HU 192188A HU 206712 B HU206712 B HU 206712B
Authority
HU
Hungary
Prior art keywords
image
carbon atoms
group
alkyl
eburnamenin
Prior art date
Application number
HU881921A
Other languages
English (en)
Other versions
HUT46326A (en
Inventor
Norguen Aktogu
Francois Clemence
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of HUT46326A publication Critical patent/HUT46326A/hu
Publication of HU206712B publication Critical patent/HU206712B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU881921A 1987-04-15 1988-04-14 Process for producing new 17-aza-20,21-dinor-eburnamenin derivatives and pharmaceutical compositions containing them HU206712B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8705361A FR2614022B1 (fr) 1987-04-15 1987-04-15 Nouveaux derives 17-aza de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et ces compositions les renfermant

Publications (2)

Publication Number Publication Date
HUT46326A HUT46326A (en) 1988-10-28
HU206712B true HU206712B (en) 1992-12-28

Family

ID=9350164

Family Applications (1)

Application Number Title Priority Date Filing Date
HU881921A HU206712B (en) 1987-04-15 1988-04-14 Process for producing new 17-aza-20,21-dinor-eburnamenin derivatives and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US4886802A (hu)
EP (1) EP0287468B1 (hu)
JP (1) JPS63295576A (hu)
AT (1) ATE86624T1 (hu)
CA (1) CA1324793C (hu)
DE (1) DE3878967T2 (hu)
ES (1) ES2053780T3 (hu)
FR (1) FR2614022B1 (hu)
GR (1) GR3007599T3 (hu)
HU (1) HU206712B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496957A (en) * 1993-09-01 1996-03-05 Virginia Commonwealth University Tryptamine analogs with 5-HT1D selectivity
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2713643B1 (fr) * 1993-12-14 1996-06-07 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5504101A (en) * 1994-05-06 1996-04-02 Allelix Biopharmaceuticals, Inc. 5-HT-1D receptor ligands
GB2296170A (en) * 1994-12-16 1996-06-19 Ibm Audio communication apparatus
DE10254596A1 (de) * 2002-11-22 2004-06-03 Merck Patent Gmbh Indolderivate
FR2926077A1 (fr) 2008-01-04 2009-07-10 Servier Lab Nouveaux derives d'1h-indol-1-yl uree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2168853B1 (hu) * 1972-01-24 1975-04-25 Centre Etd Ind Pharma
US3843653A (en) * 1972-11-06 1974-10-22 Du Pont 5,6,12,13-di-isoquino-(4,3-b:4',3'-e)-pyrazine-5,12-diones

Also Published As

Publication number Publication date
ATE86624T1 (de) 1993-03-15
EP0287468A2 (fr) 1988-10-19
US4886802A (en) 1989-12-12
FR2614022B1 (fr) 1989-12-01
DE3878967D1 (de) 1993-04-15
JPS63295576A (ja) 1988-12-01
EP0287468A3 (en) 1990-05-02
CA1324793C (fr) 1993-11-30
ES2053780T3 (es) 1994-08-01
EP0287468B1 (fr) 1993-03-10
DE3878967T2 (de) 1993-08-19
HUT46326A (en) 1988-10-28
FR2614022A1 (fr) 1988-10-21
GR3007599T3 (hu) 1993-08-31

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