HRP20230336T1 - Sastavi protiv krvarenja - Google Patents
Sastavi protiv krvarenja Download PDFInfo
- Publication number
- HRP20230336T1 HRP20230336T1 HRP20230336TT HRP20230336T HRP20230336T1 HR P20230336 T1 HRP20230336 T1 HR P20230336T1 HR P20230336T T HRP20230336T T HR P20230336TT HR P20230336 T HRP20230336 T HR P20230336T HR P20230336 T1 HRP20230336 T1 HR P20230336T1
- Authority
- HR
- Croatia
- Prior art keywords
- composition
- use according
- calcium carbonate
- blood
- blood vessel
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 17
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 24
- 229910000019 calcium carbonate Inorganic materials 0.000 claims 12
- 239000000463 material Substances 0.000 claims 8
- 210000004204 blood vessel Anatomy 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 5
- 230000023555 blood coagulation Effects 0.000 claims 4
- 230000000740 bleeding effect Effects 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 150000001860 citric acid derivatives Chemical class 0.000 claims 2
- 230000006698 induction Effects 0.000 claims 2
- 239000011236 particulate material Substances 0.000 claims 2
- 208000007536 Thrombosis Diseases 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000006208 topical dosage form Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/614—Cnidaria, e.g. sea anemones, corals, coral animals or jellyfish
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Confectionery (AREA)
Claims (15)
1. Sastav za izazivanje koagulacije krvi koji sadrži citratnu sol i materijal koji sadrži kalcijev karbonat, sastav koji je za upotrebu u smanjenju ili zaustavljanju krvarenja kod subjekta kojem je to potrebno.
2. Sastav za upotrebu prema patentnom zahtjevu 1, pri čemu materijal koji sadrži kalcijev karbonat sadrži kristalni kalcijev karbonat.
3. Sastav za upotrebu prema patentnom zahtjevu 1, pri čemu materijal koji sadrži kalcijev karbonat sadrži amorfni kalcijev karbonat.
4. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 3, pri čemu je navedeni materijal koji sadrži kalcijev karbonat materijal u obliku čestica.
5. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 4, formuliran kao topikalni oblik doziranja.
6. Proizvodni proizvod koji sadrži citratnu sol i materijal koji sadrži kalcijev karbonat, proizvodni proizvod je konfiguriran za nanošenje sastava na ozlijeđenu krvnu žilu i/ili tkivo i namijenjen je za smanjenje ili zaustavljanje krvarenja kod subjektu kojem je to potrebno.
7. Proizvodni proizvod za upotrebu prema patentnom zahtjevu 6, pri čemu materijal koji sadrži kalcijev karbonat sadrži kristalni kalcijev karbonat.
8. Proizvodni proizvod za upotrebu prema patentnom zahtjevu 6, pri čemu materijal koji sadrži kalcijev karbonat sadrži amorfni kalcijev karbonat.
9. Proizvodni proizvod za upotrebu prema bilo kojem od patentnih zahtjeva 6 do 8, pri čemu je navedeni materijal koji sadrži kalcijev karbonat materijal u obliku čestica.
10. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 5, za indukciju koagulacije krvi kod navedenog subjekta.
11. Sastav za upotrebu prema patentnom zahtjevu 10, pri čemu navedeno induciranje koagulacije krvi sadrži dovođenje krvi u kontakt sa sastavom.
12. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 5, 10 i 11, pri čemu se najmanje 50 % krvi zgruša nakon kontakta sa sastavom kraćim od 10 minuta.
13. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 5 i 10 do 12, pri čemu najmanje 50 % navedene zgrušane krvi ostaje zgrušano najmanje 2 sata.
14. Sastav za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 5 i 10 do 13, pri čemu spomenuto izazivanje koagulacije krvi uključuje primjenu sastava na ozlijeđenu krvnu žilu.
15. Sastav za upotrebu prema patentnom zahtjevu 14, pri čemu je navedena krvna žila unutarnja krvna žila ili je krvna žila unutarnjeg tkiva.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562221040P | 2015-09-20 | 2015-09-20 | |
| EP16845849.5A EP3349766B1 (en) | 2015-09-20 | 2016-09-20 | Anti-hemorrhaging compositions |
| PCT/IL2016/051039 WO2017046809A1 (en) | 2015-09-20 | 2016-09-20 | Anti-hemorrhaging compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20230336T1 true HRP20230336T1 (hr) | 2023-05-26 |
Family
ID=58288224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20230336TT HRP20230336T1 (hr) | 2015-09-20 | 2016-09-20 | Sastavi protiv krvarenja |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10695364B2 (hr) |
| EP (1) | EP3349766B1 (hr) |
| ES (1) | ES2941360T3 (hr) |
| HR (1) | HRP20230336T1 (hr) |
| SI (1) | SI3349766T1 (hr) |
| WO (1) | WO2017046809A1 (hr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3349766B1 (en) | 2015-09-20 | 2023-01-11 | Ariel-University Research and Development Company Ltd. | Anti-hemorrhaging compositions |
| TWI739485B (zh) * | 2019-08-19 | 2021-09-11 | 喜樂醫療器材股份有限公司 | 止血方法 |
| IL296230A (en) | 2020-03-05 | 2022-11-01 | Ariel Scient Innovations Ltd | preparations to stop bleeding |
| CN112941143A (zh) * | 2021-01-28 | 2021-06-11 | 南京可诺医疗技术有限公司 | 一种简单便捷的检测凝血和血小板功能的试剂及其应用 |
| WO2023037368A1 (en) * | 2021-09-08 | 2023-03-16 | Ariel Scientific Innovations Ltd. | Methods of treating non-bleeding wounds, chronic wounds, inflammatory pain and nociceptive pain |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000062828A1 (en) * | 1996-04-30 | 2000-10-26 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
| FR2757770B1 (fr) * | 1996-12-30 | 1999-02-26 | Inoteb | Procede de preparation d'une colle biologique capable de coaguler par simple addition d'ions calcium |
| EP2002839A1 (en) * | 1998-04-17 | 2008-12-17 | Ortho McNeil Pharmaceutical, Inc. | Folic acid-containing pharmaceutical compositions, and related methods and delivery systems |
| JP2007191453A (ja) * | 2006-01-23 | 2007-08-02 | Gifu Prefecture | 非晶質クエン酸カルシウム・炭酸カルシウム複合体及びその製造方法 |
| AU2012330450B2 (en) * | 2011-10-27 | 2017-04-27 | Baxter Healthcare Sa | Hemostatic compositions |
| US9651567B2 (en) | 2013-05-14 | 2017-05-16 | Cgt Enterprises, Llc | Test strips for determining coagulation factor activities |
| EP3082866A4 (en) | 2013-12-16 | 2017-06-14 | The University Of British Columbia | Self-fueled particles for propulsion through flowing aqueous fluids |
| US20170027982A1 (en) | 2014-04-29 | 2017-02-02 | Ariel-University Research And Development Company Ltd. | Anticoagulant and decoagulant methods, compositions and devices |
| EP3349766B1 (en) | 2015-09-20 | 2023-01-11 | Ariel-University Research and Development Company Ltd. | Anti-hemorrhaging compositions |
-
2016
- 2016-09-20 EP EP16845849.5A patent/EP3349766B1/en active Active
- 2016-09-20 US US15/761,447 patent/US10695364B2/en active Active
- 2016-09-20 SI SI201631687T patent/SI3349766T1/sl unknown
- 2016-09-20 HR HRP20230336TT patent/HRP20230336T1/hr unknown
- 2016-09-20 ES ES16845849T patent/ES2941360T3/es active Active
- 2016-09-20 WO PCT/IL2016/051039 patent/WO2017046809A1/en active Application Filing
-
2020
- 2020-06-17 US US16/903,435 patent/US20200306291A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2941360T3 (es) | 2023-05-22 |
| EP3349766B1 (en) | 2023-01-11 |
| US10695364B2 (en) | 2020-06-30 |
| US20190076470A1 (en) | 2019-03-14 |
| US20200306291A1 (en) | 2020-10-01 |
| WO2017046809A1 (en) | 2017-03-23 |
| EP3349766A1 (en) | 2018-07-25 |
| SI3349766T1 (sl) | 2023-05-31 |
| EP3349766A4 (en) | 2019-05-01 |
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