HRP20050815A2 - 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound - Google Patents

2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound

Info

Publication number
HRP20050815A2
HRP20050815A2 HR20050815A HRP20050815A HRP20050815A2 HR P20050815 A2 HRP20050815 A2 HR P20050815A2 HR 20050815 A HR20050815 A HR 20050815A HR P20050815 A HRP20050815 A HR P20050815A HR P20050815 A2 HRP20050815 A2 HR P20050815A2
Authority
HR
Croatia
Prior art keywords
sulfonylamino
pyridin
methoxy
propyl
butyl
Prior art date
Application number
HR20050815A
Other languages
Croatian (hr)
Inventor
Brendel Joachim
Goegelein Heinz
Wirth Klaus
Gert
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of HRP20050815A2 publication Critical patent/HRP20050815A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Abstract

Izum se odnosi na 2-(butil-1-sulfonilamino)-N-[1(R)-(6-metoksi-piridin-3-il)-propil]-benzamid formule (I),i na njegove farmaceutski prihvatljive soli, njihovu proizvodnju i upotrebu, posebno za liječenje i prevenciju aritmija pretklijetke, na primjer fibrilacije pretklijetke (atrijalne fibrilacije)ili treperenja pretklijetke (atrijalnog treperenja).The invention relates to 2- (butyl-1-sulfonylamino) -N- [1 (R) - (6-methoxy-pyridin-3-yl) -propyl] -benzamide of formula (I), and to pharmaceutically acceptable salts thereof, their production and use, in particular for the treatment and prevention of atrial arrhythmias, for example atrial fibrillation (atrial fibrillation) or atrial fibrillation (atrial fibrillation).

HR20050815A 2003-03-18 2005-09-16 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound HRP20050815A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10312073A DE10312073A1 (en) 2003-03-18 2003-03-18 2- (Butyl-1-sulfonylamino) -N- [1 (R) - (6-methoxypyridin-3yl) -propyl] -benzamide, its use as a medicament and pharmaceutical compositions containing the same
PCT/EP2004/002247 WO2004083157A1 (en) 2003-03-18 2004-03-05 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound

Publications (1)

Publication Number Publication Date
HRP20050815A2 true HRP20050815A2 (en) 2006-09-30

Family

ID=32920928

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050815A HRP20050815A2 (en) 2003-03-18 2005-09-16 2-(butyl-1-sulfonylamino)-n-[1(r)-(6-methoxy-pyridin-3-yl)-propyl]-benzamid, the use thereof in the form of drug an pharmaceutical preparations containing said compound

Country Status (22)

Country Link
EP (1) EP1606237A1 (en)
JP (1) JP2006520343A (en)
KR (1) KR20050110681A (en)
CN (1) CN100361943C (en)
AR (1) AR043622A1 (en)
AU (1) AU2004222137A1 (en)
BR (1) BRPI0408441A (en)
CA (1) CA2519022A1 (en)
DE (1) DE10312073A1 (en)
HK (1) HK1086819A1 (en)
HR (1) HRP20050815A2 (en)
MA (1) MA27749A1 (en)
MX (1) MXPA05009763A (en)
MY (1) MY176510A (en)
NO (1) NO20054472L (en)
NZ (1) NZ542476A (en)
PE (1) PE20050307A1 (en)
RS (1) RS20050690A (en)
RU (1) RU2333202C2 (en)
TW (1) TW200500342A (en)
WO (1) WO2004083157A1 (en)
ZA (1) ZA200506328B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004009931A1 (en) * 2004-02-26 2005-09-15 Aventis Pharma Deutschland Gmbh Use of specific 2-substituted benzamides for treating and preventing cardiac insufficiency, especially where caused by diastolic dysfunction, act by inhibition of the Kv1.5 potassium channel
US7569589B2 (en) 2004-07-29 2009-08-04 Merck & Co., Inc. Potassium channel inhibitors
DE102005028845A1 (en) * 2005-06-22 2006-12-28 Sanofi-Aventis Deutschland Gmbh New substituted pyrrolidin-2-ones, piperidin-2-ones and isothiazolidine-1,1-dioxides useful for treating e.g. dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, breast cancer and heart failure
AU2006276292B2 (en) * 2005-07-22 2010-09-16 Merck Sharp & Dohme Corp. Potassium channel inhibitors
JP5685203B2 (en) * 2009-05-29 2015-03-18 ラクオリア創薬株式会社 Aryl-substituted carboxamide derivatives as calcium channel blockers or sodium channel blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10121003A1 (en) * 2001-04-28 2002-12-19 Aventis Pharma Gmbh Anthranilic acid amides, processes for their preparation, their use as medicaments and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
BRPI0408441A (en) 2006-04-04
RU2005132163A (en) 2006-04-10
PE20050307A1 (en) 2005-06-08
CN1756728A (en) 2006-04-05
NO20054472L (en) 2005-09-27
HK1086819A1 (en) 2006-09-29
MA27749A1 (en) 2006-02-01
CN100361943C (en) 2008-01-16
EP1606237A1 (en) 2005-12-21
RU2333202C2 (en) 2008-09-10
KR20050110681A (en) 2005-11-23
AR043622A1 (en) 2005-08-03
AU2004222137A1 (en) 2004-09-30
WO2004083157A1 (en) 2004-09-30
TW200500342A (en) 2005-01-01
ZA200506328B (en) 2006-04-26
JP2006520343A (en) 2006-09-07
MXPA05009763A (en) 2006-01-27
DE10312073A1 (en) 2004-09-30
NZ542476A (en) 2008-05-30
CA2519022A1 (en) 2004-09-30
RS20050690A (en) 2008-04-04
MY176510A (en) 2020-08-12

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