AR043622A1 - "2- (BUTIL-1 SULFONYLAMINE) - N- [1 (R) - (6 - METOXIPIRIDIN - 3 - IL - PROPIL] BENZAMIDA, ITS USE AS A MEDICINAL PRODUCT AND PHARMACEUTICAL PREPARATIONS THAT INCLUDE IT - Google Patents

"2- (BUTIL-1 SULFONYLAMINE) - N- [1 (R) - (6 - METOXIPIRIDIN - 3 - IL - PROPIL] BENZAMIDA, ITS USE AS A MEDICINAL PRODUCT AND PHARMACEUTICAL PREPARATIONS THAT INCLUDE IT

Info

Publication number
AR043622A1
AR043622A1 ARP040100866A ARP040100866A AR043622A1 AR 043622 A1 AR043622 A1 AR 043622A1 AR P040100866 A ARP040100866 A AR P040100866A AR P040100866 A ARP040100866 A AR P040100866A AR 043622 A1 AR043622 A1 AR 043622A1
Authority
AR
Argentina
Prior art keywords
metoxipiridin
benzamida
propil
butil
sulfonylamine
Prior art date
Application number
ARP040100866A
Other languages
Spanish (es)
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of AR043622A1 publication Critical patent/AR043622A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Se refiere a la 2-(butil-1-sulfonilamino)-N-[1(R)-(6-metoxipiridin-3-il)propil]-benzamida de fórmula (1), y a sus sales farmacéuticamente aceptables, a su preparación y uso, en particular para el tratamiento y profilaxis de arritmias auriculares, por ejemplo fibrilación auricular o aleteos auriculares.It refers to 2- (butyl-1-sulfonylamino) -N- [1 (R) - (6-methoxypyridin-3-yl) propyl] -benzamide of formula (1), and its pharmaceutically acceptable salts, to its preparation and use, in particular for the treatment and prophylaxis of atrial arrhythmias, for example atrial fibrillation or atrial flutters.

ARP040100866A 2003-03-18 2004-03-16 "2- (BUTIL-1 SULFONYLAMINE) - N- [1 (R) - (6 - METOXIPIRIDIN - 3 - IL - PROPIL] BENZAMIDA, ITS USE AS A MEDICINAL PRODUCT AND PHARMACEUTICAL PREPARATIONS THAT INCLUDE IT AR043622A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10312073A DE10312073A1 (en) 2003-03-18 2003-03-18 2- (Butyl-1-sulfonylamino) -N- [1 (R) - (6-methoxypyridin-3yl) -propyl] -benzamide, its use as a medicament and pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
AR043622A1 true AR043622A1 (en) 2005-08-03

Family

ID=32920928

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040100866A AR043622A1 (en) 2003-03-18 2004-03-16 "2- (BUTIL-1 SULFONYLAMINE) - N- [1 (R) - (6 - METOXIPIRIDIN - 3 - IL - PROPIL] BENZAMIDA, ITS USE AS A MEDICINAL PRODUCT AND PHARMACEUTICAL PREPARATIONS THAT INCLUDE IT

Country Status (22)

Country Link
EP (1) EP1606237A1 (en)
JP (1) JP2006520343A (en)
KR (1) KR20050110681A (en)
CN (1) CN100361943C (en)
AR (1) AR043622A1 (en)
AU (1) AU2004222137A1 (en)
BR (1) BRPI0408441A (en)
CA (1) CA2519022A1 (en)
DE (1) DE10312073A1 (en)
HK (1) HK1086819A1 (en)
HR (1) HRP20050815A2 (en)
MA (1) MA27749A1 (en)
MX (1) MXPA05009763A (en)
MY (1) MY176510A (en)
NO (1) NO20054472L (en)
NZ (1) NZ542476A (en)
PE (1) PE20050307A1 (en)
RS (1) RS20050690A (en)
RU (1) RU2333202C2 (en)
TW (1) TW200500342A (en)
WO (1) WO2004083157A1 (en)
ZA (1) ZA200506328B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004009931A1 (en) * 2004-02-26 2005-09-15 Aventis Pharma Deutschland Gmbh Use of specific 2-substituted benzamides for treating and preventing cardiac insufficiency, especially where caused by diastolic dysfunction, act by inhibition of the Kv1.5 potassium channel
US7569589B2 (en) 2004-07-29 2009-08-04 Merck & Co., Inc. Potassium channel inhibitors
DE102005028845A1 (en) * 2005-06-22 2006-12-28 Sanofi-Aventis Deutschland Gmbh New substituted pyrrolidin-2-ones, piperidin-2-ones and isothiazolidine-1,1-dioxides useful for treating e.g. dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, breast cancer and heart failure
CA2615440A1 (en) * 2005-07-22 2007-02-08 Merck & Co., Inc. Potassium channel inhibitors
EP3632899A1 (en) * 2009-05-29 2020-04-08 RaQualia Pharma Inc. Aryl substituted carboxamide derivatives as calcium or sodium channel blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10121003A1 (en) * 2001-04-28 2002-12-19 Aventis Pharma Gmbh Anthranilic acid amides, processes for their preparation, their use as medicaments and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
CN1756728A (en) 2006-04-05
ZA200506328B (en) 2006-04-26
JP2006520343A (en) 2006-09-07
EP1606237A1 (en) 2005-12-21
CA2519022A1 (en) 2004-09-30
CN100361943C (en) 2008-01-16
NZ542476A (en) 2008-05-30
HK1086819A1 (en) 2006-09-29
MXPA05009763A (en) 2006-01-27
BRPI0408441A (en) 2006-04-04
HRP20050815A2 (en) 2006-09-30
NO20054472L (en) 2005-09-27
RU2005132163A (en) 2006-04-10
MY176510A (en) 2020-08-12
KR20050110681A (en) 2005-11-23
PE20050307A1 (en) 2005-06-08
RU2333202C2 (en) 2008-09-10
AU2004222137A1 (en) 2004-09-30
MA27749A1 (en) 2006-02-01
DE10312073A1 (en) 2004-09-30
TW200500342A (en) 2005-01-01
WO2004083157A1 (en) 2004-09-30
RS20050690A (en) 2008-04-04

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