HRP20040742B1 - Stable salts of o-acetylsalicylic acid containing basic amino acids ii - Google Patents

Stable salts of o-acetylsalicylic acid containing basic amino acids ii

Info

Publication number: HRP20040742B1
Authority: HR; Croatia
Prior art keywords: basic amino; acetylsalicylic acid; amino acids; acid containing; containing basic
Prior art date: 2002-01-18

Application number

HR20040742A

Other languages

English (en)

Croatian (hr)

Inventor

Ecker Felix

B�llesbach Ralf

Ledwoch Wolfram

Franckowiak Gerhard

Gessner Uwe

Petersen-Braun Marianne

Original Assignee

Bayer Healthcare Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-18

Filing date

2004-08-17

Publication date

2008-05-31

2004-08-17 Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag

2005-08-31 Publication of HRP20040742A2 publication Critical patent/HRP20040742A2/hr

2008-05-31 Publication of HRP20040742B1 publication Critical patent/HRP20040742B1/xx

Links

150000001413 amino acids Chemical class 0.000 title abstract 2
BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical class CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
239000002245 particle Substances 0.000 abstract 3
229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
UQJRAOCVSMOMNW-UHFFFAOYSA-N acetyl 2-hydroxybenzoate Chemical class CC(=O)OC(=O)C1=CC=CC=C1O UQJRAOCVSMOMNW-UHFFFAOYSA-N 0.000 abstract 1
238000007908 dry granulation Methods 0.000 abstract 1
235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
239000008108 microcrystalline cellulose Substances 0.000 abstract 1
229940016286 microcrystalline cellulose Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Rheumatology (AREA)
Biophysics (AREA)
Physiology (AREA)
Hospice & Palliative Care (AREA)
Nutrition Science (AREA)
Zoology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hematology (AREA)

HR20040742A 2002-01-18 2004-08-17 Stable salts of o-acetylsalicylic acid containing basic amino acids ii HRP20040742B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10202019A DE10202019A1 (de)	2002-01-18	2002-01-18	Stabile Salze von o-Acetylsalicylsäure mit basischen Aminosäuren II
PCT/EP2003/000059 WO2003059323A2 (fr)	2002-01-18	2003-01-07	Sels stables d'acide o-acetylsalicylique contenant des acides amines ii basiques

Publications (2)

Publication Number	Publication Date
HRP20040742A2 HRP20040742A2 (en)	2005-08-31
HRP20040742B1 true HRP20040742B1 (en)	2008-05-31

Family

ID=7712593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20040742A HRP20040742B1 (en)	2002-01-18	2004-08-17	Stable salts of o-acetylsalicylic acid containing basic amino acids ii

Country Status (31)

Country	Link
US (1)	US20050171070A1 (fr)
EP (1)	EP1469835B1 (fr)
JP (1)	JP2005519892A (fr)
KR (1)	KR20040079936A (fr)
CN (1)	CN1298314C (fr)
AR (1)	AR038298A1 (fr)
AT (1)	ATE378040T1 (fr)
AU (1)	AU2003235700B2 (fr)
BR (1)	BR0307009A (fr)
CA (1)	CA2473893A1 (fr)
CO (1)	CO5611102A2 (fr)
CU (1)	CU20040161A7 (fr)
DE (2)	DE10202019A1 (fr)
EC (1)	ECSP045192A (fr)
ES (1)	ES2297166T3 (fr)
GT (1)	GT200300004A (fr)
HK (1)	HK1080371A1 (fr)
HN (1)	HN2003000015A (fr)
HR (1)	HRP20040742B1 (fr)
IL (1)	IL162881A0 (fr)
MX (1)	MXPA04006832A (fr)
NO (1)	NO20043404L (fr)
NZ (1)	NZ534128A (fr)
PE (1)	PE20030731A1 (fr)
PL (1)	PL370197A1 (fr)
RS (1)	RS63804A (fr)
SV (1)	SV2004001457A (fr)
TW (1)	TWI265810B (fr)
UY (1)	UY27612A1 (fr)
WO (1)	WO2003059323A2 (fr)
ZA (1)	ZA200405533B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102004025535A1 (de) *	2004-05-25	2005-12-22	Bayer Healthcare Ag	Kombination von Salzen der o-Acetylsalicylsäure und Alpha-Glucosidase-Inhibitoren
DE102005025283A1 (de) *	2005-06-02	2006-12-07	Bayer Healthcare Ag	Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin
DE102005049293A1 (de) *	2005-10-15	2007-04-26	Bayer Healthcare Ag	Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
DE102008004386A1 (de)	2008-01-14	2009-07-23	Activaero Gmbh	Verwendung eines Acetylsalicylsäuresalzes zur Behandlung viraler Infektionen
JP5309977B2 (ja) *	2008-12-26	2013-10-09	ライオン株式会社	チュアブル錠
US8173625B2 (en)	2009-05-08	2012-05-08	Theaprin Pharmaceuticals Inc.	Intravenous formulation with water-soluble cocrystals of acetylsalicylic acid and theanine
CN102803199B (zh) *	2009-06-25	2015-04-15	泰特拉有限公司	乙酰水杨酸盐
JP5563835B2 (ja) *	2010-01-15	2014-07-30	全星薬品工業株式会社	アスピリン錠剤の製造方法
ITMI20121144A1 (it) *	2012-06-28	2013-12-29	Dipharma Francis Srl	Procedimento per la preparazione di un sale di un farmaco antinfiammatorio non steroideo
JP7012725B2 (ja) *	2016-12-23	2022-01-28	アスピエアーゲーエムベーハー	アセチルサリチル酸リジン・グリシン粒子の改良された合成
RU2738831C1 (ru) *	2020-03-03	2020-12-17	федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России)	Способ консервативного лечения невралгии тройничного нерва

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4265888A (en) *	1979-07-06	1981-05-05	The Green Cross Corporation	Acetylsalicylate powder preparation for injection
US4988683A (en) *	1987-03-04	1991-01-29	Jerome Corbiere	New pharmaceutical compositions for the buccal tract and process for their preparation
WO2002005782A2 (fr) *	2000-07-18	2002-01-24	Bayer Aktiengesellschaft	Sels stables d'acide o-acetylsalicylique avec des acides amines basiques

2002
- 2002-01-18 DE DE10202019A patent/DE10202019A1/de not_active Withdrawn
2003
- 2003-01-07 DE DE50308596T patent/DE50308596D1/de not_active Expired - Lifetime
- 2003-01-07 CN CNB038064154A patent/CN1298314C/zh not_active Expired - Fee Related
- 2003-01-07 ES ES03729426T patent/ES2297166T3/es not_active Expired - Lifetime
- 2003-01-07 PL PL03370197A patent/PL370197A1/xx not_active Application Discontinuation
- 2003-01-07 BR BR0307009-3A patent/BR0307009A/pt not_active IP Right Cessation
- 2003-01-07 NZ NZ534128A patent/NZ534128A/en not_active IP Right Cessation
- 2003-01-07 WO PCT/EP2003/000059 patent/WO2003059323A2/fr active IP Right Grant
- 2003-01-07 MX MXPA04006832A patent/MXPA04006832A/es active IP Right Grant
- 2003-01-07 AU AU2003235700A patent/AU2003235700B2/en not_active Ceased
- 2003-01-07 AT AT03729426T patent/ATE378040T1/de not_active IP Right Cessation
- 2003-01-07 IL IL16288103A patent/IL162881A0/xx unknown
- 2003-01-07 RS YU63804A patent/RS63804A/sr unknown
- 2003-01-07 KR KR10-2004-7011078A patent/KR20040079936A/ko not_active Application Discontinuation
- 2003-01-07 CA CA002473893A patent/CA2473893A1/fr not_active Abandoned
- 2003-01-07 JP JP2003559486A patent/JP2005519892A/ja active Pending
- 2003-01-07 EP EP03729426A patent/EP1469835B1/fr not_active Expired - Lifetime
- 2003-01-07 US US10/501,677 patent/US20050171070A1/en not_active Abandoned
- 2003-01-14 GT GT200300004A patent/GT200300004A/es unknown
- 2003-01-15 UY UY27612A patent/UY27612A1/es not_active Application Discontinuation
- 2003-01-16 AR ARP030100121A patent/AR038298A1/es not_active Application Discontinuation
- 2003-01-17 TW TW092100932A patent/TWI265810B/zh not_active IP Right Cessation
- 2003-01-17 HN HN2003000015A patent/HN2003000015A/es unknown
- 2003-01-17 SV SV2003001457A patent/SV2004001457A/es unknown
- 2003-01-17 PE PE2003000052A patent/PE20030731A1/es not_active Application Discontinuation
2004
- 2004-07-13 ZA ZA200405533A patent/ZA200405533B/en unknown
- 2004-07-15 EC EC2004005192A patent/ECSP045192A/es unknown
- 2004-07-19 CU CU20040161A patent/CU20040161A7/es unknown
- 2004-08-16 NO NO20043404A patent/NO20043404L/no not_active Application Discontinuation
- 2004-08-17 CO CO04079945A patent/CO5611102A2/es not_active Application Discontinuation
- 2004-08-17 HR HR20040742A patent/HRP20040742B1/xx not_active IP Right Cessation
2006
- 2006-01-06 HK HK06100280A patent/HK1080371A1/xx not_active IP Right Cessation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4265888A (en) *	1979-07-06	1981-05-05	The Green Cross Corporation	Acetylsalicylate powder preparation for injection
US4988683A (en) *	1987-03-04	1991-01-29	Jerome Corbiere	New pharmaceutical compositions for the buccal tract and process for their preparation
WO2002005782A2 (fr) *	2000-07-18	2002-01-24	Bayer Aktiengesellschaft	Sels stables d'acide o-acetylsalicylique avec des acides amines basiques

Also Published As

Publication number	Publication date
BR0307009A (pt)	2004-11-03
JP2005519892A (ja)	2005-07-07
CA2473893A1 (fr)	2003-07-24
NZ534128A (en)	2005-08-26
KR20040079936A (ko)	2004-09-16
ES2297166T3 (es)	2008-05-01
IL162881A0 (en)	2005-11-20
WO2003059323A2 (fr)	2003-07-24
CU20040161A7 (es)	2007-03-23
HN2003000015A (es)	2003-08-22
NO20043404L (no)	2004-08-16
DE10202019A1 (de)	2003-07-24
PE20030731A1 (es)	2003-09-22
EP1469835A2 (fr)	2004-10-27
AR038298A1 (es)	2005-01-12
DE50308596D1 (de)	2007-12-27
AU2003235700A1 (en)	2003-07-30
AU2003235700B2 (en)	2007-06-28
CN1642528A (zh)	2005-07-20
TW200306199A (en)	2003-11-16
PL370197A1 (en)	2005-05-16
HRP20040742A2 (en)	2005-08-31
TWI265810B (en)	2006-11-11
GT200300004A (es)	2003-08-22
UY27612A1 (es)	2003-08-29
RS63804A (en)	2006-12-15
SV2004001457A (es)	2004-05-07
ZA200405533B (en)	2005-07-13
EP1469835B1 (fr)	2007-11-14
MXPA04006832A (es)	2004-12-06
US20050171070A1 (en)	2005-08-04
ATE378040T1 (de)	2007-11-15
WO2003059323A3 (fr)	2004-03-11
ECSP045192A (es)	2004-08-27
CN1298314C (zh)	2007-02-07
CO5611102A2 (es)	2006-02-28
HK1080371A1 (en)	2006-04-28

Legal Events

Date	Code	Title	Description
2005-08-31	A1OB	Publication of a patent application
2006-02-14	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2008-05-31	B1PR	Patent granted
2009-12-31	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20091231 Year of fee payment: 8
2010-04-21	PPPP	Transfer of rights	Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE
2011-07-08	PBON	Lapse due to non-payment of renewal fee	Effective date: 20110108

Publication	Publication Date	Title
RS50329B (sr)	2009-09-08	Stabilne soli o-acetilsalicilne kiseline sa baznim amino-kiselinama
HRP20040742B1 (en)	2008-05-31	Stable salts of o-acetylsalicylic acid containing basic amino acids ii
JP2668880B2 (ja)	1997-10-27	被覆アミノ酸類の製造方法
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HRP20150037T4 (hr)	2022-09-02	Farmaceutske formulacije koje sadrže metilnaltrekson
HRP20221195T1 (hr)	2022-12-09	Spojevi koji ciljaju psma i njihova uporaba
AR048986A1 (es)	2006-06-14	Particulas encapsuladas
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