HK69992A - Manufacture of tetra-alkyl ethenylidene bis phosphonates and use thereof in pharmaceutical compositions - Google Patents

Manufacture of tetra-alkyl ethenylidene bis phosphonates and use thereof in pharmaceutical compositions

Info

Publication number: HK69992A
Authority: HK; Hong Kong
Prior art keywords: tetra; manufacture; pharmaceutical compositions; alkyl; phosphonates
Prior art date: 1985-11-04

Application number

HK699/92A

Other languages

English (en)

Inventor

Charles Raymond Degenhardt

Duane Larry Charbonneau

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-04

Filing date

1992-09-17

Publication date

1992-09-25

1992-09-17 Application filed by Procter & Gamble filed Critical Procter & Gamble

1992-09-25 Publication of HK69992A publication Critical patent/HK69992A/xx

Links

229940122361 Bisphosphonate Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4025—Esters of poly(thio)phosphonic acids
- C07F9/4028—Esters of poly(thio)phosphonic acids containing no further substituents than -PO3H2 groups in free or esterified form
- C07F9/4031—Acyclic unsaturated derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Detergent Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

HK699/92A 1985-11-04 1992-09-17 Manufacture of tetra-alkyl ethenylidene bis phosphonates and use thereof in pharmaceutical compositions HK69992A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US79530685A	1985-11-04	1985-11-04
US06/855,877 US4820698A (en)	1985-11-04	1986-04-23	Antimicrobial agents and process for their manufacture

Publications (1)

Publication Number	Publication Date
HK69992A true HK69992A (en)	1992-09-25

Family

ID=27121606

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK699/92A HK69992A (en)	1985-11-04	1992-09-17	Manufacture of tetra-alkyl ethenylidene bis phosphonates and use thereof in pharmaceutical compositions

Country Status (16)

Country	Link
US (1)	US4820698A (da)
EP (1)	EP0221611A3 (da)
JP (2)	JP2525379B2 (da)
KR (1)	KR950005876B1 (da)
AU (1)	AU607685B2 (da)
CA (1)	CA1291765C (da)
DK (1)	DK167809B1 (da)
EG (1)	EG18789A (da)
FI (1)	FI864462A (da)
GB (1)	GB2183652B (da)
HK (1)	HK69992A (da)
IL (1)	IL80480A (da)
NO (1)	NO864378L (da)
NZ (1)	NZ218149A (da)
PH (1)	PH24524A (da)
SG (1)	SG76092G (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5089266A (en) *	1989-10-10	1992-02-18	Merlin Lee	Non-toxic insecticide composition and method for killing specific insects
FI92465C (fi) *	1993-04-14	1994-11-25	Risto Tapani Lehtinen	Menetelmä endo-osteaalisten materiaalien käsittelemiseksi
US5854227A (en) *	1994-03-04	1998-12-29	Hartmann; John F.	Therapeutic derivatives of diphosphonates
DE19615812A1 (de) *	1996-04-20	1997-10-23	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
US6210695B1 (en)	1997-06-04	2001-04-03	The Procter & Gamble Company	Leave-on antimicrobial compositions
US5968539A (en) *	1997-06-04	1999-10-19	Procter & Gamble Company	Mild, rinse-off antimicrobial liquid cleansing compositions which provide residual benefit versus gram negative bacteria
US6287577B1 (en)	1997-11-12	2001-09-11	The Procter & Gamble Company	Leave-on antimicrobial compositions which provide improved residual benefit versus gram positive bacteria
US6190675B1 (en)	1997-06-04	2001-02-20	Procter & Gamble Company	Mild, rinse-off antimicrobial liquid cleansing compositions which provide improved residual benefit versus gram positive bacteria
US6214363B1 (en)	1997-11-12	2001-04-10	The Procter & Gamble Company	Liquid antimicrobial cleansing compositions which provide residual benefit versus gram negative bacteria
US6197315B1 (en)	1997-06-04	2001-03-06	Procter & Gamble Company	Antimicrobial wipes which provide improved residual benefit versus gram negative bacteria
US6183763B1 (en)	1997-06-04	2001-02-06	Procter & Gamble Company	Antimicrobial wipes which provide improved immediate germ reduction
US6190674B1 (en)	1997-06-04	2001-02-20	Procter & Gamble Company	Liquid antimicrobial cleansing compositions
US6284259B1 (en)	1997-11-12	2001-09-04	The Procter & Gamble Company	Antimicrobial wipes which provide improved residual benefit versus Gram positive bacteria
US6183757B1 (en)	1997-06-04	2001-02-06	Procter & Gamble Company	Mild, rinse-off antimicrobial cleansing compositions which provide improved immediate germ reduction during washing
US6099853A (en) *	1997-09-04	2000-08-08	Protein Express	Vaginal suppository vaccine for urogenital infections
US7135191B2 (en) *	1997-09-04	2006-11-14	Zsolt Istvan Hertelendy	Urogenital or anorectal transmucosal vaccine delivery system
US6287583B1 (en)	1997-11-12	2001-09-11	The Procter & Gamble Company	Low-pH, acid-containing personal care compositions which exhibit reduced sting
AU754862B2 (en)	1998-12-23	2002-11-28	Bioagency Ag	Use of bisphosphonates for the prevention and treatment of infectious processes
DE19902924A1 (de) *	1999-01-26	2000-08-03	Hassan Jomaa	Verwendung von phosphororganischen Verbindungen zur prophylaktischen und therapeutischen Behandlung von Infektionen
EP1956903B1 (en) *	2005-11-29	2017-01-11	Ambria Dermatology AB	Use of an absorption product comprising pentane-1, 5-diol as deodorant
US20090111736A1 (en) *	2007-10-29	2009-04-30	Sri International	Orally-Absorbed Solid Dose Formulation for Vancomycin
US8222192B2 (en) *	2009-06-19	2012-07-17	R&W Medical LLC	Alcohol-based skin cleanser
EP2750711A2 (en) *	2011-08-31	2014-07-09	Mallinckrodt LLC	Remote assembly of targeted nanoparticles using h-phosphonate-ene/-yne hydrophosphonylation reactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3062792A (en) *	1960-03-01	1962-11-06	Eastman Kodak Co	Polymers derived from tetraalkyl vinylidenediphosphonates
DE1225818B (de) *	1964-03-18	1966-09-29	Monsanto Co	Verwendung wasserloeslicher Polyphosphonsaeure-verbindungen als Potenzierungsmittel fuer Bakterizide
US3544509A (en) *	1967-05-08	1970-12-01	Monsanto Co	Diphosphonic acids and salts thereof as flame retardants
GB1204967A (en) *	1967-05-08	1970-09-09	Monsanto Co	Organic phosphorus compounds, their production and use
US3576793A (en) *	1967-05-08	1971-04-27	Monsanto Co	Polymers of alkylene diphosphonic acids and salts and copolymers thereof
US3657282A (en)	1969-01-23	1972-04-18	Merck & Co Inc	Carboxyepoxyethyl-1-phosphonic acid and derivatives

1986
- 1986-04-23 US US06/855,877 patent/US4820698A/en not_active Expired - Lifetime
- 1986-10-28 EP EP86201890A patent/EP0221611A3/en not_active Withdrawn
- 1986-10-30 PH PH34431A patent/PH24524A/en unknown
- 1986-11-03 NZ NZ218149A patent/NZ218149A/xx unknown
- 1986-11-03 CA CA000522069A patent/CA1291765C/en not_active Expired - Fee Related
- 1986-11-03 GB GB8626240A patent/GB2183652B/en not_active Expired
- 1986-11-03 AU AU64679/86A patent/AU607685B2/en not_active Ceased
- 1986-11-03 FI FI864462A patent/FI864462A/fi not_active Application Discontinuation
- 1986-11-03 NO NO864378A patent/NO864378L/no unknown
- 1986-11-03 IL IL80480A patent/IL80480A/xx unknown
- 1986-11-04 JP JP61262597A patent/JP2525379B2/ja not_active Expired - Lifetime
- 1986-11-04 DK DK526586A patent/DK167809B1/da not_active IP Right Cessation
- 1986-11-04 KR KR1019860009273A patent/KR950005876B1/ko not_active IP Right Cessation
- 1986-11-04 EG EG68486A patent/EG18789A/xx active
1992
- 1992-07-28 SG SG760/92A patent/SG76092G/en unknown
- 1992-09-17 HK HK699/92A patent/HK69992A/xx not_active IP Right Cessation
1995
- 1995-08-30 JP JP7221730A patent/JP2541794B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK167809B1 (da)	1993-12-20
EG18789A (en)	1995-07-27
NO864378D0 (no)	1986-11-03
EP0221611A3 (en)	1988-01-27
GB2183652B (en)	1989-10-18
CA1291765C (en)	1991-11-05
JPH08104634A (ja)	1996-04-23
DK526586D0 (da)	1986-11-04
FI864462A (fi)	1987-05-05
IL80480A (en)	1991-12-12
IL80480A0 (en)	1987-02-27
US4820698A (en)	1989-04-11
FI864462A0 (fi)	1986-11-03
NO864378L (no)	1987-05-05
NZ218149A (en)	1990-03-27
KR870004997A (ko)	1987-06-04
EP0221611A2 (en)	1987-05-13
JPS62167790A (ja)	1987-07-24
AU6467986A (en)	1987-05-07
DK526586A (da)	1987-05-05
JP2541794B2 (ja)	1996-10-09
PH24524A (en)	1990-07-18
GB2183652A (en)	1987-06-10
AU607685B2 (en)	1991-03-14
JP2525379B2 (ja)	1996-08-21
KR950005876B1 (ko)	1995-06-02
SG76092G (en)	1992-10-02
GB8626240D0 (en)	1986-12-03

Legal Events

Date	Code	Title	Description
2004-06-04	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20031103
2004-12-15	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Publication	Publication Date	Title
HK69992A (en)	1992-09-25	Manufacture of tetra-alkyl ethenylidene bis phosphonates and use thereof in pharmaceutical compositions
GR861825B (en)	1986-11-18	Complexes of flavanolignanes with phospholipids preparation thereof and associated pharmaceutical compositions
IL74758A0 (en)	1985-06-30	Acyltripeptides and pharmaceutical compositions containing them
GR861601B (en)	1986-10-20	Thiazoles their production and pharmaceutical compositions containing them
NZ211145A (en)	1988-10-28	4-aza-5-alpha-androst-1-en-3-ones and pharmaceutical compositions
NZ216918A (en)	1988-11-29	Pyridazines and pharmaceutical compositions
NZ216793A (en)	1990-05-28	Phenethanolaminotetraline derivatives and pharmaceutical compositions
IL82221A0 (en)	1987-10-30	Phenyl-piperazines and pharmaceutical compositions containing them
NZ212005A (en)	1989-07-27	Pyrrolobenzimidazoles and pharmaceutical compositions
IL88433A0 (en)	1989-06-30	Diarylstyrylquinoline diacids and pharmaceutical compositions containing them
IL78980A0 (en)	1986-09-30	Nasal pharmaceutical compositions and their production
NZ218749A (en)	1990-06-26	5 to 8-membered azacyclic derivatives and pharmaceutical compositions
IL79376A (en)	1991-05-12	Substituted di-t-butylphenols and pharmaceutical compositions containing them
IL82146A0 (en)	1987-10-30	Liposomes based on phosphatidyl-inositolmannosides and pharmaceutical compositions containing them
IL79525A (en)	1990-06-10	Phenylpiperazine phosphonates and pharmaceutical compositions containing them
NZ214821A (en)	1989-03-29	Spiro-dioxolanes, -dithiolanes and -oxothiolanes and pharmaceutical compositions
NZ217798A (en)	1989-10-27	N-substituted diphenylpiperidines and pharmaceutical compositions
NZ217078A (en)	1989-01-27	N-piperidyl-benzamide derivatives and pharmaceutical compositions
NZ212953A (en)	1990-02-26	3-acyl-1-aminoalkyl-1h-indoles and pharmaceutical compositions thereof
NZ215070A (en)	1988-08-30	Imidazole-indoles and pharmaceutical compositions
NZ216720A (en)	1990-09-26	Diazinylpiperidine derivatives and pharmaceutical compositions
NZ216546A (en)	1990-03-27	Glycerol derivatives and pharmaceutical compositions
IL79003A0 (en)	1986-09-30	Tetrahydroimidazoquinazolinones and pharmaceutical compositions containing them
NZ216438A (en)	1989-01-06	Steroid-pyrazoles and pharmaceutical compositions
IL78642A0 (en)	1986-08-31	Dihydropyridines and pharmaceutical compositions containing them