IL80480A - Preparation of tetraalkyl bisphosphonates and pharmaceutical compositions containing them - Google Patents

Preparation of tetraalkyl bisphosphonates and pharmaceutical compositions containing them

Info

Publication number
IL80480A
IL80480A IL80480A IL8048086A IL80480A IL 80480 A IL80480 A IL 80480A IL 80480 A IL80480 A IL 80480A IL 8048086 A IL8048086 A IL 8048086A IL 80480 A IL80480 A IL 80480A
Authority
IL
Israel
Prior art keywords
bisphosphonates
tetraalkyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL80480A
Other languages
English (en)
Other versions
IL80480A0 (en
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of IL80480A0 publication Critical patent/IL80480A0/xx
Publication of IL80480A publication Critical patent/IL80480A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025Esters of poly(thio)phosphonic acids
    • C07F9/4028Esters of poly(thio)phosphonic acids containing no further substituents than -PO3H2 groups in free or esterified form
    • C07F9/4031Acyclic unsaturated derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL80480A 1985-11-04 1986-11-03 Preparation of tetraalkyl bisphosphonates and pharmaceutical compositions containing them IL80480A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79530685A 1985-11-04 1985-11-04
US06/855,877 US4820698A (en) 1985-11-04 1986-04-23 Antimicrobial agents and process for their manufacture

Publications (2)

Publication Number Publication Date
IL80480A0 IL80480A0 (en) 1987-02-27
IL80480A true IL80480A (en) 1991-12-12

Family

ID=27121606

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80480A IL80480A (en) 1985-11-04 1986-11-03 Preparation of tetraalkyl bisphosphonates and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4820698A (xx)
EP (1) EP0221611A3 (xx)
JP (2) JP2525379B2 (xx)
KR (1) KR950005876B1 (xx)
AU (1) AU607685B2 (xx)
CA (1) CA1291765C (xx)
DK (1) DK167809B1 (xx)
EG (1) EG18789A (xx)
FI (1) FI864462A (xx)
GB (1) GB2183652B (xx)
HK (1) HK69992A (xx)
IL (1) IL80480A (xx)
NO (1) NO864378L (xx)
NZ (1) NZ218149A (xx)
PH (1) PH24524A (xx)
SG (1) SG76092G (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089266A (en) * 1989-10-10 1992-02-18 Merlin Lee Non-toxic insecticide composition and method for killing specific insects
FI92465C (fi) * 1993-04-14 1994-11-25 Risto Tapani Lehtinen Menetelmä endo-osteaalisten materiaalien käsittelemiseksi
US5854227A (en) * 1994-03-04 1998-12-29 Hartmann; John F. Therapeutic derivatives of diphosphonates
DE19615812A1 (de) * 1996-04-20 1997-10-23 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
US6210695B1 (en) 1997-06-04 2001-04-03 The Procter & Gamble Company Leave-on antimicrobial compositions
US5968539A (en) * 1997-06-04 1999-10-19 Procter & Gamble Company Mild, rinse-off antimicrobial liquid cleansing compositions which provide residual benefit versus gram negative bacteria
US6287577B1 (en) 1997-11-12 2001-09-11 The Procter & Gamble Company Leave-on antimicrobial compositions which provide improved residual benefit versus gram positive bacteria
US6190675B1 (en) 1997-06-04 2001-02-20 Procter & Gamble Company Mild, rinse-off antimicrobial liquid cleansing compositions which provide improved residual benefit versus gram positive bacteria
US6214363B1 (en) 1997-11-12 2001-04-10 The Procter & Gamble Company Liquid antimicrobial cleansing compositions which provide residual benefit versus gram negative bacteria
US6197315B1 (en) 1997-06-04 2001-03-06 Procter & Gamble Company Antimicrobial wipes which provide improved residual benefit versus gram negative bacteria
US6183763B1 (en) 1997-06-04 2001-02-06 Procter & Gamble Company Antimicrobial wipes which provide improved immediate germ reduction
US6190674B1 (en) 1997-06-04 2001-02-20 Procter & Gamble Company Liquid antimicrobial cleansing compositions
US6284259B1 (en) 1997-11-12 2001-09-04 The Procter & Gamble Company Antimicrobial wipes which provide improved residual benefit versus Gram positive bacteria
US6183757B1 (en) 1997-06-04 2001-02-06 Procter & Gamble Company Mild, rinse-off antimicrobial cleansing compositions which provide improved immediate germ reduction during washing
US6099853A (en) * 1997-09-04 2000-08-08 Protein Express Vaginal suppository vaccine for urogenital infections
US7135191B2 (en) * 1997-09-04 2006-11-14 Zsolt Istvan Hertelendy Urogenital or anorectal transmucosal vaccine delivery system
US6287583B1 (en) 1997-11-12 2001-09-11 The Procter & Gamble Company Low-pH, acid-containing personal care compositions which exhibit reduced sting
AU754862B2 (en) 1998-12-23 2002-11-28 Bioagency Ag Use of bisphosphonates for the prevention and treatment of infectious processes
DE19902924A1 (de) * 1999-01-26 2000-08-03 Hassan Jomaa Verwendung von phosphororganischen Verbindungen zur prophylaktischen und therapeutischen Behandlung von Infektionen
EP1956903B1 (en) * 2005-11-29 2017-01-11 Ambria Dermatology AB Use of an absorption product comprising pentane-1, 5-diol as deodorant
US20090111736A1 (en) * 2007-10-29 2009-04-30 Sri International Orally-Absorbed Solid Dose Formulation for Vancomycin
US8222192B2 (en) * 2009-06-19 2012-07-17 R&W Medical LLC Alcohol-based skin cleanser
EP2750711A2 (en) * 2011-08-31 2014-07-09 Mallinckrodt LLC Remote assembly of targeted nanoparticles using h-phosphonate-ene/-yne hydrophosphonylation reactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3062792A (en) * 1960-03-01 1962-11-06 Eastman Kodak Co Polymers derived from tetraalkyl vinylidenediphosphonates
DE1225818B (de) * 1964-03-18 1966-09-29 Monsanto Co Verwendung wasserloeslicher Polyphosphonsaeure-verbindungen als Potenzierungsmittel fuer Bakterizide
US3544509A (en) * 1967-05-08 1970-12-01 Monsanto Co Diphosphonic acids and salts thereof as flame retardants
GB1204967A (en) * 1967-05-08 1970-09-09 Monsanto Co Organic phosphorus compounds, their production and use
US3576793A (en) * 1967-05-08 1971-04-27 Monsanto Co Polymers of alkylene diphosphonic acids and salts and copolymers thereof
US3657282A (en) 1969-01-23 1972-04-18 Merck & Co Inc Carboxyepoxyethyl-1-phosphonic acid and derivatives

Also Published As

Publication number Publication date
DK167809B1 (da) 1993-12-20
HK69992A (en) 1992-09-25
EG18789A (en) 1995-07-27
NO864378D0 (no) 1986-11-03
EP0221611A3 (en) 1988-01-27
GB2183652B (en) 1989-10-18
CA1291765C (en) 1991-11-05
JPH08104634A (ja) 1996-04-23
DK526586D0 (da) 1986-11-04
FI864462A (fi) 1987-05-05
IL80480A0 (en) 1987-02-27
US4820698A (en) 1989-04-11
FI864462A0 (fi) 1986-11-03
NO864378L (no) 1987-05-05
NZ218149A (en) 1990-03-27
KR870004997A (ko) 1987-06-04
EP0221611A2 (en) 1987-05-13
JPS62167790A (ja) 1987-07-24
AU6467986A (en) 1987-05-07
DK526586A (da) 1987-05-05
JP2541794B2 (ja) 1996-10-09
PH24524A (en) 1990-07-18
GB2183652A (en) 1987-06-10
AU607685B2 (en) 1991-03-14
JP2525379B2 (ja) 1996-08-21
KR950005876B1 (ko) 1995-06-02
SG76092G (en) 1992-10-02
GB8626240D0 (en) 1986-12-03

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed