US4126680A
(en)
*
|
1977-04-27 |
1978-11-21 |
Pfizer Inc. |
Tetracycline antibiotic compositions
|
DE2963584D1
(en)
*
|
1978-08-01 |
1982-10-21 |
Ciba Geigy Ag |
Stable, liquid pharmaceutical formulation, its preparation and use
|
EP0012496B1
(en)
*
|
1978-12-08 |
1983-07-20 |
Beecham Group Plc |
A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof
|
US4259331A
(en)
*
|
1979-04-16 |
1981-03-31 |
Pfizer Inc. |
Oxytetracycline compositions
|
DE3064250D1
(en)
*
|
1979-07-02 |
1983-08-25 |
Pfizer |
Long acting sulfonamide injectable compositions
|
DE3063763D1
(en)
*
|
1979-07-05 |
1983-07-21 |
Pfizer |
Sulfonamide solutions
|
US4303643A
(en)
*
|
1979-07-05 |
1981-12-01 |
Pfizer Inc. |
Sulfonamide compositions
|
CA1163197A
(en)
*
|
1980-04-10 |
1984-03-06 |
Herman Horn |
Injectable oxytetracycline compositions
|
US4386083A
(en)
*
|
1980-04-10 |
1983-05-31 |
Walter Hacke |
Injectable oxytetracycline compositions
|
US4399127A
(en)
*
|
1980-04-10 |
1983-08-16 |
Diamond Shamrock Corporation |
Injectable oxytetracycline compositions
|
US4374826A
(en)
*
|
1980-07-21 |
1983-02-22 |
Pfizer Inc. |
Sulfonamide compositions
|
NL178941C
(nl)
*
|
1982-06-15 |
1986-06-16 |
Aesculaap Bv |
Werkwijze voor de bereiding van een waterig oxytetracyclinepreparaat.
|
US4769232A
(en)
*
|
1984-03-22 |
1988-09-06 |
Pfizer Inc. |
Parenteral formulations of indolmycin
|
IE74244B1
(en)
*
|
1985-10-01 |
1997-07-16 |
Bimeda Res Dev Ltd |
A process for preparing an antibiotic composition
|
HU194493B
(en)
*
|
1985-11-27 |
1988-02-29 |
Chinoin Gyogyszer Es Vegyeszet |
Process for preparing primycin-containing colloidal basic gel and compositions comprising the same
|
FR2608044B1
(fr)
*
|
1986-12-10 |
1992-09-11 |
Sogeval |
Composition antibiotique aqueuse a usage veterinaire
|
US4906475A
(en)
*
|
1988-02-16 |
1990-03-06 |
Paco Pharmaceutical Services |
Estradiol transdermal delivery system
|
US6756365B2
(en)
*
|
1991-11-06 |
2004-06-29 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
EP0626171A1
(de)
*
|
1993-05-26 |
1994-11-30 |
Winfried Dörnhöfer |
Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
|
ES2130069B1
(es)
*
|
1997-04-10 |
2000-03-01 |
Basf Labiana S A |
Preparacion farmaceutica con liberacion retardada del producto activo.
|
US20020077276A1
(en)
*
|
1999-04-27 |
2002-06-20 |
Fredeking Terry M. |
Compositions and methods for treating hemorrhagic virus infections and other disorders
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
US8106225B2
(en)
*
|
1999-09-14 |
2012-01-31 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
EP1666453A1
(en)
|
1999-09-14 |
2006-06-07 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
AU2001228454A1
(en)
*
|
2000-01-13 |
2001-07-24 |
Merck Patent G.M.B.H |
Pharmaceutical preparations containing 2-pyrrolidone as the dissolving intermediary
|
CA2397863A1
(en)
|
2000-01-24 |
2001-07-26 |
Trustees Of Tufts College |
Tetracycline compounds for treatment of cryptosporidium parvum related disorders
|
ES2288945T3
(es)
*
|
2000-03-31 |
2008-02-01 |
Trustees Of Tufts College |
Compuestos de tetraciclina 7 y 9-carbamato, urea, tiourea, tiocarbamato y heteroaril-amino sustituidos.
|
US6642270B2
(en)
*
|
2000-05-15 |
2003-11-04 |
Paratek Pharmaceuticals, Inc. |
7-substituted fused ring tetracycline compounds
|
US20040224927A1
(en)
*
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
AU2001268475A1
(en)
*
|
2000-06-16 |
2002-01-02 |
Trustees Of Tufts College |
7-phenyl-substituted tetracycline compounds
|
US20020132798A1
(en)
*
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
EP1303479B1
(en)
|
2000-07-07 |
2011-04-06 |
Trustees Of Tufts College |
7-, 8- and 9-substituted tetracycline compounds
|
US7094806B2
(en)
*
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
DK1679305T3
(da)
|
2000-07-07 |
2012-05-29 |
Tufts College |
9-substituerede minocyclinforbindelser
|
US6818635B2
(en)
|
2000-07-07 |
2004-11-16 |
Paratek Pharmaceuticals, Inc. |
7-substituted tetracycline compounds
|
MXPA03000036A
(es)
|
2000-07-07 |
2003-07-14 |
Tufts College |
Compuestos de metaciclina sustituidos en posicion 13.
|
US20050143353A1
(en)
*
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
AU2002250331A1
(en)
|
2001-03-13 |
2002-09-24 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
JP2005506291A
(ja)
|
2001-03-13 |
2005-03-03 |
パラテック ファーマシューティカルズ, インク. |
7,9−置換テトラサイクリン化合物
|
US7553828B2
(en)
|
2001-03-13 |
2009-06-30 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl substituted minocycline compounds
|
EP1241160A1
(en)
*
|
2001-03-13 |
2002-09-18 |
Glaxo Group Limited |
Tetracycline derivatives and their use as antibiotic agents
|
JP2005504722A
(ja)
|
2001-03-14 |
2005-02-17 |
パラテック ファーマシューティカルズ インコーポレイテッド |
相乗的抗真菌薬剤としての置換テトラサイクリン化合物
|
US6841546B2
(en)
|
2001-03-14 |
2005-01-11 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as antifungal agents
|
AU2002254714C1
(en)
|
2001-04-24 |
2010-01-07 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
US8088820B2
(en)
*
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
US20030181371A1
(en)
*
|
2001-12-28 |
2003-09-25 |
Angiotech Pharmaceuticals, Inc. |
Compositions and methods of using collajolie
|
EP2311796A1
(en)
*
|
2002-01-08 |
2011-04-20 |
Paratek Pharmaceuticals, Inc. |
4-dedimethylamino tetracycline compounds
|
CA2478335C
(en)
|
2002-03-08 |
2011-05-10 |
Paratek Pharmaceuticals, Inc. |
Amino-methyl substituted tetracycline compounds
|
EP1503981A4
(en)
|
2002-03-21 |
2007-08-15 |
Paratek Pharm Innc |
SUBSTITUTED TETRACYCLINE COMPOUNDS
|
US6958161B2
(en)
|
2002-04-12 |
2005-10-25 |
F H Faulding & Co Limited |
Modified release coated drug preparation
|
WO2004006850A2
(en)
|
2002-07-12 |
2004-01-22 |
Paratek Pharmaceuticals, Inc |
3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS
|
CA2502464A1
(en)
|
2002-10-24 |
2004-05-06 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
CA2509060A1
(en)
*
|
2002-12-27 |
2004-07-22 |
Angiotech International Ag |
Compositions and methods of using collagen and mmpi
|
EP2298322A3
(en)
|
2003-07-09 |
2011-05-11 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
CA2531732C
(en)
|
2003-07-09 |
2012-04-10 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
US20060287283A1
(en)
*
|
2003-07-09 |
2006-12-21 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
CA2533150C
(en)
*
|
2003-07-25 |
2013-03-12 |
Warner Chilcott Company, Inc. |
A doxycycline metal complex in a solid dosage form
|
JP5010284B2
(ja)
*
|
2004-01-15 |
2012-08-29 |
パラテック ファーマシューティカルズ インコーポレイテッド |
テトラサイクリン化合物の芳香族a環誘導体
|
TWI261038B
(en)
*
|
2004-08-11 |
2006-09-01 |
Bo-Cheng Chen |
Bicycle gear-shifting handgrip
|
EP2284155A3
(en)
|
2004-10-25 |
2011-10-12 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
AU2005299294B2
(en)
*
|
2004-10-25 |
2012-06-07 |
Paratek Pharmaceuticals, Inc. |
4-aminotetracyclines and methods of use thereof
|
US20060183719A1
(en)
*
|
2005-01-21 |
2006-08-17 |
Devries Tina M |
Tetracycline metal complex in a solid dosage form
|
CA2597212A1
(en)
*
|
2005-02-04 |
2006-08-10 |
Paratek Pharmaceuticals, Inc. |
11a, 12-derivatives of tetracycline compounds
|
US20080241235A1
(en)
*
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US8722650B1
(en)
|
2005-06-24 |
2014-05-13 |
Medicis Pharmaceutical Corporation |
Extended-release minocycline dosage forms
|
US7541347B2
(en)
*
|
2007-04-02 |
2009-06-02 |
Medicis Pharmaceutical Coropration |
Minocycline oral dosage forms for the treatment of acne
|
US7544373B2
(en)
*
|
2007-04-02 |
2009-06-09 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US7919483B2
(en)
*
|
2005-06-24 |
2011-04-05 |
Medicis Pharmaceutical Corporation |
Method for the treatment of acne
|
US8252776B2
(en)
|
2007-04-02 |
2012-08-28 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US20080242642A1
(en)
*
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
EP1910273A2
(en)
*
|
2005-07-21 |
2008-04-16 |
Paratek Pharmaceuticals, Inc. |
10-substituted tetracyclines and methods of use thereof
|
CA2639406A1
(en)
*
|
2006-01-24 |
2007-08-02 |
Paratek Pharmaceuticals, Inc. |
Methods of increasing oral bioavailability of tetracyclines
|
EP2007713A2
(en)
*
|
2006-04-17 |
2008-12-31 |
Teva Pharmaceutical Industries Ltd |
Isolation of tetracycline derivatives
|
US8198470B2
(en)
*
|
2006-04-24 |
2012-06-12 |
Teva Pharmaceutical Industries Ltd. |
Crystalline form II of tigecycline and processes for preparation thereof
|
PT2016045E
(pt)
*
|
2006-04-24 |
2015-02-05 |
Teva Pharma |
Forma cristalina de tigeciclina e processos para a sua preparação
|
AU2007249695A1
(en)
*
|
2006-05-15 |
2007-11-22 |
Paratek Pharmaceuticals, Inc. |
Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
|
US8440646B1
(en)
|
2006-10-11 |
2013-05-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of Bacillus anthracis infections
|
US8318706B2
(en)
|
2006-12-21 |
2012-11-27 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
AU2007338681B2
(en)
|
2006-12-21 |
2013-09-26 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of inflammatory skin disorders
|
US20080241197A1
(en)
*
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline dosage forms for the treatment of acne
|
CA2688725A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Paratek Pharmaceuticals, Inc. |
Methods for treating spinal muscular atrophy using tetracycline compounds
|
EP2213655A1
(en)
|
2007-04-27 |
2010-08-04 |
Paratek Pharmaceuticals, Inc. |
Methods For Purifying Aminoalkyl Tetracycline Compounds
|
KR20100042276A
(ko)
|
2007-07-06 |
2010-04-23 |
파라테크 파마슈티컬스, 인크. |
치환 테트라사이클린 화합물의 합성방법
|
EP2262754A4
(en)
|
2008-03-05 |
2012-03-14 |
Paratek Pharm Innc |
MINOCYCLINE COMPOUNDS AND METHODS OF USE THEREOF
|
PT2271348T
(pt)
|
2008-03-28 |
2018-04-16 |
Paratek Pharm Innc |
Formulação de comprimido oral de composto de tetraciclina
|
JP2011517697A
(ja)
*
|
2008-04-14 |
2011-06-16 |
パラテック ファーマシューティカルズ インコーポレイテッド |
置換テトラサイクリン化合物
|
TW202021946A
(zh)
*
|
2008-05-23 |
2020-06-16 |
美商派洛泰克藥物股份有限公司 |
四環素化合物之甲苯磺酸鹽及同素異形體
|
WO2010017310A1
(en)
|
2008-08-06 |
2010-02-11 |
Medicis Pharmaceutical Corporation |
Method for the treatment of acne and certain dosage forms thereof
|
AU2009292986A1
(en)
*
|
2008-09-19 |
2010-03-25 |
Paratek Pharmaceuticals, Inc. |
Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment
|
US20120121706A1
(en)
|
2009-04-10 |
2012-05-17 |
Tufts Medical Center, Inc. |
PAR-1 Activation by Metalloproteinase-1 (MMP-1)
|
JP6025712B2
(ja)
|
2010-05-12 |
2016-11-16 |
レンペックス・ファーマシューティカルズ・インコーポレイテッド |
テトラサイクリン組成物
|
SI2707003T1
(sl)
|
2011-05-12 |
2019-10-30 |
Paratek Pharm Innc |
Kristalinične soli amida (4S,4AS,5AR,12AS)-4-dimetilamino-3,10,12,12A-tetrahidroksi-7-((metoksi (metil)amino)-metil)-1,11-diokso-1,4,4A,5,5A,6,11,12A-oktahidro-naftacen -2-karboksilne kisline in postopki za uporabo le-teh
|
US9561241B1
(en)
|
2011-06-28 |
2017-02-07 |
Medicis Pharmaceutical Corporation |
Gastroretentive dosage forms for minocycline
|
WO2015021387A2
(en)
*
|
2013-08-09 |
2015-02-12 |
Britt George N |
Formulations for control and prevention of periodontal and perimplant diseases and other diseases and conditions of the mouth, and supra and sub-gingival delivery methods and systems for such formulations
|
CN103536530A
(zh)
*
|
2013-10-30 |
2014-01-29 |
王玉万 |
盐酸多西环素长效注射剂及制备方法
|
US9918998B2
(en)
|
2015-03-23 |
2018-03-20 |
BioPharmX, Inc. |
Pharmaceutical tetracycline composition for dermatological use
|
CN104721133B
(zh)
*
|
2015-04-14 |
2018-05-18 |
四川美嘉龙生物科技有限公司 |
一种土霉素制剂及制备方法
|
EP3534908A4
(en)
|
2016-11-01 |
2020-05-27 |
Paratek Pharmaceuticals, Inc. |
9-AMINOMETHYL-MINOCYCLINE COMPOUNDS AND USE THEREOF IN THE TREATMENT OF AMBULANTLY ACQUIRED BACTERIAL PNEUMONIA (CABP)
|
KR102662461B1
(ko)
|
2017-07-21 |
2024-04-30 |
알미랄 엘엘씨 |
비염증성 병변의 치료
|
WO2019106036A1
(en)
|
2017-11-28 |
2019-06-06 |
C-Lecta Gmbh |
Method for producing trehalose employing a trehalose phosphorylase variant
|
US11426351B2
(en)
|
2019-12-26 |
2022-08-30 |
Sunstar Inc. |
Process for producing a pharmaceutical composition containing micro particles
|