HK30096A - Heteroatoms-containing tricyclic compounds - Google Patents
Heteroatoms-containing tricyclic compoundsInfo
- Publication number
- HK30096A HK30096A HK30096A HK30096A HK30096A HK 30096 A HK30096 A HK 30096A HK 30096 A HK30096 A HK 30096A HK 30096 A HK30096 A HK 30096A HK 30096 A HK30096 A HK 30096A
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- heteroatoms
- tricyclic compounds
- containing tricyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3937336 | 1989-11-09 | ||
DE3938132 | 1989-11-16 | ||
DE3942831 | 1989-12-23 | ||
DE3942833 | 1989-12-23 | ||
DE4006819 | 1990-03-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK30096A true HK30096A (en) | 1996-02-23 |
Family
ID=27511355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK30096A HK30096A (en) | 1989-11-09 | 1996-02-15 | Heteroatoms-containing tricyclic compounds |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0427680B1 (xx) |
JP (1) | JP2750302B2 (xx) |
KR (1) | KR0166074B1 (xx) |
AT (1) | ATE126803T1 (xx) |
AU (1) | AU640963B2 (xx) |
CA (1) | CA2029694C (xx) |
DE (2) | DE69021833T2 (xx) |
DK (1) | DK0427680T3 (xx) |
ES (1) | ES2077663T3 (xx) |
GR (1) | GR3017858T3 (xx) |
HK (1) | HK30096A (xx) |
HU (1) | HU210900A9 (xx) |
IE (1) | IE69974B1 (xx) |
LU (1) | LU91021I2 (xx) |
LV (1) | LV11621B (xx) |
MY (1) | MY111430A (xx) |
NL (1) | NL300134I2 (xx) |
NZ (1) | NZ235991A (xx) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0356399A3 (en) * | 1988-08-26 | 1991-03-20 | Sandoz Ag | Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them |
EP0402931A1 (en) * | 1989-06-14 | 1990-12-19 | Sandoz Ltd. | Heteroatoms-containing tricyclic compounds |
US5208228A (en) * | 1989-11-13 | 1993-05-04 | Merck & Co., Inc. | Aminomacrolides and derivatives having immunosuppressive activity |
MY110418A (en) * | 1990-07-02 | 1998-05-30 | Novartis Ag | Heteroatoms-containing tricyclic compounds. |
US5143918A (en) * | 1990-10-11 | 1992-09-01 | Merck & Co., Inc. | Halomacrolides and derivatives having immunosuppressive activity |
EP0480623A1 (en) * | 1990-10-11 | 1992-04-15 | Merck & Co. Inc. | New halomacrolides and derivatives having immunosuppressive activity |
US5250678A (en) * | 1991-05-13 | 1993-10-05 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
WO1992020688A1 (en) * | 1991-05-13 | 1992-11-26 | Merck & Co., Inc. | Amino o-aryl, o-alkyl, o-alkenyl and o-alkynyl macrolides |
US5162334A (en) * | 1991-05-13 | 1992-11-10 | Merck & Co., Inc. | Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity |
US5565560A (en) * | 1991-05-13 | 1996-10-15 | Merck & Co., Inc. | O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
US5189042A (en) * | 1991-08-22 | 1993-02-23 | Merck & Co. Inc. | Fluoromacrolides having immunosuppressive activity |
US5708002A (en) * | 1991-09-05 | 1998-01-13 | Abbott Laboratories | Macrocyclic immunomodulators |
EP0642516B1 (en) * | 1991-09-05 | 2002-06-05 | Abbott Laboratories | Macrocyclic immunomodulators |
US5208241A (en) * | 1991-09-09 | 1993-05-04 | Merck & Co., Inc. | N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity |
DK0636136T3 (da) * | 1992-03-02 | 1997-12-22 | Pfizer | 2-aminosukkerderivater af makrolider |
CA2091194A1 (en) * | 1992-04-08 | 1993-10-09 | Richard D. Connell | 2-oxo-ethyl derivatives as immunosuppressants |
US5284877A (en) * | 1992-06-12 | 1994-02-08 | Merck & Co., Inc. | Alkyl and alkenyl macrolides having immunosuppressive activity |
US5284840A (en) * | 1992-06-12 | 1994-02-08 | Merck & Co., Inc. | Alkylidene macrolides having immunosuppressive activity |
CH686761A5 (de) * | 1993-05-27 | 1996-06-28 | Sandoz Ag | Galenische Formulierungen. |
US5612350A (en) * | 1993-11-30 | 1997-03-18 | Abbott Laboratories | Macrocyclic immunomodulators with novel cyclohexyl ring replacements |
WO1995015328A1 (en) * | 1993-11-30 | 1995-06-08 | Abbott Laboratories | Macrocyclic immunomodulators with novel cyclohexyl ring replacements |
US5880280A (en) * | 1994-06-15 | 1999-03-09 | Merck & Co., Inc. | Aryl, alkyl, alkenyl and alkynylmacrolides having immunosuppressive activity |
US5550233A (en) * | 1994-06-21 | 1996-08-27 | Merck & Co., Inc. | Aryl, alkyl, alkenyl and alkynylmacrolides having immunosuppressive activity |
US5693648A (en) * | 1994-09-30 | 1997-12-02 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity |
US5545734A (en) * | 1994-10-25 | 1996-08-13 | Merck & Co., Inc. | Aryl and heteroaryl macrolides having immunosuppressive activity |
IL115742A (en) | 1994-10-26 | 2000-06-01 | Novartis Ag | Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant |
EP0786986B1 (en) * | 1994-10-26 | 2002-03-20 | Novartis AG | Use of an unsaturated fatty alcohol |
GB9618952D0 (en) * | 1996-09-11 | 1996-10-23 | Sandoz Ltd | Process |
AR004480A1 (es) * | 1995-04-06 | 1998-12-16 | Amico Derin C D | Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen |
JP3282945B2 (ja) * | 1995-06-07 | 2002-05-20 | 松下電器産業株式会社 | スピンドルモータ |
FR2736550B1 (fr) * | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
GB9601120D0 (en) * | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
GB9713730D0 (en) * | 1997-06-30 | 1997-09-03 | Ciba Geigy Ag | Organic compounds |
MEP30008A (en) | 1998-03-26 | 2010-10-10 | Astellas Pharma Inc | Sustained release preparations |
GB9826656D0 (en) | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
GB0003932D0 (en) * | 2000-02-18 | 2000-04-12 | Novartis Ag | Pharmaceutical compositions |
GB0008785D0 (en) | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
GB0012383D0 (en) | 2000-05-22 | 2000-07-12 | Novartis Ag | Organic compounds |
AR033151A1 (es) * | 2001-04-12 | 2003-12-03 | Sucampo Pharmaceuticals Inc | Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares |
GB0125443D0 (en) * | 2001-10-23 | 2001-12-12 | Novartis Ag | Organic Compounds |
CA2492989C (en) | 2002-07-23 | 2012-11-20 | Novartis Ag | Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent |
AU2003283399B2 (en) * | 2002-11-15 | 2007-04-19 | Novartis Ag | Drug delivery system |
CA2513731A1 (en) * | 2003-02-10 | 2004-08-19 | Novartis Ag | Pharmaceutical combinations comprising corticoids and immunosuppressants for treating corticoid- and/or calcineurin inhibitors-resistant diseases |
AR043504A1 (es) * | 2003-03-17 | 2005-08-03 | Novartis Ag | Composiciones farmaceuticas que comprenden rapamicina para el tratamiento de enfermedades inflamatorias |
EP1729729B1 (en) | 2004-03-23 | 2014-04-23 | Novartis AG | Pharmaceutical compositions |
GT200500282A (es) * | 2004-10-12 | 2006-05-04 | Heteroatomos conteniendo compuestos triciclicos. | |
EP1817314A1 (en) * | 2004-12-01 | 2007-08-15 | Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság | Non-hygroscopic and powdery amorphous pimecrolimus |
TW200837067A (en) * | 2006-11-06 | 2008-09-16 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Ascomycin and pimecrolimus having reduced levels of desmethylascomycin and 32-deoxy-32-epichloro-desmethylascomycin respectively, and methods for preparation thereof |
US20100087550A1 (en) | 2008-10-06 | 2010-04-08 | Zora Marlowe | Formulations with a Tertiary Amine Oxide |
US20100106128A1 (en) | 2008-10-23 | 2010-04-29 | Shane Mao | Contact lens cases for delivery of ophthalmic agents |
IT1394309B1 (it) * | 2009-05-22 | 2012-06-06 | Poli Ind Chimica Spa | Nuovo approccio chimico-enzimatico alla sintesi del pimecrolimus |
GB0914589D0 (en) * | 2009-08-20 | 2009-09-30 | Biotica Tech Ltd | Novel compounds and methods for their production |
US10143682B2 (en) | 2014-10-28 | 2018-12-04 | Koushi Yamaguchi | Medicine for improving state of pregnancy, and use thereof |
EP3178824A1 (en) | 2015-12-08 | 2017-06-14 | Medichem, S.A. | Process for preparing pimecrolimus |
CN106074367A (zh) * | 2016-07-20 | 2016-11-09 | 中山大学中山眼科中心 | 含fk506类化合物/fkbp蛋白二聚体的药物组合物及其制备方法 |
ES2906158T3 (es) | 2017-05-01 | 2022-04-13 | Meda Pharma Gmbh & Co Kg | Proceso para convertir ascomicina bruta en pimecrolimus purificado |
JP7465806B2 (ja) | 2018-08-10 | 2024-04-11 | 晃史 山口 | 母体と胎児との関係における液性免疫関連疾患の治療薬 |
AU2019401108A1 (en) | 2018-12-18 | 2021-07-01 | Koushi Yamaguchi | Agent for improving infertility, recurrent miscarriage, and state of pregnancy |
EP3741367A1 (en) | 2019-05-21 | 2020-11-25 | Premark Pharma GmbH | Treatment of ocular disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
US4650803A (en) * | 1985-12-06 | 1987-03-17 | University Of Kansas | Prodrugs of rapamycin |
EP0346427B1 (en) * | 1987-12-09 | 1995-03-29 | FISONS plc | Macrocyclic compounds |
EP0402931A1 (en) * | 1989-06-14 | 1990-12-19 | Sandoz Ltd. | Heteroatoms-containing tricyclic compounds |
PT98990A (pt) * | 1990-09-19 | 1992-08-31 | American Home Prod | Processo para a preparacao de esteres de acidos carboxilicos de rapamicina |
-
1990
- 1990-11-07 AU AU65843/90A patent/AU640963B2/en not_active Expired
- 1990-11-07 DE DE69021833T patent/DE69021833T2/de not_active Expired - Lifetime
- 1990-11-07 NZ NZ235991A patent/NZ235991A/xx unknown
- 1990-11-07 DE DE2002199040 patent/DE10299040I2/de active Active
- 1990-11-07 AT AT90810854T patent/ATE126803T1/de active
- 1990-11-07 EP EP90810854A patent/EP0427680B1/en not_active Expired - Lifetime
- 1990-11-07 ES ES90810854T patent/ES2077663T3/es not_active Expired - Lifetime
- 1990-11-07 DK DK90810854.1T patent/DK0427680T3/da active
- 1990-11-08 KR KR1019900018016A patent/KR0166074B1/ko not_active IP Right Cessation
- 1990-11-08 JP JP2305894A patent/JP2750302B2/ja not_active Expired - Lifetime
- 1990-11-08 IE IE402390A patent/IE69974B1/en not_active IP Right Cessation
- 1990-11-08 MY MYPI90001975A patent/MY111430A/en unknown
- 1990-11-09 CA CA002029694A patent/CA2029694C/en not_active Expired - Lifetime
-
1995
- 1995-06-02 HU HU95P/P00161P patent/HU210900A9/hu active Protection Beyond IP Right Term
- 1995-10-25 GR GR950402962T patent/GR3017858T3/el unknown
-
1996
- 1996-02-15 HK HK30096A patent/HK30096A/xx not_active IP Right Cessation
- 1996-07-17 LV LVP-96-253A patent/LV11621B/lv unknown
-
2003
- 2003-04-23 LU LU91021C patent/LU91021I2/fr unknown
- 2003-09-05 NL NL300134C patent/NL300134I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
KR0166074B1 (ko) | 1999-01-15 |
KR910009711A (ko) | 1991-06-28 |
CA2029694C (en) | 2001-05-08 |
AU640963B2 (en) | 1993-09-09 |
LV11621A (lv) | 1996-12-20 |
ATE126803T1 (de) | 1995-09-15 |
NZ235991A (en) | 1993-05-26 |
NL300134I1 (nl) | 2003-11-03 |
DE10299040I2 (de) | 2006-08-24 |
LU91021I2 (fr) | 2003-06-24 |
CA2029694A1 (en) | 1991-05-10 |
DE10299040I1 (de) | 2003-02-20 |
HU210900A9 (en) | 1995-09-28 |
MY111430A (en) | 2000-05-31 |
NL300134I2 (nl) | 2004-05-03 |
JP2750302B2 (ja) | 1998-05-13 |
EP0427680A1 (en) | 1991-05-15 |
IE69974B1 (en) | 1996-10-16 |
ES2077663T3 (es) | 1995-12-01 |
DE69021833T2 (de) | 1996-03-21 |
EP0427680B1 (en) | 1995-08-23 |
DE69021833D1 (de) | 1995-09-28 |
JPH03223291A (ja) | 1991-10-02 |
IE904023A1 (en) | 1991-05-22 |
DK0427680T3 (da) | 1995-12-18 |
GR3017858T3 (en) | 1996-01-31 |
LV11621B (en) | 1997-04-20 |
AU6584390A (en) | 1991-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20101106 |