HK1252009A1 - 針對白細胞介素36受體(il-36r)的抗體 - Google Patents

針對白細胞介素36受體(il-36r)的抗體

Info

Publication number
HK1252009A1
HK1252009A1 HK18111338.8A HK18111338A HK1252009A1 HK 1252009 A1 HK1252009 A1 HK 1252009A1 HK 18111338 A HK18111338 A HK 18111338A HK 1252009 A1 HK1252009 A1 HK 1252009A1
Authority
HK
Hong Kong
Prior art keywords
receptor
directed against
antibodies directed
against interleukin
interleukin
Prior art date
Application number
HK18111338.8A
Other languages
English (en)
Inventor
P‧鮑爾斯
A‧J‧麥克奈特
D‧J‧金
M‧隆代伊
Original Assignee
安奈普泰斯生物有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 安奈普泰斯生物有限公司 filed Critical 安奈普泰斯生物有限公司
Publication of HK1252009A1 publication Critical patent/HK1252009A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK18111338.8A 2015-04-15 2018-09-04 針對白細胞介素36受體(il-36r)的抗體 HK1252009A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562147824P 2015-04-15 2015-04-15

Publications (1)

Publication Number Publication Date
HK1252009A1 true HK1252009A1 (zh) 2019-05-10

Family

ID=57126337

Family Applications (2)

Application Number Title Priority Date Filing Date
HK18110434.3A HK1250941A1 (zh) 2015-04-15 2018-08-14 針對白細胞介素36受體(il-36r)的抗體
HK18111338.8A HK1252009A1 (zh) 2015-04-15 2018-09-04 針對白細胞介素36受體(il-36r)的抗體

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK18110434.3A HK1250941A1 (zh) 2015-04-15 2018-08-14 針對白細胞介素36受體(il-36r)的抗體

Country Status (16)

Country Link
US (3) US10526410B2 (zh)
EP (2) EP3283110B1 (zh)
JP (3) JP6913026B2 (zh)
KR (1) KR102666920B1 (zh)
CN (2) CN107847590B (zh)
AU (1) AU2016248208B2 (zh)
BR (1) BR112017022086A2 (zh)
CA (1) CA2982555A1 (zh)
DK (1) DK3283110T3 (zh)
ES (1) ES2914243T3 (zh)
HK (2) HK1250941A1 (zh)
MX (2) MX2017013080A (zh)
PL (1) PL3283110T3 (zh)
RU (1) RU2745898C2 (zh)
SG (1) SG11201708061TA (zh)
WO (1) WO2016168542A1 (zh)

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PL2780373T3 (pl) 2011-11-16 2020-03-31 Boehringer Ingelheim International Gmbh Przeciwciała anty il-36r
WO2016168542A1 (en) * 2015-04-15 2016-10-20 Anaptysbio, Inc. Antibodies directed against interleukin 36 receptor (il-36r)
CN110461877A (zh) * 2017-03-27 2019-11-15 勃林格殷格翰国际有限公司 抗il-36r抗体联合治疗
EP3400962A1 (en) 2017-05-09 2018-11-14 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. Inhibitors of il-38 for use in treating and/or preventing cancer in a subject
BR112020016401A2 (pt) * 2018-03-14 2020-12-15 Boehringer Ingelheim International Gmbh Uso de anticorpos anti-il-36r para o tratamento de doença inflamatória intestinal
US20190284285A1 (en) * 2018-03-14 2019-09-19 Boehringer Ingelheim International Gmbh Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis
WO2020018503A2 (en) * 2018-07-16 2020-01-23 Regeneron Pharmaceuticals, Inc. Anti-il36r antibodies
CN110818796B (zh) * 2018-08-09 2022-11-08 东莞市朋志生物科技有限公司 一种抗人ca153蛋白的重组抗体
EA202191656A1 (ru) 2018-12-21 2021-10-26 23Эндми, Инк. Анти-il-36 антитела и способы их применения
US11730812B2 (en) * 2019-03-08 2023-08-22 Boehringer Ingelheim International Gmbh Anti-IL-36R antibody formulations
US20220162326A1 (en) * 2019-05-13 2022-05-26 Regeneron Pharmaceuticals, Inc. Anti-il36r antibodies
JP2022543658A (ja) 2019-08-07 2022-10-13 アクアラン セラピューティクス コーポレーション 抗ｎａｍｐｔ抗体及びその用途
WO2021112196A1 (ja) * 2019-12-05 2021-06-10 学校法人東京薬科大学 筋組織の減少を抑制するための組成物
AR120913A1 (es) * 2019-12-27 2022-03-30 Teijin Pharma Ltd Anticuerpo que inhibe específicamente la señalización de il-36r
WO2022015920A1 (en) * 2020-07-17 2022-01-20 Boehringer Ingelheim International Gmbh Anti-il-36r antibodies for the treatment of neutrophilic dermatoses
WO2022026829A1 (en) 2020-07-30 2022-02-03 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for skin toxicity
WO2022026832A1 (en) 2020-07-30 2022-02-03 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for ichthyosis
WO2022150642A1 (en) 2021-01-08 2022-07-14 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa
WO2022150644A1 (en) 2021-01-08 2022-07-14 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for acne
JP2024512384A (ja) 2021-03-12 2024-03-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 汎発型膿疱性乾癬における抗ｉｌ－３６ｒ抗体による処置に関連したバイオマーカー
US20240216506A1 (en) * 2021-05-12 2024-07-04 Anaptysbio, Inc. Antibody composition
WO2023285362A1 (en) 2021-07-12 2023-01-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of il-36 inhibitors for the treatment of netherton syndrome
TW202323293A (zh) * 2021-10-29 2023-06-16 新加坡商創響私人有限公司 新型抗ｉｌ－３６ｒ抗體
CN115724975A (zh) * 2022-10-20 2023-03-03 江苏荃信生物医药股份有限公司 抗人白介素36受体单克隆抗体及其应用

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AU650085B2 (en) 1990-11-13 1994-06-09 Immunex Corporation Bifunctional selectable fusion genes
WO1994028143A1 (en) 1993-05-21 1994-12-08 Targeted Genetics Corporation Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene
US5814618A (en) 1993-06-14 1998-09-29 Basf Aktiengesellschaft Methods for regulating gene expression
US5464758A (en) 1993-06-14 1995-11-07 Gossen; Manfred Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
AU2001233212A1 (en) 2000-02-02 2001-08-14 Schering Corporation Mammalian cytokines; receptors; related reagents and methods
FR2814642B1 (fr) 2000-10-03 2005-07-01 Ass Pour Le Dev De La Rech En Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
WO2003048731A2 (en) 2001-12-03 2003-06-12 Abgenix, Inc. Antibody categorization based on binding characteristics
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WO2008103475A1 (en) 2007-02-20 2008-08-28 Anaptysbio, Inc. Somatic hypermutation systems
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WO2013016220A1 (en) * 2011-07-22 2013-01-31 Amgen Inc. Il-17 receptor a is required for il-17c biology
PL2780373T3 (pl) * 2011-11-16 2020-03-31 Boehringer Ingelheim International Gmbh Przeciwciała anty il-36r
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WO2016168542A1 (en) * 2015-04-15 2016-10-20 Anaptysbio, Inc. Antibodies directed against interleukin 36 receptor (il-36r)
CN110461877A (zh) 2017-03-27 2019-11-15 勃林格殷格翰国际有限公司 抗il-36r抗体联合治疗
BR112020016401A2 (pt) 2018-03-14 2020-12-15 Boehringer Ingelheim International Gmbh Uso de anticorpos anti-il-36r para o tratamento de doença inflamatória intestinal
US20190284285A1 (en) 2018-03-14 2019-09-19 Boehringer Ingelheim International Gmbh Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis
WO2020018503A2 (en) 2018-07-16 2020-01-23 Regeneron Pharmaceuticals, Inc. Anti-il36r antibodies
EA202191656A1 (ru) 2018-12-21 2021-10-26 23Эндми, Инк. Анти-il-36 антитела и способы их применения
EP3902604A1 (en) 2018-12-27 2021-11-03 Boehringer Ingelheim International GmbH Anti-il-36r antibodies for treatment of palmoplantar pustulosis
US11730812B2 (en) 2019-03-08 2023-08-22 Boehringer Ingelheim International Gmbh Anti-IL-36R antibody formulations
CN113316587B (zh) 2019-05-20 2024-03-26 南通壹宸生物医药科技有限公司 一种双特异性分子及其制备与用途

Also Published As

Publication number Publication date
WO2016168542A1 (en) 2016-10-20
CN107847590A (zh) 2018-03-27
EP4176900A1 (en) 2023-05-10
HK1250941A1 (zh) 2019-01-18
US10526410B2 (en) 2020-01-07
JP2018512157A (ja) 2018-05-17
SG11201708061TA (en) 2017-10-30
AU2016248208B2 (en) 2022-03-24
CA2982555A1 (en) 2016-10-20
DK3283110T3 (da) 2022-05-23
JP6913026B2 (ja) 2021-08-04
US20180094065A1 (en) 2018-04-05
CN107847590B (zh) 2022-07-26
CN115925932A (zh) 2023-04-07
US20210388095A1 (en) 2021-12-16
MX2023001791A (es) 2023-03-10
JP2023040236A (ja) 2023-03-22
US20200087408A1 (en) 2020-03-19
RU2017139481A3 (zh) 2019-09-19
EP3283110A1 (en) 2018-02-21
JP2021118710A (ja) 2021-08-12
EP3283110A4 (en) 2019-02-27
ES2914243T3 (es) 2022-06-08
PL3283110T3 (pl) 2022-06-27
JP7212098B2 (ja) 2023-01-24
KR20180002687A (ko) 2018-01-08
RU2745898C2 (ru) 2021-04-02
RU2017139481A (ru) 2019-05-15
KR102666920B1 (ko) 2024-05-20
AU2016248208A1 (en) 2017-11-09
EP3283110B1 (en) 2022-04-20
MX2017013080A (es) 2018-02-09
BR112017022086A2 (pt) 2018-07-03
US11130814B2 (en) 2021-09-28

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