HK1245804A1 - 用於治療pvns的抗csf1r抗體 - Google Patents

用於治療pvns的抗csf1r抗體

Info

Publication number
HK1245804A1
HK1245804A1 HK18105046.3A HK18105046A HK1245804A1 HK 1245804 A1 HK1245804 A1 HK 1245804A1 HK 18105046 A HK18105046 A HK 18105046A HK 1245804 A1 HK1245804 A1 HK 1245804A1
Authority
HK
Hong Kong
Prior art keywords
csf1r antibodies
pvns
treating
treating pvns
csf1r
Prior art date
Application number
HK18105046.3A
Other languages
English (en)
Inventor
Robert Sikorski
Julie Hambleton
Nilacantan Sankar
Original Assignee
Five Prime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics Inc filed Critical Five Prime Therapeutics Inc
Publication of HK1245804A1 publication Critical patent/HK1245804A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
HK18105046.3A 2014-12-22 2018-04-18 用於治療pvns的抗csf1r抗體 HK1245804A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462095297P 2014-12-22 2014-12-22
US201562163251P 2015-05-18 2015-05-18
PCT/US2015/067012 WO2016106180A1 (en) 2014-12-22 2015-12-21 Anti-csf1r antibodies for treating pvns

Publications (1)

Publication Number Publication Date
HK1245804A1 true HK1245804A1 (zh) 2018-08-31

Family

ID=55135539

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105046.3A HK1245804A1 (zh) 2014-12-22 2018-04-18 用於治療pvns的抗csf1r抗體

Country Status (16)

Country Link
US (3) US10040858B2 (zh)
EP (1) EP3237447B1 (zh)
JP (1) JP6797801B2 (zh)
KR (1) KR20170096187A (zh)
CN (1) CN107257806B (zh)
AU (1) AU2015369854B2 (zh)
BR (1) BR112017013111A2 (zh)
CA (1) CA2969341C (zh)
EA (1) EA201791421A1 (zh)
ES (1) ES2843586T3 (zh)
HK (1) HK1245804A1 (zh)
IL (1) IL252716A0 (zh)
MX (1) MX2017008218A (zh)
SG (1) SG11201704792UA (zh)
TW (1) TW201630937A (zh)
WO (1) WO2016106180A1 (zh)

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JP7461741B2 (ja) 2016-06-20 2024-04-04 カイマブ・リミテッド 抗pd-l1およびil-2サイトカイン
CN110709422B (zh) 2017-04-19 2023-12-26 马伦戈治疗公司 多特异性分子及其用途
JP7348899B2 (ja) 2017-12-08 2023-09-21 マレンゴ・セラピューティクス,インコーポレーテッド 多重特異性分子及びその使用
JP7463281B2 (ja) * 2018-03-05 2024-04-08 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド コロニー刺激因子を標的とすることによる、緑内障および視神経症のための療法
CN109053887B (zh) * 2018-07-18 2019-07-23 博奥信生物技术(南京)有限公司 一种抗人csf-1r单克隆抗体及用途
CN108948199B (zh) * 2018-07-18 2019-06-21 博奥信生物技术(南京)有限公司 抗人csf-1r单克隆抗体及其用途
EP3833762A4 (en) 2018-08-09 2022-09-28 Verseau Therapeutics, Inc. OLIGONUCLEOTIDE COMPOSITIONS FOR TARGETING CCR2 AND CSF1R AND THEIR USES
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CN112822999A (zh) * 2018-09-13 2021-05-18 豪夫迈·罗氏有限公司 Csf-1r抗体制剂
AU2019346645A1 (en) 2018-09-27 2021-04-29 Marengo Therapeutics, Inc. CSF1R/CCR2 multispecific antibodies
JP2022532837A (ja) * 2019-05-24 2022-07-20 エリクシロン・イミュノセラピューティクス・(ホンコン)・リミテッド 抗csf1r抗体、il10融合タンパク質、及びそれらの使用

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Also Published As

Publication number Publication date
MX2017008218A (es) 2017-10-18
ES2843586T3 (es) 2021-07-19
US10040858B2 (en) 2018-08-07
CA2969341C (en) 2023-07-04
EP3237447B1 (en) 2020-12-02
US20190119390A1 (en) 2019-04-25
BR112017013111A2 (pt) 2018-05-15
EA201791421A1 (ru) 2017-10-31
AU2015369854A1 (en) 2017-06-15
TW201630937A (zh) 2016-09-01
KR20170096187A (ko) 2017-08-23
CN107257806B (zh) 2021-08-10
AU2015369854B2 (en) 2021-07-01
JP2018501254A (ja) 2018-01-18
US10730949B2 (en) 2020-08-04
EP3237447A1 (en) 2017-11-01
CN107257806A (zh) 2017-10-17
SG11201704792UA (en) 2017-07-28
US20210009700A1 (en) 2021-01-14
WO2016106180A1 (en) 2016-06-30
US20160185869A1 (en) 2016-06-30
IL252716A0 (en) 2017-08-31
CA2969341A1 (en) 2016-06-30
JP6797801B2 (ja) 2020-12-09

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