BR112017013111A2 - métodos de tratamento de um distúrbio e de tratamento da sinovite, uso de um anticorpo e anticorpo - Google Patents

métodos de tratamento de um distúrbio e de tratamento da sinovite, uso de um anticorpo e anticorpo

Info

Publication number
BR112017013111A2
BR112017013111A2 BR112017013111A BR112017013111A BR112017013111A2 BR 112017013111 A2 BR112017013111 A2 BR 112017013111A2 BR 112017013111 A BR112017013111 A BR 112017013111A BR 112017013111 A BR112017013111 A BR 112017013111A BR 112017013111 A2 BR112017013111 A2 BR 112017013111A2
Authority
BR
Brazil
Prior art keywords
antibody
treating
methods
disorder
synovitis
Prior art date
Application number
BR112017013111A
Other languages
English (en)
Inventor
Hambleton Julie
Sankar Nilacantan
Sikorski Robert
Original Assignee
Five Prime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics Inc filed Critical Five Prime Therapeutics Inc
Publication of BR112017013111A2 publication Critical patent/BR112017013111A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

são fornecidos métodos de tratamento da sinovite vilonodular pigmentada (pvns) com anticorpos que se ligam ao receptor do fator estimulador de colônia 1 (csf1r).
BR112017013111A 2014-12-22 2015-12-21 métodos de tratamento de um distúrbio e de tratamento da sinovite, uso de um anticorpo e anticorpo BR112017013111A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462095297P 2014-12-22 2014-12-22
US201562163251P 2015-05-18 2015-05-18
PCT/US2015/067012 WO2016106180A1 (en) 2014-12-22 2015-12-21 Anti-csf1r antibodies for treating pvns

Publications (1)

Publication Number Publication Date
BR112017013111A2 true BR112017013111A2 (pt) 2018-05-15

Family

ID=55135539

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017013111A BR112017013111A2 (pt) 2014-12-22 2015-12-21 métodos de tratamento de um distúrbio e de tratamento da sinovite, uso de um anticorpo e anticorpo

Country Status (16)

Country Link
US (3) US10040858B2 (pt)
EP (1) EP3237447B1 (pt)
JP (1) JP6797801B2 (pt)
KR (1) KR20170096187A (pt)
CN (1) CN107257806B (pt)
AU (1) AU2015369854B2 (pt)
BR (1) BR112017013111A2 (pt)
CA (1) CA2969341C (pt)
EA (1) EA201791421A1 (pt)
ES (1) ES2843586T3 (pt)
HK (1) HK1245804A1 (pt)
IL (1) IL252716A0 (pt)
MX (1) MX2017008218A (pt)
SG (1) SG11201704792UA (pt)
TW (1) TW201630937A (pt)
WO (1) WO2016106180A1 (pt)

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RU2756236C2 (ru) 2016-06-20 2021-09-28 Кимаб Лимитед PD-L1 специфические антитела
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JP7463281B2 (ja) * 2018-03-05 2024-04-08 ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド コロニー刺激因子を標的とすることによる、緑内障および視神経症のための療法
CN109053887B (zh) * 2018-07-18 2019-07-23 博奥信生物技术（南京）有限公司 一种抗人csf-1r单克隆抗体及用途
CN108948199B (zh) * 2018-07-18 2019-06-21 博奥信生物技术（南京）有限公司 抗人csf-1r单克隆抗体及其用途
JP2021534101A (ja) 2018-08-09 2021-12-09 ヴェルソー セラピューティクス， インコーポレイテッド Ｃｃｒ２及びｃｓｆ１ｒを標的とするためのオリゴヌクレオチド組成物ならびにその使用
EP3836951A1 (en) 2018-08-13 2021-06-23 Signablok, Inc. Peptides and compositions for targeted treatment and imaging
CN112822999A (zh) * 2018-09-13 2021-05-18 豪夫迈·罗氏有限公司 Csf-1r抗体制剂
CN113164777A (zh) 2018-09-27 2021-07-23 马伦戈治疗公司 Csf1r/ccr2多特异性抗体
CN113811331A (zh) * 2019-05-24 2021-12-17 安立玺荣生医(香港)有限公司 抗csf1r抗体、il10融合蛋白及其用途

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Also Published As

Publication number Publication date
TW201630937A (zh) 2016-09-01
AU2015369854A1 (en) 2017-06-15
SG11201704792UA (en) 2017-07-28
CN107257806B (zh) 2021-08-10
IL252716A0 (en) 2017-08-31
EP3237447B1 (en) 2020-12-02
EP3237447A1 (en) 2017-11-01
ES2843586T3 (es) 2021-07-19
US10040858B2 (en) 2018-08-07
HK1245804A1 (zh) 2018-08-31
US20160185869A1 (en) 2016-06-30
US10730949B2 (en) 2020-08-04
MX2017008218A (es) 2017-10-18
US20190119390A1 (en) 2019-04-25
US20210009700A1 (en) 2021-01-14
WO2016106180A1 (en) 2016-06-30
CA2969341C (en) 2023-07-04
CA2969341A1 (en) 2016-06-30
AU2015369854B2 (en) 2021-07-01
EA201791421A1 (ru) 2017-10-31
CN107257806A (zh) 2017-10-17
JP2018501254A (ja) 2018-01-18
KR20170096187A (ko) 2017-08-23
JP6797801B2 (ja) 2020-12-09

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