HK1244805A1 - 一種新毒素及其中間體的製備方法 - Google Patents
一種新毒素及其中間體的製備方法Info
- Publication number
- HK1244805A1 HK1244805A1 HK18104330.1A HK18104330A HK1244805A1 HK 1244805 A1 HK1244805 A1 HK 1244805A1 HK 18104330 A HK18104330 A HK 18104330A HK 1244805 A1 HK1244805 A1 HK 1244805A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparing intermediate
- new toxin
- toxin
- new
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610107901 | 2016-02-26 | ||
PCT/CN2017/074756 WO2017144015A1 (zh) | 2016-02-26 | 2017-02-24 | 一种新毒素及其中间体的制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1244805A1 true HK1244805A1 (zh) | 2018-08-17 |
Family
ID=59685835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18104330.1A HK1244805A1 (zh) | 2016-02-26 | 2018-03-29 | 一種新毒素及其中間體的製備方法 |
Country Status (13)
Country | Link |
---|---|
US (1) | US10513510B2 (zh) |
EP (1) | EP3421463A4 (zh) |
JP (1) | JP2019510000A (zh) |
KR (1) | KR20180115743A (zh) |
CN (1) | CN107531680B (zh) |
AU (1) | AU2017223532A1 (zh) |
BR (1) | BR112018016983A2 (zh) |
CA (1) | CA3015098A1 (zh) |
HK (1) | HK1244805A1 (zh) |
MX (1) | MX2018010128A (zh) |
RU (1) | RU2018132749A (zh) |
TW (1) | TWI732826B (zh) |
WO (1) | WO2017144015A1 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201912626A (zh) * | 2017-09-04 | 2019-04-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種新毒素及其中間體的製備方法 |
CN112390853A (zh) * | 2019-08-11 | 2021-02-23 | 复旦大学 | 海兔毒素10类似物及其制备方法 |
CA3184724A1 (en) | 2020-07-27 | 2022-02-03 | Wenming REN | Anti-cd79b antibody-drug conjugate, and preparation method therefor and pharmaceutical use thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2861170B1 (fr) | 2003-10-16 | 2006-01-20 | Tijani Gharbi | Dispositif optique pour determiner au moins une caracteristique dimensionnelle d'une goutte de liquide |
CA2841741C (en) * | 2003-11-06 | 2020-01-07 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
NZ580115A (en) * | 2004-09-23 | 2010-10-29 | Genentech Inc | Cysteine engineered antibody light chains and conjugates |
TW200833328A (en) * | 2006-12-28 | 2008-08-16 | Actelion Pharmaceuticals Ltd | 2-aza-bicyclo[3.1.0]hexane derivatives |
TWI476190B (zh) * | 2009-03-30 | 2015-03-11 | 必治妥美雅史谷比公司 | C型肝炎病毒抑制劑 |
TWI582112B (zh) | 2011-04-21 | 2017-05-11 | 西雅圖遺傳學公司 | 新穎結合劑-藥物接合物(ADCs)及其用途(二) |
EP2780039B9 (en) | 2011-11-17 | 2018-08-22 | Pfizer Inc | Cytotoxic peptides and antibody drug conjugates thereof |
CA2859255A1 (en) | 2011-12-14 | 2013-06-20 | Seattle Genetics, Inc. | New antibody drug conjugates (adcs) and the use thereof |
FR3005051A1 (fr) * | 2013-04-25 | 2014-10-31 | Pf Medicament | Derives de la dolastatine 10 et d'auristatines |
EP3134125B1 (en) * | 2014-04-25 | 2019-10-09 | Pierre Fabre Medicament | Antibody-drug-conjugate and its use for the treatment of cancer |
WO2016127790A1 (zh) | 2015-02-15 | 2016-08-18 | 江苏恒瑞医药股份有限公司 | 配体-细胞毒性药物偶联物、其制备方法及其应用 |
CN106188293A (zh) * | 2015-04-17 | 2016-12-07 | 江苏恒瑞医药股份有限公司 | 抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途 |
-
2017
- 2017-02-24 TW TW106106404A patent/TWI732826B/zh active
- 2017-02-24 CN CN201780001254.7A patent/CN107531680B/zh active Active
- 2017-02-24 JP JP2018544080A patent/JP2019510000A/ja active Pending
- 2017-02-24 EP EP17755844.2A patent/EP3421463A4/en not_active Withdrawn
- 2017-02-24 US US16/078,396 patent/US10513510B2/en not_active Expired - Fee Related
- 2017-02-24 AU AU2017223532A patent/AU2017223532A1/en not_active Abandoned
- 2017-02-24 KR KR1020187026912A patent/KR20180115743A/ko unknown
- 2017-02-24 MX MX2018010128A patent/MX2018010128A/es unknown
- 2017-02-24 CA CA3015098A patent/CA3015098A1/en not_active Abandoned
- 2017-02-24 RU RU2018132749A patent/RU2018132749A/ru not_active Application Discontinuation
- 2017-02-24 BR BR112018016983-8A patent/BR112018016983A2/zh not_active IP Right Cessation
- 2017-02-24 WO PCT/CN2017/074756 patent/WO2017144015A1/zh active Application Filing
-
2018
- 2018-03-29 HK HK18104330.1A patent/HK1244805A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20190055223A1 (en) | 2019-02-21 |
CA3015098A1 (en) | 2017-08-31 |
TWI732826B (zh) | 2021-07-11 |
CN107531680B (zh) | 2020-09-11 |
MX2018010128A (es) | 2019-01-21 |
US10513510B2 (en) | 2019-12-24 |
RU2018132749A (ru) | 2020-03-26 |
JP2019510000A (ja) | 2019-04-11 |
KR20180115743A (ko) | 2018-10-23 |
WO2017144015A1 (zh) | 2017-08-31 |
TW201730185A (zh) | 2017-09-01 |
EP3421463A1 (en) | 2019-01-02 |
EP3421463A4 (en) | 2019-10-23 |
AU2017223532A1 (en) | 2018-08-30 |
CN107531680A (zh) | 2018-01-02 |
BR112018016983A2 (zh) | 2018-12-26 |
RU2018132749A3 (zh) | 2020-04-14 |
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