HK1223404A1 - 用於在核酸測定中改善熔鏈分辨和多重性的探針 - Google Patents
用於在核酸測定中改善熔鏈分辨和多重性的探針Info
- Publication number
- HK1223404A1 HK1223404A1 HK16111674.2A HK16111674A HK1223404A1 HK 1223404 A1 HK1223404 A1 HK 1223404A1 HK 16111674 A HK16111674 A HK 16111674A HK 1223404 A1 HK1223404 A1 HK 1223404A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- multiplexing
- probes
- nucleic acid
- acid assays
- improved melt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/301—Hairpin oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/107—Temperature of melting, i.e. Tm
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361864128P | 2013-08-09 | 2013-08-09 | |
| PCT/US2014/050514 WO2015021460A1 (en) | 2013-08-09 | 2014-08-11 | Probes for improved melt discrimination and multiplexing in nucleic acid assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1223404A1 true HK1223404A1 (zh) | 2017-07-28 |
Family
ID=52448967
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16111674.2A HK1223404A1 (zh) | 2013-08-09 | 2016-10-09 | 用於在核酸測定中改善熔鏈分辨和多重性的探針 |
| HK18105761.6A HK1246363A1 (zh) | 2013-08-09 | 2018-05-04 | 用於在核酸測定中改善熔鏈分辨和多重性的探針 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18105761.6A HK1246363A1 (zh) | 2013-08-09 | 2018-05-04 | 用於在核酸測定中改善熔鏈分辨和多重性的探針 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9657332B2 (zh) |
| EP (4) | EP4321867A3 (zh) |
| KR (3) | KR102398399B1 (zh) |
| CN (3) | CN105555971B (zh) |
| HK (2) | HK1223404A1 (zh) |
| WO (1) | WO2015021460A1 (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140066782A (ko) * | 2011-09-29 | 2014-06-02 | 루미넥스 코포레이션 | 가수분해 프로브 |
| KR102398399B1 (ko) * | 2013-08-09 | 2022-05-16 | 루미넥스 코포레이션 | 핵산 에세이에서의 향상된 용융 식별 및 복합화를 위한 프로브 |
| CA2956812C (en) | 2014-08-11 | 2023-04-11 | Luminex Corporation | Probes for improved melt discrimination and multiplexing in nucleic acid assays |
| JP6740242B2 (ja) * | 2014-12-15 | 2020-08-12 | ルミネックス コーポレーション | 詳細検定プロトコル仕様 |
| CN108467889A (zh) * | 2018-04-04 | 2018-08-31 | 苏州创澜生物科技有限公司 | 一种用于多重pcr的荧光探针及其应用 |
| CA3108430A1 (en) | 2018-08-09 | 2020-02-13 | Speedx Pty Ltd | Multiplex detection of nucleic acids |
| US11371080B2 (en) | 2018-11-30 | 2022-06-28 | Luminex Corporation | Methods and probes for performing PCR with melt analysis for increased multiplexing |
| US20230002805A1 (en) * | 2021-06-25 | 2023-01-05 | Enzo Biochem, Inc. | Use of organic cationic compounds to accelerate nucleic acid hybridization, synthesis, and amplification |
| KR20240058112A (ko) * | 2021-09-17 | 2024-05-03 | 주식회사 씨젠 | 합성 비자연 염기를 포함하는 태그 올리고뉴클레오타이드를 이용한 타겟 핵산 서열의 검출 |
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| KR102398399B1 (ko) * | 2013-08-09 | 2022-05-16 | 루미넥스 코포레이션 | 핵산 에세이에서의 향상된 용융 식별 및 복합화를 위한 프로브 |
| CA2956812C (en) * | 2014-08-11 | 2023-04-11 | Luminex Corporation | Probes for improved melt discrimination and multiplexing in nucleic acid assays |
-
2014
- 2014-08-11 KR KR1020217017550A patent/KR102398399B1/ko active IP Right Grant
- 2014-08-11 CN CN201480051337.3A patent/CN105555971B/zh active Active
- 2014-08-11 US US14/456,239 patent/US9657332B2/en active Active
- 2014-08-11 WO PCT/US2014/050514 patent/WO2015021460A1/en active Application Filing
- 2014-08-11 CN CN201710604440.1A patent/CN107435067B/zh active Active
- 2014-08-11 CN CN202110663287.6A patent/CN113528621A/zh active Pending
- 2014-08-11 EP EP23202275.6A patent/EP4321867A3/en active Pending
- 2014-08-11 KR KR1020207018426A patent/KR102265313B1/ko active IP Right Grant
- 2014-08-11 KR KR1020167006257A patent/KR102129506B1/ko active Application Filing
- 2014-08-11 EP EP20171628.9A patent/EP3715470B1/en active Active
- 2014-08-11 EP EP18187333.2A patent/EP3461913B1/en active Active
- 2014-08-11 EP EP14834166.2A patent/EP3030680B1/en active Active
-
2016
- 2016-10-09 HK HK16111674.2A patent/HK1223404A1/zh unknown
-
2017
- 2017-04-28 US US15/581,067 patent/US10612074B2/en active Active
-
2018
- 2018-05-04 HK HK18105761.6A patent/HK1246363A1/zh unknown
-
2020
- 2020-02-28 US US16/804,060 patent/US11261481B2/en active Active
-
2022
- 2022-01-31 US US17/588,719 patent/US20220154257A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HK1246363A1 (zh) | 2018-09-07 |
| US9657332B2 (en) | 2017-05-23 |
| EP3461913B1 (en) | 2020-06-24 |
| CN107435067A (zh) | 2017-12-05 |
| EP3461913A1 (en) | 2019-04-03 |
| US10612074B2 (en) | 2020-04-07 |
| KR102129506B1 (ko) | 2020-07-06 |
| EP3030680B1 (en) | 2018-10-03 |
| KR20210072138A (ko) | 2021-06-16 |
| EP3030680A4 (en) | 2017-04-19 |
| US11261481B2 (en) | 2022-03-01 |
| US20200199658A1 (en) | 2020-06-25 |
| US20150044680A1 (en) | 2015-02-12 |
| CN105555971B (zh) | 2017-08-29 |
| KR102398399B1 (ko) | 2022-05-16 |
| EP3030680A1 (en) | 2016-06-15 |
| US20170298423A1 (en) | 2017-10-19 |
| EP4321867A3 (en) | 2024-05-15 |
| US20220154257A1 (en) | 2022-05-19 |
| CN105555971A (zh) | 2016-05-04 |
| EP3715470A1 (en) | 2020-09-30 |
| KR20200078715A (ko) | 2020-07-01 |
| EP4321867A2 (en) | 2024-02-14 |
| KR102265313B1 (ko) | 2021-06-15 |
| WO2015021460A1 (en) | 2015-02-12 |
| KR20160033239A (ko) | 2016-03-25 |
| CN107435067B (zh) | 2021-07-09 |
| EP3715470B1 (en) | 2023-10-11 |
| CN113528621A (zh) | 2021-10-22 |
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