HK1221977A1 - 用於產生供生產重組蛋白的哺乳動物生產細胞的物品和方法 - Google Patents

用於產生供生產重組蛋白的哺乳動物生產細胞的物品和方法

Info

Publication number
HK1221977A1
HK1221977A1 HK16110195.4A HK16110195A HK1221977A1 HK 1221977 A1 HK1221977 A1 HK 1221977A1 HK 16110195 A HK16110195 A HK 16110195A HK 1221977 A1 HK1221977 A1 HK 1221977A1
Authority
HK
Hong Kong
Prior art keywords
generation
production
methods
recombinant proteins
producer cells
Prior art date
Application number
HK16110195.4A
Other languages
English (en)
Inventor
.費爾
.朗斯
.揚
.塞耶
.斯梅爾斯
Original Assignee
Lonza Biologics Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Biologics Plc filed Critical Lonza Biologics Plc
Publication of HK1221977A1 publication Critical patent/HK1221977A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • C12N2310/141MicroRNAs, miRNAs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00Production
    • C12N2330/50Biochemical production, i.e. in a transformed host cell
    • C12N2330/51Specially adapted vectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK16110195.4A 2013-08-06 2016-08-26 用於產生供生產重組蛋白的哺乳動物生產細胞的物品和方法 HK1221977A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13179342 2013-08-06
PCT/EP2014/066352 WO2015018703A1 (en) 2013-08-06 2014-07-30 Means and methods for the generation of mammalian producer cells for the production of recombinant proteins

Publications (1)

Publication Number Publication Date
HK1221977A1 true HK1221977A1 (zh) 2017-06-16

Family

ID=48914165

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110195.4A HK1221977A1 (zh) 2013-08-06 2016-08-26 用於產生供生產重組蛋白的哺乳動物生產細胞的物品和方法

Country Status (9)

Country Link
US (1) US10669541B2 (zh)
EP (1) EP3030656B1 (zh)
JP (1) JP6676526B2 (zh)
CN (1) CN105849265B (zh)
ES (1) ES2698610T3 (zh)
HK (1) HK1221977A1 (zh)
SG (1) SG11201600872UA (zh)
TW (1) TWI646194B (zh)
WO (1) WO2015018703A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020507331A (ja) 2017-02-17 2020-03-12 ロンザ リミテッドLonza Limited アデノ随伴ウイルスを生産するための哺乳動物細胞
CN111372946A (zh) 2017-02-17 2020-07-03 隆萨有限公司 难以表达的蛋白质的多位点特异性整合细胞

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009545309A (ja) * 2006-08-04 2009-12-24 ダブリン シティ ユニバーシティ 組換え型生物学的製剤を製造する方法
EP3075396A1 (en) * 2010-10-17 2016-10-05 Yeda Research and Development Co. Ltd. Methods and compositions for the treatment of insulin-associated medical conditions
CN102784398B (zh) * 2011-05-16 2014-06-18 南京大学 内皮抑素作为递送***和化学合成的rna干扰分子组成的组合物及应用

Also Published As

Publication number Publication date
CN105849265A (zh) 2016-08-10
WO2015018703A1 (en) 2015-02-12
TW201522631A (zh) 2015-06-16
EP3030656A1 (en) 2016-06-15
US10669541B2 (en) 2020-06-02
EP3030656B1 (en) 2018-08-22
ES2698610T3 (es) 2019-02-05
TWI646194B (zh) 2019-01-01
JP2016532445A (ja) 2016-10-20
US20160177300A1 (en) 2016-06-23
CN105849265B (zh) 2021-03-26
SG11201600872UA (en) 2016-03-30
JP6676526B2 (ja) 2020-04-08

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