US6696561B1
(en)
|
1909-07-09 |
2004-02-24 |
Basf Aktiengesellschaft |
Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
|
US4475196A
(en)
|
1981-03-06 |
1984-10-02 |
Zor Clair G |
Instrument for locating faults in aircraft passenger reading light and attendant call control system
|
US4447233A
(en)
|
1981-04-10 |
1984-05-08 |
Parker-Hannifin Corporation |
Medication infusion pump
|
US4439196A
(en)
|
1982-03-18 |
1984-03-27 |
Merck & Co., Inc. |
Osmotic drug delivery system
|
US4447224A
(en)
|
1982-09-20 |
1984-05-08 |
Infusaid Corporation |
Variable flow implantable infusion apparatus
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
US4486194A
(en)
|
1983-06-08 |
1984-12-04 |
James Ferrara |
Therapeutic device for administering medicaments through the skin
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
AU634186B2
(en)
|
1988-11-11 |
1993-02-18 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
US5800992A
(en)
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
US6040138A
(en)
|
1995-09-15 |
2000-03-21 |
Affymetrix, Inc. |
Expression monitoring by hybridization to high density oligonucleotide arrays
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5840867A
(en)
|
1991-02-21 |
1998-11-24 |
Gilead Sciences, Inc. |
Aptamer analogs specific for biomolecules
|
US5582981A
(en)
|
1991-08-14 |
1996-12-10 |
Gilead Sciences, Inc. |
Method for identifying an oligonucleotide aptamer specific for a target
|
WO1993009668A1
(en)
|
1991-11-22 |
1993-05-27 |
Affymax Technology N.V. |
Combinatorial strategies for polymer synthesis
|
AU665221B2
(en)
|
1991-12-02 |
1995-12-21 |
Cambridge Antibody Technology Limited |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
ES2227512T3
(es)
|
1991-12-02 |
2005-04-01 |
Medical Research Council |
Produccion de anticuerpos contra auto-antigenos a partir de repertorios de segmentos de anticuerpos fijados en un fago.
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5756291A
(en)
|
1992-08-21 |
1998-05-26 |
Gilead Sciences, Inc. |
Aptamers specific for biomolecules and methods of making
|
US6765087B1
(en)
|
1992-08-21 |
2004-07-20 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
DK1087013T3
(da)
|
1992-08-21 |
2009-05-11 |
Univ Bruxelles |
Immunoglobuliner uden lette kæder
|
DK0698097T3
(da)
|
1993-04-29 |
2001-10-08 |
Unilever Nv |
Produktion af antistoffer eller (funktionaliserede) fragmenter deraf afledt af Camelidae-immunoglobuliner med tung kæde
|
SE9400088D0
(sv)
|
1994-01-14 |
1994-01-14 |
Kabi Pharmacia Ab |
Bacterial receptor structures
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
US6111095A
(en)
|
1995-06-07 |
2000-08-29 |
Merck & Co., Inc. |
Capped synthetic RNA, analogs, and aptamers
|
US5545531A
(en)
|
1995-06-07 |
1996-08-13 |
Affymax Technologies N.V. |
Methods for making a device for concurrently processing multiple biological chip assays
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
EP0880598A4
(en)
|
1996-01-23 |
2005-02-23 |
Affymetrix Inc |
RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
|
US5792613A
(en)
|
1996-06-12 |
1998-08-11 |
The Curators Of The University Of Missouri |
Method for obtaining RNA aptamers based on shape selection
|
US6261804B1
(en)
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
ATE332368T1
(de)
|
1997-01-21 |
2006-07-15 |
Gen Hospital Corp |
Selektion von proteinen mittels rns-protein fusionen
|
DE19742706B4
(de)
|
1997-09-26 |
2013-07-25 |
Pieris Proteolab Ag |
Lipocalinmuteine
|
GB9722131D0
(en)
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
DE69829402T2
(de)
|
1997-10-31 |
2006-04-13 |
Affymetrix, Inc. (a Delaware Corp.), Santa Clara |
Expressionsprofile in adulten und fötalen organen
|
US6261783B1
(en)
|
1997-12-15 |
2001-07-17 |
Gilead Sciences, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US6020135A
(en)
|
1998-03-27 |
2000-02-01 |
Affymetrix, Inc. |
P53-regulated genes
|
US6458559B1
(en)
|
1998-04-22 |
2002-10-01 |
Cornell Research Foundation, Inc. |
Multivalent RNA aptamers and their expression in multicellular organisms
|
US7115396B2
(en)
|
1998-12-10 |
2006-10-03 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
US6818418B1
(en)
|
1998-12-10 |
2004-11-16 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
US7595383B1
(en)
|
1999-05-04 |
2009-09-29 |
University Of Medicine And Dentistry Of New Jersey |
Secreted proteins of Mycobacterium tuberculosis and their use as vaccines and diagnostic reagents
|
CA2382146A1
(en)
*
|
1999-08-20 |
2001-03-01 |
Human Genome Sciences, Inc. |
Pgrp-l polynucleotides, polypeptides, and antibodies
|
ATE448301T1
(de)
|
2000-09-08 |
2009-11-15 |
Univ Zuerich |
Sammlung von proteinen mit sich wiederholenden sequenzen (repeat proteins), die repetitive sequenzmodule enthalten
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US20060223114A1
(en)
|
2001-04-26 |
2006-10-05 |
Avidia Research Institute |
Protein scaffolds and uses thereof
|
US20030157561A1
(en)
|
2001-11-19 |
2003-08-21 |
Kolkman Joost A. |
Combinatorial libraries of monomer domains
|
WO2002088171A2
(en)
|
2001-04-26 |
2002-11-07 |
Avidia Research Institute |
Combinatorial libraries of monomer domains
|
US20040175756A1
(en)
|
2001-04-26 |
2004-09-09 |
Avidia Research Institute |
Methods for using combinatorial libraries of monomer domains
|
US20050048512A1
(en)
|
2001-04-26 |
2005-03-03 |
Avidia Research Institute |
Combinatorial libraries of monomer domains
|
US20050053973A1
(en)
|
2001-04-26 |
2005-03-10 |
Avidia Research Institute |
Novel proteins with targeted binding
|
US20050089932A1
(en)
|
2001-04-26 |
2005-04-28 |
Avidia Research Institute |
Novel proteins with targeted binding
|
EP1399484B1
(en)
|
2001-06-28 |
2010-08-11 |
Domantis Limited |
Dual-specific ligand and its use
|
WO2004003019A2
(en)
|
2002-06-28 |
2004-01-08 |
Domantis Limited |
Immunoglobin single variant antigen-binding domains and dual-specific constructs
|
US6872541B2
(en)
*
|
2001-07-25 |
2005-03-29 |
Coulter International Corp. |
Method and compositions for analysis of pentraxin receptors as indicators of disease
|
JP2006523090A
(ja)
|
2002-12-27 |
2006-10-12 |
ドマンティス リミテッド |
リガンドに、そしてリガンド受容体に特異的な二重特異性単一ドメイン抗体
|
EP1627062A1
(en)
|
2003-05-14 |
2006-02-22 |
Domantis Limited |
A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire
|
PL1639011T3
(pl)
|
2003-06-30 |
2009-05-29 |
Domantis Ltd |
Pegilowane przeciwciała jednodomenowe (dAb)
|
CA2543360A1
(en)
|
2003-10-24 |
2005-05-06 |
Joost A. Kolkman |
Ldl receptor class a and egf domain monomers and multimers
|
US20060008844A1
(en)
|
2004-06-17 |
2006-01-12 |
Avidia Research Institute |
c-Met kinase binding proteins
|
GB0421639D0
(en)
*
|
2004-09-29 |
2004-10-27 |
Proteome Sciences Plc |
Methods and compositions relating to alzheimer's disease
|
MX2007005884A
(es)
|
2004-11-16 |
2008-02-12 |
Amgen Mountain View Inc |
Andamios de proteina y usos de los mismos.
|
AU2005325801A1
(en)
|
2005-01-31 |
2006-08-03 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
GB0510511D0
(en)
|
2005-05-23 |
2005-06-29 |
St Georges Entpr Ltd |
Diagnosis of tuberculosis
|
EP1929073A4
(en)
|
2005-09-27 |
2010-03-10 |
Amunix Inc |
PROTEIN MEDICAMENT AND ITS USE
|
WO2007059782A1
(en)
|
2005-11-28 |
2007-05-31 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
US10611818B2
(en)
|
2007-09-27 |
2020-04-07 |
Agilent Technologies, Inc. |
MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
|
EP2065707A1
(en)
*
|
2007-11-28 |
2009-06-03 |
Laboratorios S.A.L.V.A.T., S.A. |
Detection of endometrial secretion markers for assesment of endometriosis
|
US20110129817A1
(en)
|
2009-11-30 |
2011-06-02 |
Baylor Research Institute |
Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
|
AP2011005546A0
(en)
|
2008-06-25 |
2011-02-28 |
Baylor Res Intitute |
Blood transcriptional signature of mycobacterium tuberculosis infection.
|
MX2011000655A
(es)
*
|
2008-07-18 |
2011-03-21 |
Oragenics Inc |
Composiciones para la deteccion y tratamiento de cancer colorrectal.
|
EP2536405A1
(en)
*
|
2010-02-16 |
2012-12-26 |
Universita Degli Studi di Siena |
Non peptidic 14-3-3 inhibitors and the use thereof
|
US20130045889A1
(en)
*
|
2010-04-13 |
2013-02-21 |
Pronota N.V. |
Biomarkers for hypertensive disorders of pregnancy
|
RU2447445C1
(ru)
*
|
2010-12-09 |
2012-04-10 |
Учреждение Российской академии медицинских наук Центральный научно-исследовательский институт туберкулеза РАМН |
Способ оценки эффективности лечения и динамики деструктивных изменений в легочной ткани при туберкулезе легких
|
WO2012085652A2
(en)
*
|
2010-12-23 |
2012-06-28 |
Centre Hospitalier Universitaire Vaudois |
Methods for differentiating between disease states
|
WO2012115885A1
(en)
|
2011-02-22 |
2012-08-30 |
Caris Life Sciences Luxembourg Holdings, S.A.R.L. |
Circulating biomarkers
|
JP6776582B2
(ja)
|
2016-03-31 |
2020-10-28 |
Tdk株式会社 |
電子部品
|