HK1217171A1 - 用於治療相移睡眠障礙的 拮抗劑 - Google Patents

用於治療相移睡眠障礙的 拮抗劑

Info

Publication number
HK1217171A1
HK1217171A1 HK16105157.0A HK16105157A HK1217171A1 HK 1217171 A1 HK1217171 A1 HK 1217171A1 HK 16105157 A HK16105157 A HK 16105157A HK 1217171 A1 HK1217171 A1 HK 1217171A1
Authority
HK
Hong Kong
Prior art keywords
antagonists
phase shift
sleep disorders
shift sleep
treat phase
Prior art date
Application number
HK16105157.0A
Other languages
English (en)
Inventor
帕特里克‧施耐德
克里斯托夫‧格倫德紹博
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1217171A1 publication Critical patent/HK1217171A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dermatology (AREA)
HK16105157.0A 2013-08-19 2016-05-05 用於治療相移睡眠障礙的 拮抗劑 HK1217171A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13180836 2013-08-19
PCT/EP2014/067264 WO2015024819A1 (en) 2013-08-19 2014-08-12 V1a antagonists to treat phase shift sleep disorders

Publications (1)

Publication Number Publication Date
HK1217171A1 true HK1217171A1 (zh) 2016-12-30

Family

ID=48985673

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105157.0A HK1217171A1 (zh) 2013-08-19 2016-05-05 用於治療相移睡眠障礙的 拮抗劑

Country Status (21)

Country Link
US (1) US10265327B2 (zh)
EP (1) EP3035939B1 (zh)
JP (1) JP6427192B2 (zh)
KR (1) KR20160042903A (zh)
CN (1) CN105492010B (zh)
AU (1) AU2014310733A1 (zh)
BR (1) BR112016001948A2 (zh)
CA (1) CA2919738A1 (zh)
CL (1) CL2016000325A1 (zh)
CR (1) CR20160042A (zh)
EA (1) EA201690179A1 (zh)
ES (1) ES2793929T3 (zh)
HK (1) HK1217171A1 (zh)
IL (1) IL243387A0 (zh)
MA (1) MA38867A1 (zh)
MX (1) MX2016001940A (zh)
PE (1) PE20160203A1 (zh)
PH (1) PH12016500124A1 (zh)
PL (1) PL3035939T3 (zh)
SG (1) SG11201600991QA (zh)
WO (1) WO2015024819A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6454707B2 (ja) 2013-12-05 2019-01-16 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft trans−8−クロロ−5−メチル−1−[4−(ピリジン−2−イルオキシ)−シクロヘキシル]−5,6−ジヒドロ−4H−2,3,5,10b−テトラアザ−ベンゾ[e]アズレン及びその結晶形態の合成
WO2017191117A1 (en) 2016-05-03 2017-11-09 Bayer Pharma Aktiengesellschaft V1a receptor antagonists for use in the treatment of renal diseases
WO2018133835A1 (en) * 2017-01-20 2018-07-26 National Institute Of Biological Sciences, Beijing Nucleoside analogue regulating mammalian circadian rhythm
KR20200097702A (ko) * 2017-12-08 2020-08-19 에프. 호프만-라 로슈 아게 약학 제형
EP4185570A1 (en) * 2020-07-23 2023-05-31 F. Hoffmann-La Roche AG Cyclohexyl substituted triazoles as vasopressin receptor v1 a antagonists
JP2023534721A (ja) * 2020-07-23 2023-08-10 エフ. ホフマン-ラ ロシュ アーゲー バソプレシン受容体v1aアンタゴニストとしてのヘテロアリール-メチル置換トリアゾール

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1330451B1 (en) * 2000-10-27 2008-01-23 Ortho-McNeil Pharmaceutical, Inc. Substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide y modulators
US20050107411A1 (en) * 2001-12-17 2005-05-19 Macneil Douglas J. Method for treating circadian rhythm disruptions
GB0303852D0 (en) * 2003-02-19 2003-03-26 Pfizer Ltd Triazole compounds useful in therapy
MX2007002248A (es) * 2004-08-25 2008-10-02 Pfizer Triazolobenzodiazepinas y su uso como antagonistas de vasopresina.
ES2431279T3 (es) * 2008-11-28 2013-11-25 F. Hoffmann-La Roche Ag Arilciclohexiléteres de dihidro-tetraazabenzoazulenos para uso como antagonistas del receptor V1A de la vasopresina
JPWO2013176220A1 (ja) * 2012-05-25 2016-01-14 国立大学法人京都大学 概日リズム調整

Also Published As

Publication number Publication date
EP3035939A1 (en) 2016-06-29
JP6427192B2 (ja) 2018-11-21
SG11201600991QA (en) 2016-03-30
US20180064727A1 (en) 2018-03-08
ES2793929T3 (es) 2020-11-17
CL2016000325A1 (es) 2016-09-30
IL243387A0 (en) 2016-02-29
EP3035939B1 (en) 2020-03-25
MA38867A1 (fr) 2018-01-31
CA2919738A1 (en) 2015-02-26
MX2016001940A (es) 2016-06-02
AU2014310733A1 (en) 2016-02-04
KR20160042903A (ko) 2016-04-20
US10265327B2 (en) 2019-04-23
PH12016500124A1 (en) 2016-04-25
CN105492010B (zh) 2020-01-03
EA201690179A1 (ru) 2016-06-30
BR112016001948A2 (pt) 2017-08-01
PE20160203A1 (es) 2016-04-20
WO2015024819A1 (en) 2015-02-26
JP2016528266A (ja) 2016-09-15
PL3035939T3 (pl) 2020-07-27
CN105492010A (zh) 2016-04-13
CR20160042A (es) 2016-04-01

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