HK1216641A1 - 用於治療σ受體相關疾病和病症的 -***- -胺 - Google Patents

用於治療σ受體相關疾病和病症的 -***- -胺

Info

Publication number: HK1216641A1
Authority: HK; Hong Kong
Prior art keywords: triazole; disorders; treatment; related diseases; amine derivatives
Prior art date: 2013-01-07

Application number

HK16104496.3A

Other languages

English (en)

Inventor

Antoni Torrens-Jover

Ute Christmann

Jos-Luis Diaz-Fernandez

Carmen Almansa-Rosales

Original Assignee

Esteve Labor Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-01-07

Filing date

2016-04-19

Publication date

2016-11-25

2016-04-19 Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr

2016-11-25 Publication of HK1216641A1 publication Critical patent/HK1216641A1/zh

Links

JSIAIROWMJGMQZ-UHFFFAOYSA-N 2h-triazol-4-amine Chemical class NC1=CNN=N1 JSIAIROWMJGMQZ-UHFFFAOYSA-N 0.000 title 1
208000037765 diseases and disorders Diseases 0.000 title 1
108010085082 sigma receptors Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Transplantation (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

HK16104496.3A 2013-01-07 2016-04-19 用於治療σ受體相關疾病和病症的 -***- -胺 HK1216641A1 (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP13382002.7A EP2752411A1 (en)	2013-01-07	2013-01-07	1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders
PCT/EP2014/000012 WO2014106622A1 (en)	2013-01-07	2014-01-07	1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders

Publications (1)

Publication Number	Publication Date
HK1216641A1 true HK1216641A1 (zh)	2016-11-25

Family

ID=47603514

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK16104496.3A HK1216641A1 (zh)	2013-01-07	2016-04-19	用於治療σ受體相關疾病和病症的 -***- -胺

Country Status (10)

Country	Link
US (1)	US9611229B2 (zh)
EP (2)	EP2752411A1 (zh)
JP (1)	JP6370803B2 (zh)
CN (1)	CN104903309B (zh)
CA (1)	CA2893472A1 (zh)
ES (1)	ES2642403T3 (zh)
HK (1)	HK1216641A1 (zh)
MX (1)	MX2015008733A (zh)
PT (1)	PT2941424T (zh)
WO (1)	WO2014106622A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN107406420B (zh) *	2015-01-30	2020-11-06	纽罗克里生物科学有限公司	取代的***及与其相关的方法
WO2017121645A1 (en) *	2016-01-15	2017-07-20	Laboratorios Del Dr. Esteve, S.A.	3-ethyl-3-phenylazepane derivatives having multimodal activity against pain
CN106117154B (zh) *	2016-06-30	2018-12-14	昆明理工大学	一种邻芳氧基-1,4-二芳基-1,2,3-三氮唑衍生物及其制备方法和应用
KR20180036318A (ko) *	2016-09-30	2018-04-09	경북대학교 산학협력단	2-아미노-2-(1-도데실-1h-1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체를 유효성분으로 포함하는 퇴행성 신경질환 및 우울증 예방 또는 치료용 약학적 조성물
CN112386679B (zh) *	2020-11-18	2023-05-30	徐州医科大学	一种包载sigma-1受体的外泌体在制备抗抑郁药物中的应用
WO2024105225A1 (en)	2022-11-18	2024-05-23	Universitat De Barcelona	Synergistic combinations of a sigma receptor 1 (s1r) antagonist and a soluble epoxide hydrolase inhibitor (sehi) and their use in the treatment of pain

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002036119A1 (en) *	2000-11-02	2002-05-10	K And K Biosciences, Inc.	Δ2,-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke
EP1634873A1 (en)	2004-08-27	2006-03-15	Laboratorios Del Dr. Esteve, S.A.	Sigma receptor inhibitors
EP1829869A1 (en)	2006-03-02	2007-09-05	Laboratorios Del Dr. Esteve, S.A.	4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands
EP1829867A1 (en) *	2006-03-03	2007-09-05	Laboratorios Del Dr. Esteve, S.A.	Imidazole compounds having pharmaceutical activity towards the sigma receptor
EP1847542A1 (en)	2006-04-21	2007-10-24	Laboratorios del Dr. Esteve S.A.	Spiro[benzopyran] or spiro[benzofuran] derivatives which inhibit the sigma receptor
EP1921073A1 (en)	2006-11-10	2008-05-14	Laboratorios del Dr. Esteve S.A.	1,2,4-Triazole derivatives as sigma receptor inhibitors
EP1921071A1 (en)	2006-11-10	2008-05-14	Laboratorios del Dr. Esteve S.A.	1,2,3- triazole derivatives as sigma receptor inhibitors
EP2070933A1 (en)	2007-12-07	2009-06-17	Laboratorios del Dr. Esteve S.A.	Tricyclic triazolic compounds

2013
- 2013-01-07 EP EP13382002.7A patent/EP2752411A1/en not_active Withdrawn
2014
- 2014-01-07 US US14/759,280 patent/US9611229B2/en active Active
- 2014-01-07 CN CN201480004201.7A patent/CN104903309B/zh not_active Expired - Fee Related
- 2014-01-07 JP JP2015551174A patent/JP6370803B2/ja not_active Expired - Fee Related
- 2014-01-07 WO PCT/EP2014/000012 patent/WO2014106622A1/en active Application Filing
- 2014-01-07 CA CA2893472A patent/CA2893472A1/en not_active Abandoned
- 2014-01-07 PT PT147004303T patent/PT2941424T/pt unknown
- 2014-01-07 ES ES14700430.3T patent/ES2642403T3/es active Active
- 2014-01-07 MX MX2015008733A patent/MX2015008733A/es unknown
- 2014-01-07 EP EP14700430.3A patent/EP2941424B1/en not_active Not-in-force
2016
- 2016-04-19 HK HK16104496.3A patent/HK1216641A1/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT2941424T (pt)	2017-10-09
EP2941424B1 (en)	2017-07-05
US20150353510A1 (en)	2015-12-10
CA2893472A1 (en)	2014-07-10
WO2014106622A1 (en)	2014-07-10
US9611229B2 (en)	2017-04-04
ES2642403T3 (es)	2017-11-16
MX2015008733A (es)	2015-11-16
JP2016506415A (ja)	2016-03-03
EP2752411A1 (en)	2014-07-09
JP6370803B2 (ja)	2018-08-08
EP2941424A1 (en)	2015-11-11
CN104903309B (zh)	2017-12-19
CN104903309A (zh)	2015-09-09

Legal Events

Date	Code	Title	Description
2022-07-29	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20220104

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