HK1189887A1 - Method for industrially preparing nitrogen substituted amino-5,6,7,8- tetrahydronaphthol 5678- - Google Patents
Method for industrially preparing nitrogen substituted amino-5,6,7,8- tetrahydronaphthol 5678-Info
- Publication number
- HK1189887A1 HK1189887A1 HK14103006.0A HK14103006A HK1189887A1 HK 1189887 A1 HK1189887 A1 HK 1189887A1 HK 14103006 A HK14103006 A HK 14103006A HK 1189887 A1 HK1189887 A1 HK 1189887A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tetrahydronaphthol
- substituted amino
- nitrogen substituted
- preparing nitrogen
- industrially preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110179616 | 2011-06-27 | ||
PCT/CN2012/000863 WO2013000273A1 (en) | 2011-06-27 | 2012-06-21 | Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1189887A1 true HK1189887A1 (en) | 2014-06-20 |
Family
ID=47423417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14103006.0A HK1189887A1 (en) | 2011-06-27 | 2014-03-27 | Method for industrially preparing nitrogen substituted amino-5,6,7,8- tetrahydronaphthol 5678- |
Country Status (13)
Country | Link |
---|---|
US (1) | US8809590B2 (es) |
EP (1) | EP2723727B1 (es) |
JP (1) | JP5643467B2 (es) |
KR (1) | KR101478597B1 (es) |
CN (1) | CN103649071B (es) |
AU (1) | AU2012276179B2 (es) |
BR (1) | BR112013033559A2 (es) |
CA (1) | CA2839366C (es) |
ES (1) | ES2626024T3 (es) |
HK (1) | HK1189887A1 (es) |
PL (1) | PL2723727T3 (es) |
RU (1) | RU2558145C1 (es) |
WO (1) | WO2013000273A1 (es) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2752659A1 (de) * | 1976-12-07 | 1978-06-08 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
EP0026848B1 (de) * | 1979-09-14 | 1983-05-04 | Sandoz Ag | Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten |
JPS60258146A (ja) * | 1984-06-01 | 1985-12-20 | ウイットバイ リサーチ インコーポレイテッド | 置換2−アミノテトラリン類及び合成方法 |
US5382596A (en) | 1993-08-05 | 1995-01-17 | Whitby Research, Inc. | Substituted 2-aminotetralins |
CN1185225C (zh) | 1999-11-23 | 2005-01-19 | 阿德里斯制药公司 | 制备氮取代的氨基1,2,3,4-四氢化萘的改进方法 |
CA2735101C (en) * | 2008-10-13 | 2015-09-29 | Interquim, S.A. | Process for the preparation of optically active (s)-(-)-2-(n-propylamino)-5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds |
US8513438B2 (en) * | 2008-12-09 | 2013-08-20 | Interquim, S.A. | Process for the preparation of (6S)-(-)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (Rotigotine) |
CN102010400B (zh) * | 2009-09-07 | 2015-02-04 | 药源药物化学(上海)有限公司 | S-5-取代-n-2'-(噻吩-2-基-)乙基-1,2,3,4-四氢萘-2-胺或其手性酸盐和用于制备罗替戈汀 |
-
2012
- 2012-06-21 CA CA2839366A patent/CA2839366C/en not_active Expired - Fee Related
- 2012-06-21 US US14/128,131 patent/US8809590B2/en not_active Expired - Fee Related
- 2012-06-21 JP JP2014517396A patent/JP5643467B2/ja not_active Expired - Fee Related
- 2012-06-21 AU AU2012276179A patent/AU2012276179B2/en not_active Ceased
- 2012-06-21 CN CN201280031707.8A patent/CN103649071B/zh not_active Expired - Fee Related
- 2012-06-21 WO PCT/CN2012/000863 patent/WO2013000273A1/en active Application Filing
- 2012-06-21 KR KR1020147001631A patent/KR101478597B1/ko active IP Right Grant
- 2012-06-21 BR BR112013033559A patent/BR112013033559A2/pt active Search and Examination
- 2012-06-21 PL PL12803844T patent/PL2723727T3/pl unknown
- 2012-06-21 ES ES12803844.5T patent/ES2626024T3/es active Active
- 2012-06-21 EP EP12803844.5A patent/EP2723727B1/en not_active Not-in-force
- 2012-06-21 RU RU2014102378/04A patent/RU2558145C1/ru active
-
2014
- 2014-03-27 HK HK14103006.0A patent/HK1189887A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US8809590B2 (en) | 2014-08-19 |
EP2723727B1 (en) | 2017-03-01 |
RU2558145C1 (ru) | 2015-07-27 |
KR20140027492A (ko) | 2014-03-06 |
KR101478597B1 (ko) | 2015-01-02 |
BR112013033559A2 (pt) | 2016-08-16 |
ES2626024T3 (es) | 2017-07-21 |
CN103649071B (zh) | 2014-07-30 |
CN103649071A (zh) | 2014-03-19 |
PL2723727T3 (pl) | 2017-08-31 |
AU2012276179A1 (en) | 2014-01-16 |
CA2839366C (en) | 2015-01-20 |
EP2723727A1 (en) | 2014-04-30 |
WO2013000273A1 (en) | 2013-01-03 |
US20140121380A1 (en) | 2014-05-01 |
EP2723727A4 (en) | 2015-01-07 |
AU2012276179B2 (en) | 2015-09-24 |
JP5643467B2 (ja) | 2014-12-17 |
JP2014523428A (ja) | 2014-09-11 |
CA2839366A1 (en) | 2013-01-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20210619 |