HK1156056A1 - 經修飾的抗-肝素/ 複合物抗體以及 抗體標準 - Google Patents
經修飾的抗-肝素/ 複合物抗體以及 抗體標準Info
- Publication number
- HK1156056A1 HK1156056A1 HK11110584.8A HK11110584A HK1156056A1 HK 1156056 A1 HK1156056 A1 HK 1156056A1 HK 11110584 A HK11110584 A HK 11110584A HK 1156056 A1 HK1156056 A1 HK 1156056A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hit
- antibody
- heparin
- modified anti
- standard
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/22—Haematology
- G01N2800/222—Platelet disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008218801 | 2008-08-27 | ||
PCT/JP2009/064828 WO2010024271A1 (ja) | 2008-08-27 | 2009-08-26 | 修飾抗ヘパリン/pf4複合体抗体及びhit抗体標準品 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1156056A1 true HK1156056A1 (zh) | 2012-06-01 |
Family
ID=41721438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11110584.8A HK1156056A1 (zh) | 2008-08-27 | 2011-10-06 | 經修飾的抗-肝素/ 複合物抗體以及 抗體標準 |
Country Status (6)
Country | Link |
---|---|
US (1) | US9322825B2 (zh) |
EP (1) | EP2330128B1 (zh) |
JP (1) | JP5618831B2 (zh) |
ES (1) | ES2561984T3 (zh) |
HK (1) | HK1156056A1 (zh) |
WO (1) | WO2010024271A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011113601A1 (en) * | 2010-03-17 | 2011-09-22 | Biogenerix Ag | Method for obtaining biologically active recombinant human g-csf |
US9599623B2 (en) | 2011-06-09 | 2017-03-21 | Immucor Gti Diagnostics, Inc. | Diagnostic devices, methods and systems for detecting platelet factor 4 (PF4)/heparin antibodies |
US9851367B2 (en) | 2013-10-29 | 2017-12-26 | Blood Center Research Foundation | Method of detection of platelet-activating antibodies that cause heparin-induced thrombocytopenia/thrombosis |
CN113603774B (zh) * | 2021-08-27 | 2022-02-25 | 上海赫景生物技术有限公司 | 一种单克隆抗体及其在疾病诊断和检测中的应用 |
CN113583123B (zh) * | 2021-08-27 | 2022-03-29 | 贵州安康医学检验中心有限公司 | 一种血浆中肝素含量的检测方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3800048A1 (de) * | 1987-05-14 | 1988-11-24 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines antikoerpers in menschlichen koerperfluessigkeiten |
DE3729035A1 (de) | 1987-08-31 | 1989-03-09 | Hoechst Ag | Positiv arbeitendes lichtempfindliches gemisch und daraus hergestelltes photolithographisches aufzeichnungsmaterial |
FR2665769B1 (fr) * | 1990-08-09 | 1994-04-29 | Serbio | Determination des thrombopenies notamment induites par l'heparine au moyen du facteur plaquettaire 4. |
US5466582A (en) * | 1990-08-09 | 1995-11-14 | Serbio | Thrombocytopenia determination |
CA2072758A1 (en) * | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
US5478753A (en) | 1993-06-29 | 1995-12-26 | Pb Diagnostic Systems, Inc. | Positive calibrator/control composition for an IgM serology assay and an IgM serology assay |
DE69633780T3 (de) * | 1995-04-18 | 2011-05-05 | Biosite Incorporated, San Diego | Verfahren zum assay von troponin i und t und komplexen von troponin i und t und auswahl von antikörpern zur verwendung in immunoassays |
US5972717A (en) * | 1995-05-10 | 1999-10-26 | The Blood Center Research Foundation, Inc. | Method and kit for detecting heparin induced thrombocytopenia |
US5972718A (en) * | 1996-02-28 | 1999-10-26 | The Blood Center Research Foundation | Method of detecting heparin-induced thrombocytopenia |
US6964854B1 (en) * | 1999-07-13 | 2005-11-15 | Science & Technology Corporation | Compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis |
WO2001016184A2 (en) * | 1999-08-30 | 2001-03-08 | Mustapha Abdelouahed | Diagnostic assay for type 2 heparin-induced thrombocytopenia |
CA2582626A1 (en) * | 2004-10-04 | 2006-04-20 | Akers Biosciences, Inc. | Methods and kits for detecting heparin/platelet factor 4 antibodies |
US20070190582A1 (en) * | 2005-12-20 | 2007-08-16 | Mortimer Poncz | Platelet surface PF4 antigenic complexes as a diagnostic indicator in heparin-induced thrombocytopenia |
US20100009389A1 (en) * | 2008-07-14 | 2010-01-14 | Masood Unnabi Khan | Method of Making and Using Versatile Positive Controls and Antibody Detection Assays |
-
2009
- 2009-08-26 JP JP2010526729A patent/JP5618831B2/ja active Active
- 2009-08-26 WO PCT/JP2009/064828 patent/WO2010024271A1/ja active Application Filing
- 2009-08-26 EP EP09809922.9A patent/EP2330128B1/en active Active
- 2009-08-26 ES ES09809922.9T patent/ES2561984T3/es active Active
- 2009-08-26 US US13/061,072 patent/US9322825B2/en active Active
-
2011
- 2011-10-06 HK HK11110584.8A patent/HK1156056A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP2330128A4 (en) | 2012-12-19 |
US20110171753A1 (en) | 2011-07-14 |
EP2330128A1 (en) | 2011-06-08 |
ES2561984T3 (es) | 2016-03-01 |
WO2010024271A1 (ja) | 2010-03-04 |
JP5618831B2 (ja) | 2014-11-05 |
EP2330128B1 (en) | 2015-12-23 |
US9322825B2 (en) | 2016-04-26 |
JPWO2010024271A1 (ja) | 2012-01-26 |
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