HK1155170A1 - Pyridine compounds - Google Patents

Pyridine compounds

Info

Publication number
HK1155170A1
HK1155170A1 HK11109503.8A HK11109503A HK1155170A1 HK 1155170 A1 HK1155170 A1 HK 1155170A1 HK 11109503 A HK11109503 A HK 11109503A HK 1155170 A1 HK1155170 A1 HK 1155170A1
Authority
HK
Hong Kong
Prior art keywords
pyridine compounds
pyridine
compounds
Prior art date
Application number
HK11109503.8A
Other languages
English (en)
Chinese (zh)
Inventor
Bernard Christophe Barlaam
Kevin Michael Foote
Patrick Ple
Clifford David Jones
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1155170A1 publication Critical patent/HK1155170A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
HK11109503.8A 2008-06-17 2011-09-08 Pyridine compounds HK1155170A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7305508P 2008-06-17 2008-06-17
PCT/GB2009/050675 WO2009153589A1 (en) 2008-06-17 2009-06-15 Pyridine compounds

Publications (1)

Publication Number Publication Date
HK1155170A1 true HK1155170A1 (en) 2012-05-11

Family

ID=40896110

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11109503.8A HK1155170A1 (en) 2008-06-17 2011-09-08 Pyridine compounds

Country Status (18)

Country Link
US (1) US8569298B2 (ja)
EP (1) EP2303861B1 (ja)
JP (1) JP5551689B2 (ja)
KR (1) KR101695501B1 (ja)
CN (1) CN102124000B (ja)
AU (1) AU2009261764B2 (ja)
BR (1) BRPI0914927B8 (ja)
CA (1) CA2726508C (ja)
CR (1) CR11854A (ja)
DO (1) DOP2010000390A (ja)
EA (1) EA020807B1 (ja)
EC (1) ECSP10010695A (ja)
ES (1) ES2472323T3 (ja)
HK (1) HK1155170A1 (ja)
IL (1) IL209727A0 (ja)
MX (1) MX2010014057A (ja)
WO (1) WO2009153589A1 (ja)
ZA (1) ZA201100388B (ja)

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US20140155410A1 (en) * 2008-10-27 2014-06-05 Glaxosmithkline Llc Pyrazolylaminopyridines as inhibitors of fak
JO3067B1 (ar) 2008-10-27 2017-03-15 Glaxosmithkline Llc بيرميدينات بيرازولو امينو كمثبطات ل fak
WO2010068947A2 (en) * 2008-12-12 2010-06-17 H. Lee Moffitt Cancer Center And Research Institute, Inc. Nuclear export inhibitors of topoisomerase ii alpha
US8952034B2 (en) 2009-07-27 2015-02-10 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
RU2528386C2 (ru) 2010-05-21 2014-09-20 Кемилиа Аб Новые производные пиримидина
AU2011276552B2 (en) 2010-06-29 2015-09-03 Verastem, Inc. Oral formulation of kinase inhibitors
NZ604801A (en) 2010-06-30 2015-03-27 Verastem Inc Synthesis and use of focal adhesion kinase inhibitors
WO2012003392A1 (en) 2010-07-02 2012-01-05 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
US20120244141A1 (en) 2010-09-28 2012-09-27 Boehringer Ingelheim International Gmbh Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors
KR20140011322A (ko) * 2011-01-26 2014-01-28 글락소스미스클라인 인털렉츄얼 프로퍼티 리미티드 조합물
WO2012110774A1 (en) 2011-02-17 2012-08-23 Cancer Therapeutics Crc Pty Limited Selective fak inhibitors
AU2012216893B2 (en) 2011-02-17 2016-08-11 Cancer Therapeutics Crc Pty Limited FAK inhibitors
CA2830129C (en) 2011-03-24 2016-07-19 Chemilia Ab Novel pyrimidine derivatives
EP2707361B1 (en) 2011-05-10 2017-08-23 Gilead Sciences, Inc. Fused heterocyclic compounds as sodium channel modulators
TWI549944B (zh) 2011-07-01 2016-09-21 吉李德科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
NO3175985T3 (ja) 2011-07-01 2018-04-28
TW201341367A (zh) 2012-03-16 2013-10-16 Axikin Pharmaceuticals Inc 3,5-二胺基吡唑激酶抑制劑
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
SG11201609386YA (en) * 2014-06-17 2017-01-27 Pfizer Substituted dihydroisoquinolinone compounds
US9442005B2 (en) 2014-07-30 2016-09-13 Corning Optical Communications LLC Non-contact methods of measuring insertion loss in optical fiber connectors
CN107250116B (zh) 2014-12-23 2020-10-27 艾士盟医疗公司 3,5-二氨基吡唑激酶抑制剂
GB201510010D0 (en) 2015-06-09 2015-07-22 King S College London PDD and BPD compounds
AU2016286091B2 (en) 2015-06-29 2021-02-04 Verastem, Inc. Therapeutic compositions, combinations, and methods of use
GB201514928D0 (en) 2015-08-21 2015-10-07 King S College London PDD compounds
US20180339985A1 (en) 2015-08-21 2018-11-29 Femtogenix Limited Pdd compounds
JP7444780B2 (ja) 2018-02-28 2024-03-06 ビーエーエスエフ ソシエタス・ヨーロピア 硝化阻害剤としてのn-官能化アルコキシピラゾール化合物の使用
CA3089381A1 (en) 2018-02-28 2019-09-06 Basf Se Use of pyrazole propargyl ethers as nitrification inhibitors
CN112218658A (zh) 2018-03-12 2021-01-12 国家健康科学研究所 热量限制模拟物用于增强癌症治疗的化学免疫疗法的用途
CN108912095B (zh) * 2018-08-09 2019-08-20 广州安岩仁医药科技有限公司 苯并咪唑类化合物及其制备方法和应用
CN114793434A (zh) * 2019-10-18 2022-07-26 加利福尼亚大学董事会 作为用于治疗病原性血管病症的药剂的3-苯基磺酰基-喹啉衍生物
BR112023024208A2 (pt) 2021-05-21 2024-01-30 Basf Se Uso de um composto, composição, mistura agroquímica e métodos para reduzir nitrificação e para tratar um fertilizante

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Publication number Priority date Publication date Assignee Title
GB0004890D0 (en) 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds
GB0305929D0 (en) 2003-03-14 2003-04-23 Novartis Ag Organic compounds
DE10336184A1 (de) 2003-08-07 2005-02-24 Bayer Materialscience Ag Neue Katalysatoren für die selektive Isocyanatdimerisierung
CA2533320A1 (en) * 2003-08-15 2006-02-24 Novartis Ag 2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
BRPI0512342A (pt) 2004-06-21 2008-03-04 Pharmacia & Upjohn Co Llc métodos para aumento ósseo
GB0419161D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
GB0419160D0 (en) 2004-08-27 2004-09-29 Novartis Ag Organic compounds
EP1841760B1 (en) 2004-12-30 2011-08-10 Exelixis, Inc. Pyrimidine derivatives as kinase modulators and method of use
CA2632149C (en) * 2005-12-01 2011-11-15 Pfizer Products Inc. Pyrimidine derivatives for the treatment of abnormal cell growth
UA89123C2 (ru) 2005-12-21 2009-12-25 Пфайзер Продактс Инк. Производные пиримидина для лечения абнормального роста клеток
JP5208123B2 (ja) 2006-12-08 2013-06-12 アイアールエム・リミテッド・ライアビリティ・カンパニー タンパク質キナーゼ阻害剤としての化合物および組成物
CA2681015C (en) * 2007-03-16 2016-06-21 The Scripps Research Institute Inhibitors of focal adhesion kinase
US20100190777A1 (en) * 2007-07-17 2010-07-29 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
EP2249650A4 (en) * 2008-02-19 2012-01-11 Glaxosmithkline Llc ANILINOPYRIDINE AS A FAK HEMMER

Also Published As

Publication number Publication date
CN102124000B (zh) 2014-09-17
BRPI0914927B1 (pt) 2020-10-06
KR20110023884A (ko) 2011-03-08
AU2009261764A1 (en) 2009-12-23
MX2010014057A (es) 2011-03-21
BRPI0914927A2 (pt) 2017-06-20
JP5551689B2 (ja) 2014-07-16
CA2726508A1 (en) 2009-12-23
ES2472323T3 (es) 2014-06-30
WO2009153589A1 (en) 2009-12-23
KR101695501B1 (ko) 2017-01-11
AU2009261764B2 (en) 2013-01-10
US8569298B2 (en) 2013-10-29
EP2303861B1 (en) 2014-04-23
EA201100032A1 (ru) 2012-01-30
BRPI0914927B8 (pt) 2021-05-25
EP2303861A1 (en) 2011-04-06
JP2011524411A (ja) 2011-09-01
IL209727A0 (en) 2011-02-28
ECSP10010695A (es) 2011-01-31
CN102124000A (zh) 2011-07-13
DOP2010000390A (es) 2011-01-15
EA020807B1 (ru) 2015-01-30
CR11854A (es) 2011-02-25
US20110166139A1 (en) 2011-07-07
ZA201100388B (en) 2011-10-26
CA2726508C (en) 2016-06-07

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