HK1138504A1 - 放射性診斷顯像劑的製備方法 - Google Patents

放射性診斷顯像劑的製備方法

Info

Publication number
HK1138504A1
HK1138504A1 HK10104126.7A HK10104126A HK1138504A1 HK 1138504 A1 HK1138504 A1 HK 1138504A1 HK 10104126 A HK10104126 A HK 10104126A HK 1138504 A1 HK1138504 A1 HK 1138504A1
Authority
HK
Hong Kong
Prior art keywords
production
imaging agent
diagnostic imaging
radiation diagnostic
radiation
Prior art date
Application number
HK10104126.7A
Other languages
English (en)
Inventor
大作 中村
壯 中村
正人 外山
明希男 林
Original Assignee
日本醫事物理股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日本醫事物理股份有限公司 filed Critical 日本醫事物理股份有限公司
Publication of HK1138504A1 publication Critical patent/HK1138504A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C07B63/04—Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
HK10104126.7A 2007-02-13 2010-04-28 放射性診斷顯像劑的製備方法 HK1138504A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007031692 2007-02-13
PCT/JP2008/052231 WO2008099800A1 (ja) 2007-02-13 2008-02-12 放射性画像診断剤の製造方法

Publications (1)

Publication Number Publication Date
HK1138504A1 true HK1138504A1 (zh) 2010-08-27

Family

ID=39690029

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10104126.7A HK1138504A1 (zh) 2007-02-13 2010-04-28 放射性診斷顯像劑的製備方法

Country Status (10)

Country Link
US (2) US8343459B2 (zh)
EP (1) EP2119458B9 (zh)
JP (1) JP5258583B2 (zh)
KR (1) KR101485445B1 (zh)
CN (1) CN101636183B (zh)
CA (1) CA2678020C (zh)
ES (1) ES2421886T3 (zh)
HK (1) HK1138504A1 (zh)
TW (1) TWI406674B (zh)
WO (1) WO2008099800A1 (zh)

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EP2793954B1 (en) * 2011-12-21 2020-10-21 GE Healthcare Limited 18f-fluciclovine compositions in citrate buffers
US20130005958A1 (en) * 2011-06-30 2013-01-03 General Electric Company Devices and methods for reducing radiolysis of radioisotopes
US20130004414A1 (en) * 2011-06-30 2013-01-03 General Electric Company Devices and methods for reducing radiolysis of radioisotopes
US11534494B2 (en) 2011-12-21 2022-12-27 Ge Healthcare Limited Formulation and method of synthesis
GB201411569D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Novel formulation and method of synthesis
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GB201214220D0 (en) 2012-08-09 2012-09-19 Ge Healthcare Ltd Radiosynthesis
GB2561122B (en) * 2012-12-21 2019-07-17 Ge Healthcare Ltd Composition comprising [18F]-Fluciclovine
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DE102016012552A1 (de) * 2016-10-20 2018-04-26 Carl Freudenberg Kg Dichtung und Dichtungsanordnung
JP7260552B2 (ja) * 2018-01-24 2023-04-18 エーシー・イミューン・エス・アー Ｐｅｔ画像化のための診断用組成物、診断用組成物を製造するための方法及び診断におけるその使用

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Also Published As

Publication number Publication date
CN101636183B (zh) 2014-03-19
US20100119448A1 (en) 2010-05-13
CA2678020C (en) 2015-03-24
EP2119458A1 (en) 2009-11-18
JPWO2008099800A1 (ja) 2010-05-27
EP2119458B9 (en) 2013-08-21
TWI406674B (zh) 2013-09-01
US8343459B2 (en) 2013-01-01
KR20090111331A (ko) 2009-10-26
KR101485445B1 (ko) 2015-01-22
TW200833362A (en) 2008-08-16
US20120301399A1 (en) 2012-11-29
US8658132B2 (en) 2014-02-25
ES2421886T3 (es) 2013-09-06
EP2119458B1 (en) 2013-05-15
CN101636183A (zh) 2010-01-27
JP5258583B2 (ja) 2013-08-07
EP2119458A4 (en) 2010-03-24
CA2678020A1 (en) 2008-08-21
WO2008099800A1 (ja) 2008-08-21

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