HK1101856A1 - Pyrrolidine-3,4-dicarboxamide derivatives - Google Patents
Pyrrolidine-3,4-dicarboxamide derivativesInfo
- Publication number
- HK1101856A1 HK1101856A1 HK07109535.6A HK07109535A HK1101856A1 HK 1101856 A1 HK1101856 A1 HK 1101856A1 HK 07109535 A HK07109535 A HK 07109535A HK 1101856 A1 HK1101856 A1 HK 1101856A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrrolidine
- dicarboxamide derivatives
- dicarboxamide
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04101265 | 2004-03-26 | ||
PCT/EP2005/002862 WO2005092881A1 (en) | 2004-03-26 | 2005-03-17 | Novel pyrrolidine-3,4-dicarboxamide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1101856A1 true HK1101856A1 (en) | 2007-10-26 |
Family
ID=34962445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07109535.6A HK1101856A1 (en) | 2004-03-26 | 2007-09-03 | Pyrrolidine-3,4-dicarboxamide derivatives |
Country Status (27)
Country | Link |
---|---|
US (1) | US7550487B2 (hr) |
EP (1) | EP1732918B1 (hr) |
JP (1) | JP4533428B2 (hr) |
KR (1) | KR100847191B1 (hr) |
CN (1) | CN1938294B (hr) |
AR (1) | AR048589A1 (hr) |
AT (1) | ATE414075T1 (hr) |
AU (2) | AU2005225523B2 (hr) |
BR (1) | BRPI0509256B1 (hr) |
CA (1) | CA2560669C (hr) |
DE (1) | DE602005010986D1 (hr) |
DK (1) | DK1732918T3 (hr) |
ES (1) | ES2314632T3 (hr) |
HK (1) | HK1101856A1 (hr) |
HR (1) | HRP20090050T3 (hr) |
IL (1) | IL177662A (hr) |
MX (1) | MXPA06010827A (hr) |
MY (1) | MY144101A (hr) |
NO (1) | NO338531B1 (hr) |
NZ (1) | NZ549395A (hr) |
PL (1) | PL1732918T3 (hr) |
PT (1) | PT1732918E (hr) |
RU (1) | RU2379288C2 (hr) |
SI (1) | SI1732918T1 (hr) |
TW (1) | TWI295290B (hr) |
WO (1) | WO2005092881A1 (hr) |
ZA (1) | ZA200607606B (hr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602005026047D1 (de) | 2004-11-03 | 2011-03-03 | Hoffmann La Roche | Dicarbonsäureamidderivate und deren verwendung als inhibitoren von faktor xa |
WO2006135054A1 (ja) | 2005-06-16 | 2006-12-21 | Dsm Ip Assets B.V. | 光学的立体造形用放射線硬化性液状樹脂組成物及びそれを硬化させて得られる光造形物 |
WO2007053610A2 (en) * | 2005-11-01 | 2007-05-10 | The Regents Of The University Of California | Methods of treating atrial fibrillation wtih pirfenidone |
AU2007338102A1 (en) * | 2006-12-22 | 2008-07-03 | F. Hoffmann-La Roche Ag | Processes for the preparation of (3R, 4R) -N- (4 -chlorophenyl) -1- (2, 2-difluoroethyl) -N' - [2-fluoro-4- (2-oxo-1 (2H) -pyridinyl) phenyl] -3, 4-pyrrolidinedicarboxamide |
CN101679373A (zh) * | 2007-05-10 | 2010-03-24 | 弗·哈夫曼-拉罗切有限公司 | Fxa抑制剂的新固体形式 |
US8354444B2 (en) * | 2008-09-18 | 2013-01-15 | Hoffmann-La Roche Inc. | Substituted pyrrolidine-2-carboxamides |
US20110152233A1 (en) * | 2009-12-18 | 2011-06-23 | Henner Knust | Pyrrolidine compounds |
EP2676965B1 (en) | 2011-02-18 | 2017-10-04 | Shanghai Yingli Pharmaceutical Co., Ltd | Aryl glycoside compound, preparation method and use thereof |
CN115666553A (zh) * | 2020-05-27 | 2023-01-31 | 轴向治疗公司 | Tlr2调节剂化合物及其药物组合物和用途 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999065867A1 (en) * | 1998-06-17 | 1999-12-23 | Du Pont Pharmaceuticals Company | Cyclic hydroxamic acids as metalloproteinase inhibitors |
EP1183234A1 (en) * | 1999-05-24 | 2002-03-06 | Cor Therapeutics, Inc. | INHIBITORS OF FACTOR Xa |
AU2001288819A1 (en) * | 2000-09-11 | 2002-03-26 | Genentech, Inc. | Amidine inhibitors of serine proteases |
US7030141B2 (en) | 2001-11-29 | 2006-04-18 | Christopher Franklin Bigge | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
US7205318B2 (en) * | 2003-03-18 | 2007-04-17 | Bristol-Myers Squibb Company | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors |
DE602005026047D1 (de) | 2004-11-03 | 2011-03-03 | Hoffmann La Roche | Dicarbonsäureamidderivate und deren verwendung als inhibitoren von faktor xa |
US7361672B2 (en) | 2004-12-23 | 2008-04-22 | Hoffmann-La Roche Inc. | Heteroarylacetamide inhibitors of factor Xa |
US7820699B2 (en) | 2005-04-27 | 2010-10-26 | Hoffmann-La Roche Inc. | Cyclic amines |
CA2614401A1 (en) | 2005-07-15 | 2007-01-25 | F. Hoffmann-La Roche Ag | Novel heteroaryl fused cyclic amines |
US7678917B2 (en) | 2005-09-01 | 2010-03-16 | Hoffman-La Roche Inc. | Factor Xa inhibitors |
KR20080067697A (ko) | 2005-11-11 | 2008-07-21 | 에프. 호프만-라 로슈 아게 | 응고 인자 xa의 억제제로서 카보사이클릭 융합된사이클릭 아민 |
WO2007057317A1 (en) | 2005-11-16 | 2007-05-24 | F. Hoffmann-La Roche Ag | Novel pyrrolidine derivatives as inhibitors of coagulation factor xa |
EP1847537A1 (en) | 2006-04-21 | 2007-10-24 | F. Hoffmann-La Roche Ag | Dicarboxamide derivatives |
-
2005
- 2005-03-09 US US11/076,162 patent/US7550487B2/en not_active Expired - Fee Related
- 2005-03-17 NZ NZ549395A patent/NZ549395A/en not_active IP Right Cessation
- 2005-03-17 RU RU2006137661/04A patent/RU2379288C2/ru not_active IP Right Cessation
- 2005-03-17 SI SI200530524T patent/SI1732918T1/sl unknown
- 2005-03-17 ES ES05716166T patent/ES2314632T3/es active Active
- 2005-03-17 WO PCT/EP2005/002862 patent/WO2005092881A1/en active Application Filing
- 2005-03-17 JP JP2007504314A patent/JP4533428B2/ja not_active Expired - Fee Related
- 2005-03-17 PL PL05716166T patent/PL1732918T3/pl unknown
- 2005-03-17 MX MXPA06010827A patent/MXPA06010827A/es active IP Right Grant
- 2005-03-17 PT PT05716166T patent/PT1732918E/pt unknown
- 2005-03-17 DK DK05716166T patent/DK1732918T3/da active
- 2005-03-17 DE DE602005010986T patent/DE602005010986D1/de active Active
- 2005-03-17 AT AT05716166T patent/ATE414075T1/de active
- 2005-03-17 KR KR1020067019740A patent/KR100847191B1/ko active IP Right Grant
- 2005-03-17 AU AU2005225523A patent/AU2005225523B2/en not_active Ceased
- 2005-03-17 BR BRPI0509256-6A patent/BRPI0509256B1/pt not_active IP Right Cessation
- 2005-03-17 EP EP05716166A patent/EP1732918B1/en active Active
- 2005-03-17 CN CN2005800098333A patent/CN1938294B/zh not_active Expired - Fee Related
- 2005-03-17 CA CA2560669A patent/CA2560669C/en not_active Expired - Fee Related
- 2005-03-22 TW TW094108790A patent/TWI295290B/zh not_active IP Right Cessation
- 2005-03-23 AR ARP050101146A patent/AR048589A1/es not_active Application Discontinuation
- 2005-03-24 MY MYPI20051293A patent/MY144101A/en unknown
-
2006
- 2006-08-23 IL IL177662A patent/IL177662A/en active IP Right Grant
- 2006-09-11 ZA ZA200607606A patent/ZA200607606B/en unknown
- 2006-10-24 NO NO20064821A patent/NO338531B1/no not_active IP Right Cessation
-
2007
- 2007-09-03 HK HK07109535.6A patent/HK1101856A1/xx not_active IP Right Cessation
-
2009
- 2009-01-27 HR HR20090050T patent/HRP20090050T3/hr unknown
-
2012
- 2012-01-13 AU AU2012200212A patent/AU2012200212A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20200315 |