HK1100226A1 - Compositions comprising fetal liver cells and methods useful for hcv infection - Google Patents
Compositions comprising fetal liver cells and methods useful for hcv infectionInfo
- Publication number
- HK1100226A1 HK1100226A1 HK07108310.9A HK07108310A HK1100226A1 HK 1100226 A1 HK1100226 A1 HK 1100226A1 HK 07108310 A HK07108310 A HK 07108310A HK 1100226 A1 HK1100226 A1 HK 1100226A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- liver cells
- hcv infection
- methods useful
- fetal liver
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
- C12N2500/14—Calcium; Ca chelators; Calcitonin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/18—Liver cell growth factor (LCGF, Gly-His-Lys)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/335—Glucagon; Glucagon-like peptide [GLP]; Exendin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52641103P | 2003-12-01 | 2003-12-01 | |
PCT/US2004/039964 WO2005054450A1 (fr) | 2003-12-01 | 2004-12-01 | Compositions renfermant des cellules hepatiques foetales, et procedes utiles pour le traitement de l'infection par le vhc |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1100226A1 true HK1100226A1 (en) | 2007-09-14 |
Family
ID=34652451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07108310.9A HK1100226A1 (en) | 2003-12-01 | 2007-07-30 | Compositions comprising fetal liver cells and methods useful for hcv infection |
Country Status (8)
Country | Link |
---|---|
US (1) | US20050287514A1 (fr) |
EP (1) | EP1689857A1 (fr) |
JP (1) | JP2007516706A (fr) |
CN (1) | CN1910275B (fr) |
AU (1) | AU2004295702A1 (fr) |
CA (1) | CA2547787A1 (fr) |
HK (1) | HK1100226A1 (fr) |
WO (1) | WO2005054450A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA66767C2 (uk) | 1996-10-18 | 2004-06-15 | Вертекс Фармасьютикалс Інкорпорейтед | Інгібітори серин-протеаз, фармацевтична композиція, спосіб інгібування активності та спосіб лікування або профілактики вірусної інфекції гепатиту с |
SV2003000617A (es) * | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
TWI359147B (en) | 2003-09-05 | 2012-03-01 | Vertex Pharma | Inhibitors of serine proteases, particularly hcv n |
AR055395A1 (es) | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
US7964624B1 (en) | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
WO2007046962A2 (fr) * | 2005-09-02 | 2007-04-26 | The University Of Maryland, Baltimore | Lignees cellulaires hebergeant le virus de l'hepatite et procedes d'utilisation de celles-ci |
JP4921083B2 (ja) * | 2005-09-13 | 2012-04-18 | タカラバイオ株式会社 | レトロウィルス産生用無血清培地 |
US8039475B2 (en) | 2006-02-27 | 2011-10-18 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical compositions comprising the same |
WO2007109080A2 (fr) | 2006-03-16 | 2007-09-27 | Vertex Pharmaceuticals Incorporated | Inhibiteurs de protéase de l'hépatite c deutérés |
CN101903392A (zh) | 2007-02-27 | 2010-12-01 | 弗特克斯药品有限公司 | 丝氨酸蛋白酶的抑制剂 |
JP2010519330A (ja) | 2007-02-27 | 2010-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッド | 共結晶体およびそれを含む医薬組成物 |
CN101835774B (zh) | 2007-08-30 | 2014-09-17 | 弗特克斯药品有限公司 | 共晶体和包含该共晶体的药物组合物 |
JP2009254292A (ja) * | 2008-04-17 | 2009-11-05 | Tosoh Corp | 細胞融合装置及び細胞融合方法 |
CN101463345B (zh) * | 2008-12-26 | 2012-03-21 | 青岛易邦生物工程有限公司 | 一种病毒繁殖促进剂及其应用 |
JP2015092852A (ja) * | 2013-11-12 | 2015-05-18 | 倉敷紡績株式会社 | 生体組織分散用組成物 |
EP3595686A4 (fr) * | 2017-02-01 | 2020-12-02 | PhoenixSongs Biologicals, Inc. | Compositions et procédés comprenant la co-culture d'hépatocytes |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5529920A (en) * | 1988-12-14 | 1996-06-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human liver epithelial cell line and culture media therefor |
WO1992003046A1 (fr) * | 1990-08-28 | 1992-03-05 | Somatix Therapy Corporation | Procede ameliore de cryoconservation de cellules |
US5849686A (en) * | 1991-03-11 | 1998-12-15 | Creative Biomolecules, Inc. | Morphogen-induced liver regeneration |
US5723282A (en) * | 1991-07-08 | 1998-03-03 | The American National Red Cross | Method of preparing organs for vitrification |
US6069005A (en) * | 1991-08-07 | 2000-05-30 | Albert Einstein College Of Medicine Of Yeshwa University | Hapatoblasts and method of isolating same |
JPH07501206A (ja) * | 1991-08-07 | 1995-02-09 | イェシバ・ユニバーシティ | 前駆肝細胞の増殖 |
US6127116A (en) * | 1995-08-29 | 2000-10-03 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
US5795711A (en) * | 1996-04-04 | 1998-08-18 | Circe Biomedical, Inc. | Cryopreserved hepatocytes and high viability and metabolic activity |
US6331406B1 (en) * | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
EP0972828A1 (fr) * | 1998-06-24 | 2000-01-19 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Procés pour la réplication in vitro du HCV |
US6787356B1 (en) * | 1998-07-24 | 2004-09-07 | The United States Of America As Represented By The Department Of Health And Human Services | Cell expansion system for use in neural transplantation |
KR19990014353A (ko) * | 1998-10-17 | 1999-02-25 | 윤태욱 | 췌도의 대량 배양증식방법 |
US6667176B1 (en) * | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
HUP0203781A2 (hu) * | 2000-01-19 | 2003-03-28 | University Of North Carolina At Chapel Hill | Májszövet-forrás |
US20020045156A1 (en) * | 2000-05-16 | 2002-04-18 | Mehmet Toner | Microinjection of cryoprotectants for preservation of cells |
US6762053B2 (en) * | 2000-06-09 | 2004-07-13 | Vitrolife, Inc. | Mammalian gamete and embryo culture media and culture media supplements |
US6521402B1 (en) * | 2000-06-14 | 2003-02-18 | The Texas A&M University System | Cryopreservation of tissues for use in nuclear transfer |
US6656170B2 (en) * | 2000-12-08 | 2003-12-02 | Sca Hygiene Products Ab | Absorbent article with improved leakage safety |
CA2441688C (fr) * | 2001-03-27 | 2014-01-21 | Vertex Pharmaceuticals Incorporated | Compositions et methodes de traitement de l'infection par le vhc |
US7150991B2 (en) * | 2002-04-01 | 2006-12-19 | Virginia Tech Intellectual Properties, Inc. | Method to preserve cells |
WO2004003172A2 (fr) * | 2002-07-01 | 2004-01-08 | Pharmacia Corporation | Gene esm-1 exprime differentiellement dans l'angiogenese, antagonistes de dernier et methodes d'utilisation correspondantes |
-
2004
- 2004-12-01 AU AU2004295702A patent/AU2004295702A1/en not_active Abandoned
- 2004-12-01 JP JP2006542663A patent/JP2007516706A/ja active Pending
- 2004-12-01 WO PCT/US2004/039964 patent/WO2005054450A1/fr active Application Filing
- 2004-12-01 US US11/001,686 patent/US20050287514A1/en not_active Abandoned
- 2004-12-01 CN CN2004800411747A patent/CN1910275B/zh not_active Expired - Fee Related
- 2004-12-01 CA CA002547787A patent/CA2547787A1/fr not_active Abandoned
- 2004-12-01 EP EP04812485A patent/EP1689857A1/fr not_active Withdrawn
-
2007
- 2007-07-30 HK HK07108310.9A patent/HK1100226A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1910275A (zh) | 2007-02-07 |
CN1910275B (zh) | 2011-04-27 |
AU2004295702A1 (en) | 2005-06-16 |
CA2547787A1 (fr) | 2005-06-16 |
JP2007516706A (ja) | 2007-06-28 |
US20050287514A1 (en) | 2005-12-29 |
EP1689857A1 (fr) | 2006-08-16 |
WO2005054450A1 (fr) | 2005-06-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20141201 |