HK1087409A1 - Novel heteroaryl derivative - Google Patents

Novel heteroaryl derivative

Info

Publication number
HK1087409A1
HK1087409A1 HK06109338.6A HK06109338A HK1087409A1 HK 1087409 A1 HK1087409 A1 HK 1087409A1 HK 06109338 A HK06109338 A HK 06109338A HK 1087409 A1 HK1087409 A1 HK 1087409A1
Authority
HK
Hong Kong
Prior art keywords
optionally substituted
heteroaryl derivative
heteroaryl
novel heteroaryl
single bond
Prior art date
Application number
HK06109338.6A
Other languages
English (en)
Inventor
Ken-Ichi Watanabe
Katsunori Maruta
Kantaro Ushiroda
Ryu Nagata
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Publication of HK1087409A1 publication Critical patent/HK1087409A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
HK06109338.6A 2003-07-15 2006-08-22 Novel heteroaryl derivative HK1087409A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003274684 2003-07-15
PCT/JP2004/010282 WO2005012245A1 (ja) 2003-07-15 2004-07-13 新規ヘテロアリール誘導体

Publications (1)

Publication Number Publication Date
HK1087409A1 true HK1087409A1 (en) 2006-10-13

Family

ID=34113749

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06109338.6A HK1087409A1 (en) 2003-07-15 2006-08-22 Novel heteroaryl derivative

Country Status (12)

Country Link
US (2) US7425642B2 (ja)
EP (1) EP1647546B1 (ja)
JP (2) JP4820169B2 (ja)
KR (1) KR101086654B1 (ja)
CN (1) CN100516041C (ja)
AT (1) ATE556051T1 (ja)
CA (1) CA2531064C (ja)
ES (1) ES2383895T3 (ja)
HK (1) HK1087409A1 (ja)
MX (1) MXPA06000539A (ja)
TW (1) TW200523249A (ja)
WO (1) WO2005012245A1 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1837329A4 (en) * 2005-01-14 2009-08-05 Dainippon Sumitomo Pharma Co NEW HETEROARYL DERIVATIVE
US20060241073A1 (en) * 2005-04-20 2006-10-26 Wanders Ronaldus J A Means and methods for counteracting fatty acid accumulation
CN101511796B (zh) 2006-09-05 2012-05-09 协和发酵麒麟株式会社 咪唑衍生物
WO2008157537A2 (en) * 2007-06-19 2008-12-24 Ironwood Pharmaceuticals, Inc Compositions and methods of use for treating or preventing lipid related disorders
JPWO2010050422A1 (ja) * 2008-10-31 2012-03-29 大日本住友製薬株式会社 糖尿病治療剤
US20120010264A1 (en) * 2009-03-26 2012-01-12 Dainippon Sumitomo Pharma Co., Ltd. Novel medicament for treating cognitive impairment
JPWO2011002012A1 (ja) * 2009-07-01 2012-12-13 キッセイ薬品工業株式会社 Ｓｇｌｔ１阻害薬とインスリン抵抗性改善薬を組み合わせてなる医薬
BR112012018631A8 (pt) 2010-01-28 2017-12-19 President And Fellows Of Harvard Colege composições e métodos para intensificação da atividade do proteassoma
WO2012007500A2 (de) 2010-07-15 2012-01-19 Bayer Cropscience Ag Neue heterocyclische verbindungen als schädlingsbekämpfungsmittel
EP2707101B1 (en) 2011-05-12 2019-02-13 Proteostasis Therapeutics, Inc. Proteostasis regulators
US10266490B2 (en) * 2012-03-16 2019-04-23 Georgetown University Radioprotector compounds
WO2014116228A1 (en) 2013-01-25 2014-07-31 President And Fellows Of Harvard College Usp14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752361A1 (de) * 1977-11-24 1979-06-07 Troponwerke Gmbh & Co Kg Neue indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO1998040385A1 (en) 1997-03-07 1998-09-17 Novo Nordisk A/S 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE
US6177443B1 (en) 1997-03-07 2001-01-23 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use
EP1284260A4 (en) 2000-05-22 2004-03-31 Takeda Chemical Industries Ltd TYROSINE PHOSPHATASE INHIBITORS
JP2002121186A (ja) 2000-05-22 2002-04-23 Takeda Chem Ind Ltd チロシンホスファターゼ阻害剤
CN100351253C (zh) 2000-06-26 2007-11-28 辉瑞产品公司 作为免疫抑制剂的吡咯并[2,3－d]嘧啶化合物
EP1386913B1 (en) * 2001-04-19 2008-07-16 Dainippon Sumitomo Pharma Co., Ltd. Pyrrole derivative
JP2003171275A (ja) 2001-12-11 2003-06-17 Sumitomo Pharmaceut Co Ltd ＰＰＡＲδアゴニスト
WO2004048341A1 (ja) 2002-11-28 2004-06-10 Sumitomo Pharmaceuticals Co., Ltd. 新規ヘテロアリール誘導体

Also Published As

Publication number Publication date
US7425642B2 (en) 2008-09-16
CA2531064C (en) 2012-05-22
US20080306275A1 (en) 2008-12-11
US20060194857A1 (en) 2006-08-31
EP1647546A4 (en) 2008-07-23
CA2531064A1 (en) 2005-02-10
MXPA06000539A (es) 2006-03-30
CN1849303A (zh) 2006-10-18
ES2383895T3 (es) 2012-06-27
EP1647546A1 (en) 2006-04-19
EP1647546B1 (en) 2012-05-02
ATE556051T1 (de) 2012-05-15
TWI331142B (ja) 2010-10-01
JPWO2005012245A1 (ja) 2006-09-14
KR20060040681A (ko) 2006-05-10
JP2011251974A (ja) 2011-12-15
TW200523249A (en) 2005-07-16
WO2005012245A1 (ja) 2005-02-10
JP4820169B2 (ja) 2011-11-24
CN100516041C (zh) 2009-07-22
KR101086654B1 (ko) 2011-11-24

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160713