HK1080733A1 - Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol - Google Patents

Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol

Info

Publication number
HK1080733A1
HK1080733A1 HK06100803A HK06100803A HK1080733A1 HK 1080733 A1 HK1080733 A1 HK 1080733A1 HK 06100803 A HK06100803 A HK 06100803A HK 06100803 A HK06100803 A HK 06100803A HK 1080733 A1 HK1080733 A1 HK 1080733A1
Authority
HK
Hong Kong
Prior art keywords
bisphosphonates
taxol
cox
inhibitor
malignancies
Prior art date
Application number
HK06100803A
Other languages
English (en)
Inventor
Lipton Allan
Witter Lois Mary
Green Jonathan
Original Assignee
Novartis Ag
Lipton Allan
Lois Mary Witters
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Lipton Allan, Lois Mary Witters filed Critical Novartis Ag
Publication of HK1080733A1 publication Critical patent/HK1080733A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK06100803A 2001-10-19 2006-01-18 Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol HK1080733A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34592101P 2001-10-19 2001-10-19
PCT/EP2002/011696 WO2003035081A1 (en) 2001-10-19 2002-10-18 Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol

Publications (1)

Publication Number Publication Date
HK1080733A1 true HK1080733A1 (en) 2006-05-04

Family

ID=23357099

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06100803A HK1080733A1 (en) 2001-10-19 2006-01-18 Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol

Country Status (26)

Country Link
US (1) US7345088B2 (xx)
EP (1) EP1443942B1 (xx)
JP (1) JP2005506371A (xx)
KR (1) KR20040066103A (xx)
CN (1) CN100372539C (xx)
AT (1) ATE382347T1 (xx)
AU (1) AU2002363089B2 (xx)
BR (1) BR0213410A (xx)
CA (1) CA2461085A1 (xx)
CO (1) CO5570672A2 (xx)
DE (1) DE60224429T2 (xx)
DK (1) DK1443942T3 (xx)
EC (1) ECSP045054A (xx)
ES (1) ES2301710T3 (xx)
HK (1) HK1080733A1 (xx)
HU (1) HUP0402061A3 (xx)
IL (2) IL161090A0 (xx)
MX (1) MXPA04003671A (xx)
NO (1) NO20042056L (xx)
NZ (1) NZ532282A (xx)
PL (1) PL367707A1 (xx)
PT (1) PT1443942E (xx)
RU (1) RU2317819C2 (xx)
SI (1) SI1443942T1 (xx)
WO (1) WO2003035081A1 (xx)
ZA (1) ZA200402089B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0204756D0 (en) * 2002-02-28 2002-04-17 Novartis Ag Organic compounds
GB0328040D0 (en) * 2003-12-03 2004-01-07 Coleman Robert E Pharmaceutical uses of bisphosphonates
FR2939314A1 (fr) * 2008-12-04 2010-06-11 Univ Victor Segalen Bordeaux 2 Nouvelles compositions et methodes pour la potentialisation des signaux d'apoptose dans les cellules tumorales
AU2010278860B2 (en) 2009-07-31 2016-05-26 Thar Pharma, Llc Crystallization method and bioavailability
US9169279B2 (en) 2009-07-31 2015-10-27 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
US20160016982A1 (en) 2009-07-31 2016-01-21 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
US9340565B2 (en) 2010-11-24 2016-05-17 Thar Pharmaceuticals, Inc. Crystalline forms
US10195218B2 (en) 2016-05-31 2019-02-05 Grunenthal Gmbh Crystallization method and bioavailability

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1187130A (zh) * 1995-06-06 1998-07-08 麦克公司 用二磷酸盐预防与免疫抑制疗法有关的骨损失
AU2713500A (en) * 1998-12-23 2000-07-31 G.D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
WO2001054688A1 (en) * 2000-01-28 2001-08-02 Merck & Co., Inc. Treatment or prevention of prostate cancer with a cox-2 selective inhibiting drug

Also Published As

Publication number Publication date
CA2461085A1 (en) 2003-05-01
EP1443942B1 (en) 2008-01-02
DE60224429T2 (de) 2008-12-18
NZ532282A (en) 2006-02-24
HUP0402061A2 (hu) 2005-02-28
HUP0402061A3 (en) 2007-05-29
JP2005506371A (ja) 2005-03-03
ZA200402089B (en) 2005-06-22
PT1443942E (pt) 2008-04-07
MXPA04003671A (es) 2005-06-20
ECSP045054A (es) 2004-05-28
CN1703226A (zh) 2005-11-30
EP1443942A1 (en) 2004-08-11
BR0213410A (pt) 2004-11-03
PL367707A1 (en) 2005-03-07
RU2004115337A (ru) 2005-04-20
CO5570672A2 (es) 2005-10-31
DE60224429D1 (de) 2008-02-14
AU2002363089B2 (en) 2006-02-16
KR20040066103A (ko) 2004-07-23
IL161090A0 (en) 2004-08-31
ES2301710T3 (es) 2008-07-01
CN100372539C (zh) 2008-03-05
WO2003035081A1 (en) 2003-05-01
ATE382347T1 (de) 2008-01-15
US7345088B2 (en) 2008-03-18
IL161090A (en) 2010-04-15
RU2317819C2 (ru) 2008-02-27
SI1443942T1 (sl) 2008-08-31
NO20042056L (no) 2004-05-18
DK1443942T3 (da) 2008-05-19
US20050014726A1 (en) 2005-01-20

Similar Documents

Publication Publication Date Title
HK1080733A1 (en) Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol
DK1373215T3 (da) Gelanamycinderivater egnet til behandling af cancer
MY141584A (en) Pharmaceutical uses of bisphosphonates
NO20063373L (no) CD40-antistoff-formuleringer og fremgangsmater
GB0001309D0 (en) Valve arrangement
HK1059213A1 (en) Treatment of type 2 diabetes with inhibitors of dipetidyl peptidase iv
UA86344C2 (ru) Способ лечения сосудистых заболеваний
DE60324427D1 (de) Verfahren zur modulation der tubulindeacetylase-aktivität
RS20050344A (xx) Tretiranje hemoragijskog šoka
BR0314081A (pt) Terapia de combinação compreendendo um bisfosfonato e um inibidor de hmg-coa redutase
AU2003250190A1 (en) Combination of an aromatase inhibitor with a bisphosphonate
GB0020504D0 (en) Therapeutic method
SE9902597D0 (sv) New use
BR0114856A (pt) Combinação compreendendo camptotecina e um derivado de estilbeno para o tratamento de câncer
WO2002015894A3 (en) Use of vitamin d derivatives as bone resorption inhibitors
BR0315374A (pt) Compostos orgânicos
AU2002319223A1 (en) Medicament for treating tumours and their metastases using a binding molecule against bone-sialoprotein
AU5434899A (en) Cancer treatment
RS37804A (xx) Upotreba n,n-dietil-2-/4-(fenilmetil)-fenoksi/etanamin monohidrohlorida (dppe) u terapiji raka
PL376407A1 (en) Medicament containing disorazoles and derivatives thereof for the treatment of benign and malignant tumoral diseases
TW200501958A (en) A therapeutic agent for treating a behavioral disorder
BR0315376A (pt) Combinações de benzotiadiazóis e inibidores de cox-2 para o tratamento de dor
AU2001262378A1 (en) Method for treating cryptorchidism
TW200519078A (en) 2-alkylidene-19-nor-vitamin d derivatives for the treatment of a second hip fracture
EA200600987A1 (ru) Применение сирамезина в лечении злокачественных опухолей

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111018