HK1078104A1 - Novel serine protease genes related to dppiv - Google Patents

Novel serine protease genes related to dppiv

Info

Publication number: HK1078104A1
Authority: HK; Hong Kong
Prior art keywords: dppiv; serine protease; genes related; protease genes; novel serine
Prior art date: 2000-10-12

Application number

HK05109986A

Other languages

English (en)

Inventor

Qi Steve

Akinsanya Karen

Riviere Pierre

Junien Jean-Louis

Original Assignee

Ferring Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2005-11-09

Publication date

2006-03-03

2005-11-09 Application filed by Ferring Bv filed Critical Ferring Bv

2006-03-03 Publication of HK1078104A1 publication Critical patent/HK1078104A1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Neurology (AREA)
Biochemistry (AREA)
Hematology (AREA)
Microbiology (AREA)
Cardiology (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Virology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)

HK05109986A 2000-10-12 2005-11-09 Novel serine protease genes related to dppiv HK1078104A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24011700P	2000-10-12	2000-10-12
PCT/US2001/031874 WO2002031134A2 (en)	2000-10-12	2001-10-12	Novel serine protease genes related to dppiv

Publications (1)

Publication Number	Publication Date
HK1078104A1 true HK1078104A1 (en)	2006-03-03

Family

ID=22905181

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK05109986A HK1078104A1 (en)	2000-10-12	2005-11-09	Novel serine protease genes related to dppiv

Country Status (18)

Country	Link
US (2)	US6844180B2 (xx)
EP (1)	EP1346033A2 (xx)
JP (1)	JP2004528812A (xx)
KR (1)	KR100875221B1 (xx)
CN (2)	CN100354417C (xx)
AU (2)	AU2002213138B2 (xx)
CA (1)	CA2425001A1 (xx)
CZ (1)	CZ20031301A3 (xx)
HK (1)	HK1078104A1 (xx)
HU (1)	HUP0301356A3 (xx)
IL (2)	IL155245A0 (xx)
MX (1)	MXPA03003191A (xx)
NO (1)	NO329842B1 (xx)
NZ (1)	NZ525443A (xx)
PL (1)	PL366005A1 (xx)
RU (1)	RU2305133C2 (xx)
WO (1)	WO2002031134A2 (xx)
ZA (1)	ZA200303306B (xx)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6979697B1 (en) *	1998-08-21	2005-12-27	Point Therapeutics, Inc.	Regulation of substrate activity
DE60029230T2 (de) *	1999-09-10	2007-06-06	The University Of Sydney, Sydney	Dipeptidyl-peptidasen
US20040047853A1 (en) *	2000-06-09	2004-03-11	Dahl Soren W	Purified proenzyme of dipeptidyl peptidase i (pro-dppi)
AUPR107800A0 (en) *	2000-10-27	2000-11-23	University Of Sydney, The	Peptide and nucleic acid molecule ii
GB0101760D0 (en) *	2001-01-23	2001-03-07	Glaxo Group Ltd	Novel protein
AU2002249453A1 (en) *	2001-04-24	2002-11-05	Isis Innovation Ltd	Enzyme and snp marker for disease
CA2446806A1 (en)	2001-05-11	2002-11-21	Board Of Regents, The University Of Texas System	Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26
DE10150203A1 (de)	2001-10-12	2003-04-17	Probiodrug Ag	Peptidylketone als Inhibitoren der DPIV
US6709651B2 (en) *	2001-07-03	2004-03-23	B.M.R.A. Corporation B.V.	Treatment of substance P-related disorders
US20030165954A1 (en) *	2002-01-09	2003-09-04	Third Wave Technologies, Inc.	Cancer profiles
AU2002331226A1 (en)	2002-08-09	2004-03-11	Prosidion Ltd.	Methods for improving islet signaling in diabetes mellitus and for its prevention
US20040242568A1 (en)	2003-03-25	2004-12-02	Syrrx, Inc.	Dipeptidyl peptidase inhibitors
EP1625122A1 (en)	2003-05-14	2006-02-15	Takeda San Diego, Inc.	Dipeptidyl peptidase inhibitors
US7678909B1 (en)	2003-08-13	2010-03-16	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
MXPA06001601A (es)	2003-08-13	2006-08-25	Takeda Pharmaceutical	Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa.
US7169926B1 (en)	2003-08-13	2007-01-30	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
EP1699777B1 (en)	2003-09-08	2012-12-12	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
US7732446B1 (en)	2004-03-11	2010-06-08	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
EA013427B1 (ru)	2004-03-15	2010-04-30	Такеда Фармасьютикал Компани Лимитед	Ингибиторы дипептидилпептидазы
WO2005106021A1 (en) *	2004-04-28	2005-11-10	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 8 (dpp8)
EP1745293A1 (en) *	2004-04-28	2007-01-24	Bayer HealthCare AG	Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 9 (dpp9)
US7687638B2 (en)	2004-06-04	2010-03-30	Takeda San Diego, Inc.	Dipeptidyl peptidase inhibitors
WO2006019965A2 (en)	2004-07-16	2006-02-23	Takeda San Diego, Inc.	Dipeptidyl peptidase inhibitors
US20060063719A1 (en) *	2004-09-21	2006-03-23	Point Therapeutics, Inc.	Methods for treating diabetes
WO2006068978A2 (en) *	2004-12-21	2006-06-29	Takeda Pharmaceutial Company Limited	Dipeptidyl peptidase inhibitors
PE20070622A1 (es) *	2005-09-14	2007-08-22	Takeda Pharmaceutical	Administracion de inhibidores de dipeptidil peptidasa
AU2006290205B2 (en)	2005-09-14	2012-12-13	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors for treating diabetes
WO2007035629A2 (en)	2005-09-16	2007-03-29	Takeda Pharmaceutical Company Limited	Process for the preparation of pyrimidinedione derivatives
JP5242402B2 (ja) *	2005-10-11	2013-07-24	アマノエンザイムユーエスエーカンパニー，リミテッド	Ｐａｉ−１の酵素阻害物質
WO2007054577A1 (en)	2005-11-14	2007-05-18	Probiodrug Ag	Cyclopropyl-fused pyrrolidine derivatives as dipeptidyl peptidase iv inhibitors
WO2007112347A1 (en)	2006-03-28	2007-10-04	Takeda Pharmaceutical Company Limited	Dipeptidyl peptidase inhibitors
WO2007116092A1 (en)	2006-04-12	2007-10-18	Probiodrug Ag	Enzyme inhibitors
US8324383B2 (en)	2006-09-13	2012-12-04	Takeda Pharmaceutical Company Limited	Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en)	2006-11-29	2008-10-01	Takeda Pharmaceutical	Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
CN101259119B (zh) *	2007-03-08	2010-05-19	上海市计划生育科学研究所	一种丝氨酸蛋白酶抑制剂及其衍生物在生育调节中的应用
US8093236B2 (en)	2007-03-13	2012-01-10	Takeda Pharmaceuticals Company Limited	Weekly administration of dipeptidyl peptidase inhibitors
US9593148B2 (en) *	2012-11-02	2017-03-14	Georg-August-Universitat Gottingen Stiftung Offentlichen Rechts	DPP8 and DPP9 peptide inhibitors
CN113993997A (zh) *	2019-03-26	2022-01-28	Encodia 公司	修饰的切割酶，及其使用和相关试剂盒
US11427814B2 (en)	2019-03-26	2022-08-30	Encodia, Inc.	Modified cleavases, uses thereof and related kits

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6291662B1 (en)	1984-12-05	2001-09-18	Amgen Inc.	Recombinant methods for production of serine protease inhibitors and DNA sequences
IL111785A0 (en)	1993-12-03	1995-01-24	Ferring Bv	Dp-iv inhibitors and pharmaceutical compositions containing them
JP2003532372A (ja)	1999-01-11	2003-11-05	インサイト・ファーマスーティカルズ・インコーポレイテッド	ヒトペプチダーゼ
EP1165784A2 (en) *	1999-03-31	2002-01-02	Curagen Corporation	Nucleic acids including open reading frames encoding polypeptides; "orfx"
DE60029230T2 (de) *	1999-09-10	2007-06-06	The University Of Sydney, Sydney	Dipeptidyl-peptidasen
CN1307128A (zh)	2000-01-26	2001-08-08	上海博道基因技术有限公司	一种新的多肽——人二肽氨肽酶28和编码这种多肽的多核苷酸
JP2004515217A (ja) *	2000-06-16	2004-05-27	インサイト・ゲノミックス・インコーポレイテッド	プロテアーゼ

2001
- 2001-10-12 CA CA002425001A patent/CA2425001A1/en not_active Abandoned
- 2001-10-12 CN CNB018173128A patent/CN100354417C/zh not_active Expired - Fee Related
- 2001-10-12 IL IL15524501A patent/IL155245A0/xx unknown
- 2001-10-12 PL PL01366005A patent/PL366005A1/xx unknown
- 2001-10-12 US US09/976,674 patent/US6844180B2/en not_active Expired - Fee Related
- 2001-10-12 RU RU2003112700/13A patent/RU2305133C2/ru not_active IP Right Cessation
- 2001-10-12 NZ NZ525443A patent/NZ525443A/en unknown
- 2001-10-12 HU HU0301356A patent/HUP0301356A3/hu unknown
- 2001-10-12 CN CNA2007101850111A patent/CN101270362A/zh active Pending
- 2001-10-12 AU AU2002213138A patent/AU2002213138B2/en not_active Ceased
- 2001-10-12 CZ CZ20031301A patent/CZ20031301A3/cs unknown
- 2001-10-12 AU AU1313802A patent/AU1313802A/xx active Pending
- 2001-10-12 KR KR1020037005169A patent/KR100875221B1/ko not_active IP Right Cessation
- 2001-10-12 MX MXPA03003191A patent/MXPA03003191A/es active IP Right Grant
- 2001-10-12 EP EP01981501A patent/EP1346033A2/en not_active Ceased
- 2001-10-12 WO PCT/US2001/031874 patent/WO2002031134A2/en active IP Right Grant
- 2001-10-12 JP JP2002534503A patent/JP2004528812A/ja active Pending
2003
- 2003-04-03 IL IL155245A patent/IL155245A/en not_active IP Right Cessation
- 2003-04-11 NO NO20031702A patent/NO329842B1/no not_active IP Right Cessation
- 2003-04-29 ZA ZA200303306A patent/ZA200303306B/en unknown
2004
- 2004-11-05 US US10/982,512 patent/US7157241B2/en not_active Expired - Fee Related
2005
- 2005-11-09 HK HK05109986A patent/HK1078104A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU1313802A (en)	2002-04-22
NZ525443A (en)	2006-04-28
NO20031702D0 (no)	2003-04-11
MXPA03003191A (es)	2004-12-03
KR100875221B1 (ko)	2008-12-19
RU2305133C2 (ru)	2007-08-27
NO329842B1 (no)	2011-01-10
WO2002031134A2 (en)	2002-04-18
US7157241B2 (en)	2007-01-02
CN101270362A (zh)	2008-09-24
US20020115843A1 (en)	2002-08-22
CN1636061A (zh)	2005-07-06
IL155245A (en)	2010-04-15
US6844180B2 (en)	2005-01-18
CA2425001A1 (en)	2002-04-18
EP1346033A2 (en)	2003-09-24
US20050059081A1 (en)	2005-03-17
NO20031702L (no)	2003-05-15
HUP0301356A2 (hu)	2003-10-28
CN100354417C (zh)	2007-12-12
PL366005A1 (en)	2005-01-24
ZA200303306B (en)	2004-08-12
HUP0301356A3 (en)	2010-03-29
KR20030038815A (ko)	2003-05-16
WO2002031134A3 (en)	2003-07-17
CZ20031301A3 (cs)	2003-10-15
AU2002213138B2 (en)	2006-07-20
JP2004528812A (ja)	2004-09-24
IL155245A0 (en)	2003-11-23

Legal Events

Date	Code	Title	Description
2008-06-27	CHRG	Changes in the register	Free format text: CORRECTION OF THE NAME OF THE INVENTOR
2012-05-18	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20111012

Publication	Publication Date	Title
HK1078104A1 (en)	2006-03-03	Novel serine protease genes related to dppiv
AU7961401A (en)	2002-03-04	Subtilase enzymes
HK1062676A1 (en)	2004-11-19	Biaryl compounds as serine protease inhibitors
AU2001271427A1 (en)	2002-01-08	Novel proteases
GB0017387D0 (en)	2000-08-30	Novel enzyme
ZA992447B (en)	2000-10-10	Quinoxalinones as serine protease inhibitors.
ZA992448B (en)	2000-10-11	Quinoxalinones as serine protease inhibitors.
HUP0301795A3 (en)	2006-11-28	Dna encoding human serine protease d-g
EP1179052A4 (en)	2004-12-15	SERINE PROTEASES
AU2002210379A1 (en)	2002-04-22	Subtilase variants
GB2364338B (en)	2004-01-28	Improvements relating to construction
EP1132473A4 (en)	2002-06-12	NEW SERINE PROTEASE BSSP6
EP1544304A4 (en)	2006-05-10	NEW SERINPROTEASE
AU5748800A (en)	2001-02-19	Serine proteases
GB2359653B (en)	2004-05-26	Improvements relating to entertainment machines
GB2367065A8 (en)	2002-03-27	Enzyme-containing laundry booster compositions
GB0312209D0 (en)	2003-07-02	Improvements relating to signal mixers
AU2001278787A1 (en)	2002-03-04	Novel protease gene
GB2385476B (en)	2004-11-24	Improvements relating to signal mixers
AU2002219516A1 (en)	2002-07-08	Novel protease
GB0000427D0 (en)	2000-03-01	Improvements relating to games
GB0025715D0 (en)	2000-12-06	Improvements relating to haribrushes
GB0022811D0 (en)	2000-11-01	Improvements relating to supports
GB0002453D0 (en)	2000-03-22	Improvements relating to display means
AU2002226699A1 (en)	2002-08-06	Novel serine protease mp493