HK1076128A1 - Humanized collagen antibodies and related methods - Google Patents
Humanized collagen antibodies and related methodsInfo
- Publication number
- HK1076128A1 HK1076128A1 HK05108059.6A HK05108059A HK1076128A1 HK 1076128 A1 HK1076128 A1 HK 1076128A1 HK 05108059 A HK05108059 A HK 05108059A HK 1076128 A1 HK1076128 A1 HK 1076128A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- related methods
- collagen antibodies
- cdrs
- specific binding
- binding activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6843—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/995,529 US7365167B2 (en) | 2001-11-26 | 2001-11-26 | Humanized collagen antibodies and related methods |
US10/011,250 US7390885B2 (en) | 2001-11-26 | 2001-12-06 | Humanized collagen antibodies and related methods |
PCT/US2002/038147 WO2003046204A2 (en) | 2001-11-26 | 2002-11-26 | Humanized collagen antibodies and related methods |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1076128A1 true HK1076128A1 (en) | 2006-01-06 |
Family
ID=26682164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05108059.6A HK1076128A1 (en) | 2001-11-26 | 2005-09-15 | Humanized collagen antibodies and related methods |
Country Status (12)
Country | Link |
---|---|
US (4) | US7390885B2 (zh) |
EP (1) | EP1478764B1 (zh) |
JP (2) | JP4519464B2 (zh) |
CN (1) | CN1596313B (zh) |
AT (1) | ATE509955T1 (zh) |
AU (1) | AU2009200070A1 (zh) |
CA (1) | CA2468016A1 (zh) |
HK (1) | HK1076128A1 (zh) |
IL (1) | IL162117A0 (zh) |
MX (1) | MXPA04004857A (zh) |
NZ (1) | NZ533408A (zh) |
WO (1) | WO2003046204A2 (zh) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
US7365167B2 (en) | 2001-11-26 | 2008-04-29 | Cell Matrix, Inc. | Humanized collagen antibodies and related methods |
US7541440B2 (en) * | 2002-09-30 | 2009-06-02 | Immunomedics, Inc. | Chimeric, human and humanized anti-granulocyte antibodies and methods of use |
EP2168986A3 (en) | 2004-02-19 | 2010-07-28 | Genentech, Inc. | CDR-repaired antibodies |
AU2006283174A1 (en) * | 2005-08-24 | 2007-03-01 | Cell-Matrix, Inc. | Combination therapies for inhibiting integrin-extracellular matrix interactions |
WO2007146401A2 (en) * | 2006-06-14 | 2007-12-21 | Cell-Matrix, Inc. | Denatured collagen peptides and uses thereof |
NO346945B1 (no) * | 2006-06-30 | 2023-03-13 | Novo Nordisk As | Anti-NKG2A-antistoffer og anvendelser derav |
PL2099826T3 (pl) * | 2007-01-05 | 2014-04-30 | Univ Zuerich | Przeciwciało przeciwko beta-amyloidowi i jego zastosowania |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
PT2238166E (pt) | 2007-10-05 | 2014-02-11 | Genentech Inc | Utilização do anticorpo anti-amilóide beta em doenças oculares |
JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
EP2359852A4 (en) * | 2008-11-17 | 2015-05-20 | Nat Cancer Ct | NEW CANCERED THERAPY WITH A SUBSTANCE COMPLEX SPECIFICALLY BINDING TO A TUMOR STREAM FACTOR AND ANTITUMIR COMPOUND |
EP2770327B1 (en) * | 2009-03-30 | 2017-06-14 | Nordic Bioscience A/S | Fibrosis biomarker assay |
US20120237504A1 (en) * | 2009-10-20 | 2012-09-20 | Maine Medical Center | Compositions and methods for treating inflammation and fibrosis |
EP2544694B1 (en) * | 2010-03-02 | 2018-10-31 | Novelmed Therapeutics, Inc. | A method for inhibiting alternative pathway mediated disorders with anti-properdin antibodies that inhibit c5 interactions with properdin |
RU2607368C2 (ru) | 2010-07-30 | 2017-01-10 | Ац Иммуне С.А. | Безопасные и функциональные гуманизированные антитела |
EP2639243A4 (en) * | 2010-11-10 | 2014-06-04 | Nippon Kayaku Kk | ANTIBODIES AGAINST UNIVERSAL TYPE IV COLLAGEN POLYPEPTIDE AND PHARMACEUTICAL OR ACTIVE SUBSTANCE FOR THE DIAGNOSIS, PREVENTION OR TREATMENT OF TUMORS THEREOF |
AU2012311286B2 (en) * | 2011-09-19 | 2018-07-26 | Kymab Limited | Antibodies, variable domains and chains tailored for human use |
USRE49477E1 (en) | 2012-04-20 | 2023-03-28 | Thomas Jefferson University | Engineered antibody for inhibition of fibrosis |
US9926366B2 (en) | 2012-10-04 | 2018-03-27 | Novelmed Therapeutics, Inc. | Methods of treating a hemolytic disorder comprising administering anti-properdin antibodies |
CN105209493B (zh) | 2013-03-14 | 2019-05-03 | 德克萨斯州大学***董事会 | 用于诊断和治疗用途的her3特异性单克隆抗体 |
AU2017330346A1 (en) | 2016-09-21 | 2019-02-21 | Nextcure, Inc. | Antibodies for Siglec-15 and methods of use thereof |
WO2020081714A1 (en) * | 2018-10-16 | 2020-04-23 | Board Of Regents, The University Of Texas System | Identification and targeting of pathogenic extracellular matrix for diagnosis and treatment of cancer and other diseases |
US20220010018A1 (en) * | 2018-11-16 | 2022-01-13 | Albert Einstein College Of Medicine | MONOCLONAL ANTIBODIES AGAINST IgV DOMAIN OF B7-H3 AND USES THEREOF |
MX2021008760A (es) * | 2019-01-28 | 2021-08-24 | Tuojie Biotech Shanghai Co Ltd | Anticuerpo anti-cd79b, fragmento de union a antigeno del mismo y uso farmaceutico del mismo. |
WO2021252974A2 (en) * | 2020-06-11 | 2021-12-16 | Proviva Therapeutics (Hong Kong) Limited | Collagen-targeted fusion proteins and antibodies |
WO2022147298A1 (en) * | 2020-12-31 | 2022-07-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Vascular-endothelial cadherin activating antibodies and uses thereof |
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-
2001
- 2001-12-06 US US10/011,250 patent/US7390885B2/en not_active Expired - Fee Related
-
2002
- 2002-11-26 NZ NZ533408A patent/NZ533408A/en not_active IP Right Cessation
- 2002-11-26 CN CN028264126A patent/CN1596313B/zh not_active Expired - Fee Related
- 2002-11-26 CA CA002468016A patent/CA2468016A1/en not_active Abandoned
- 2002-11-26 EP EP02795695A patent/EP1478764B1/en not_active Expired - Lifetime
- 2002-11-26 MX MXPA04004857A patent/MXPA04004857A/es not_active Application Discontinuation
- 2002-11-26 JP JP2003547635A patent/JP4519464B2/ja not_active Expired - Fee Related
- 2002-11-26 WO PCT/US2002/038147 patent/WO2003046204A2/en active Search and Examination
- 2002-11-26 AT AT02795695T patent/ATE509955T1/de not_active IP Right Cessation
- 2002-11-26 IL IL16211702A patent/IL162117A0/xx unknown
-
2005
- 2005-09-15 HK HK05108059.6A patent/HK1076128A1/xx not_active IP Right Cessation
-
2006
- 2006-07-14 US US11/486,894 patent/US7566770B2/en not_active Expired - Fee Related
-
2008
- 2008-05-08 US US12/117,642 patent/US7763248B2/en not_active Expired - Fee Related
-
2009
- 2009-01-08 AU AU2009200070A patent/AU2009200070A1/en not_active Abandoned
- 2009-07-15 JP JP2009167279A patent/JP2009240324A/ja not_active Withdrawn
-
2010
- 2010-06-10 US US12/813,352 patent/US20100303726A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003046204A3 (en) | 2004-09-23 |
EP1478764B1 (en) | 2011-05-18 |
ATE509955T1 (de) | 2011-06-15 |
JP4519464B2 (ja) | 2010-08-04 |
MXPA04004857A (es) | 2005-04-11 |
CN1596313B (zh) | 2010-05-26 |
US20080050388A1 (en) | 2008-02-28 |
JP2005510246A (ja) | 2005-04-21 |
US20070077199A1 (en) | 2007-04-05 |
EP1478764A4 (en) | 2007-05-23 |
WO2003046204A2 (en) | 2003-06-05 |
US7390885B2 (en) | 2008-06-24 |
AU2002360439A2 (en) | 2003-06-10 |
AU2002360439A1 (en) | 2003-06-10 |
US7763248B2 (en) | 2010-07-27 |
US20100303726A1 (en) | 2010-12-02 |
IL162117A0 (en) | 2005-11-20 |
WO2003046204A8 (en) | 2004-07-08 |
NZ533408A (en) | 2006-06-30 |
CA2468016A1 (en) | 2003-06-05 |
US20080260733A1 (en) | 2008-10-23 |
JP2009240324A (ja) | 2009-10-22 |
CN1596313A (zh) | 2005-03-16 |
US7566770B2 (en) | 2009-07-28 |
AU2009200070A1 (en) | 2009-02-05 |
EP1478764A2 (en) | 2004-11-24 |
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