HK1049157A1 - 具有螺接的三環化合物 - Google Patents
具有螺接的三環化合物Info
- Publication number
- HK1049157A1 HK1049157A1 HK03100716.0A HK03100716A HK1049157A1 HK 1049157 A1 HK1049157 A1 HK 1049157A1 HK 03100716 A HK03100716 A HK 03100716A HK 1049157 A1 HK1049157 A1 HK 1049157A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- spiro union
- tricyclic compounds
- useful
- relates
- inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96444—Factor X (3.4.21.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Prostheses (AREA)
- External Artificial Organs (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22288399 | 1999-06-30 | ||
PCT/JP2000/004374 WO2001002397A1 (fr) | 1999-06-30 | 2000-06-30 | Composes tricycliques presentant une jonction spiro |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1049157A1 true HK1049157A1 (zh) | 2003-05-02 |
Family
ID=16789385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03100716.0A HK1049157A1 (zh) | 1999-06-30 | 2003-01-28 | 具有螺接的三環化合物 |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1191028B1 (zh) |
JP (1) | JP4890707B2 (zh) |
KR (1) | KR20020015061A (zh) |
CN (1) | CN1371375A (zh) |
AT (1) | ATE281457T1 (zh) |
AU (1) | AU774397B2 (zh) |
BR (1) | BR0012093A (zh) |
CA (1) | CA2380852C (zh) |
CZ (1) | CZ20014696A3 (zh) |
DE (1) | DE60015541T2 (zh) |
HK (1) | HK1049157A1 (zh) |
HU (1) | HUP0202188A3 (zh) |
IL (1) | IL147348A0 (zh) |
MX (1) | MXPA02000003A (zh) |
NO (1) | NO20016402L (zh) |
NZ (1) | NZ516363A (zh) |
PL (1) | PL352862A1 (zh) |
SK (1) | SK19292001A3 (zh) |
TR (1) | TR200103853T2 (zh) |
WO (1) | WO2001002397A1 (zh) |
ZA (1) | ZA200110558B (zh) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2416384A1 (en) * | 2000-07-17 | 2003-01-16 | Takeda Chemical Industries, Ltd. | Sulfone derivatives, their production and use |
EP1346994A4 (en) * | 2000-12-28 | 2005-01-19 | Mochida Pharm Co Ltd | INHIBITORS OF THE CHOLESTEROL BIOSYNTHESIS CONTAINING TRICYCLIC SPIRO COMPOUNDS AS AN ACTIVE SUBSTANCE |
CN100513398C (zh) | 2002-12-03 | 2009-07-15 | Axys药物公司 | 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物 |
TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
WO2006006490A1 (ja) * | 2004-07-08 | 2006-01-19 | Ono Pharmaceutical Co., Ltd. | スピロ化合物 |
CA2602025A1 (en) | 2005-03-31 | 2006-10-12 | Mochida Pharmaceutical Co., Ltd. | Tricyclic spiro compound comprising acyl group bound to nitrogen atom in the ring |
EP2020411A4 (en) | 2006-05-23 | 2010-08-04 | Mochida Pharm Co Ltd | TETRACYCLIC SPIRO COMPOUND |
US7739434B2 (en) | 2008-01-11 | 2010-06-15 | International Business Machines Corporation | Performing a configuration virtual topology change and instruction therefore |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3855147D1 (de) * | 1987-07-20 | 1996-05-02 | Duphar Int Res | 8,9-Anellierte 1,2,3,4-Tetrahydro-beta-carbolin-Derivate |
US5292747A (en) * | 1990-08-07 | 1994-03-08 | Hoffman-La Roche Inc. | Substituted pyrroles |
-
2000
- 2000-06-30 WO PCT/JP2000/004374 patent/WO2001002397A1/ja not_active Application Discontinuation
- 2000-06-30 AT AT00940912T patent/ATE281457T1/de not_active IP Right Cessation
- 2000-06-30 EP EP00940912A patent/EP1191028B1/en not_active Expired - Lifetime
- 2000-06-30 SK SK1929-2001A patent/SK19292001A3/sk unknown
- 2000-06-30 CN CN00811976A patent/CN1371375A/zh active Pending
- 2000-06-30 JP JP2001507834A patent/JP4890707B2/ja not_active Expired - Fee Related
- 2000-06-30 BR BR0012093-6A patent/BR0012093A/pt not_active IP Right Cessation
- 2000-06-30 KR KR1020017016658A patent/KR20020015061A/ko not_active Application Discontinuation
- 2000-06-30 TR TR2001/03853T patent/TR200103853T2/xx unknown
- 2000-06-30 MX MXPA02000003A patent/MXPA02000003A/es unknown
- 2000-06-30 NZ NZ516363A patent/NZ516363A/en unknown
- 2000-06-30 HU HU0202188A patent/HUP0202188A3/hu unknown
- 2000-06-30 IL IL14734800A patent/IL147348A0/xx unknown
- 2000-06-30 DE DE60015541T patent/DE60015541T2/de not_active Expired - Lifetime
- 2000-06-30 CZ CZ20014696A patent/CZ20014696A3/cs unknown
- 2000-06-30 PL PL00352862A patent/PL352862A1/xx not_active Application Discontinuation
- 2000-06-30 AU AU55720/00A patent/AU774397B2/en not_active Ceased
- 2000-06-30 CA CA002380852A patent/CA2380852C/en not_active Expired - Fee Related
-
2001
- 2001-12-21 ZA ZA200110558A patent/ZA200110558B/en unknown
- 2001-12-28 NO NO20016402A patent/NO20016402L/no not_active Application Discontinuation
-
2003
- 2003-01-28 HK HK03100716.0A patent/HK1049157A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
DE60015541T2 (de) | 2005-12-08 |
AU5572000A (en) | 2001-01-22 |
HUP0202188A2 (en) | 2002-10-28 |
CZ20014696A3 (cs) | 2002-05-15 |
HUP0202188A3 (en) | 2004-04-28 |
NZ516363A (en) | 2004-05-28 |
NO20016402L (no) | 2002-02-27 |
EP1191028A4 (en) | 2002-10-23 |
KR20020015061A (ko) | 2002-02-27 |
WO2001002397A1 (fr) | 2001-01-11 |
IL147348A0 (en) | 2002-08-14 |
AU774397B2 (en) | 2004-06-24 |
BR0012093A (pt) | 2002-07-16 |
CN1371375A (zh) | 2002-09-25 |
CA2380852C (en) | 2009-10-20 |
ZA200110558B (en) | 2002-09-12 |
CA2380852A1 (en) | 2001-01-11 |
JP4890707B2 (ja) | 2012-03-07 |
EP1191028B1 (en) | 2004-11-03 |
DE60015541D1 (de) | 2004-12-09 |
MXPA02000003A (es) | 2003-07-21 |
ATE281457T1 (de) | 2004-11-15 |
SK19292001A3 (sk) | 2002-06-04 |
PL352862A1 (en) | 2003-09-08 |
EP1191028A1 (en) | 2002-03-27 |
TR200103853T2 (tr) | 2002-11-21 |
NO20016402D0 (no) | 2001-12-28 |
WO2001002397A9 (fr) | 2001-04-05 |
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