HK1048314A1 - 2-arylimino-2,3-dihydrothiazoles, and their use thereof as somatostatin receptor ligands - Google Patents

2-arylimino-2,3-dihydrothiazoles, and their use thereof as somatostatin receptor ligands

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Publication number
HK1048314A1
HK1048314A1 HK03100526.0A HK03100526A HK1048314A1 HK 1048314 A1 HK1048314 A1 HK 1048314A1 HK 03100526 A HK03100526 A HK 03100526A HK 1048314 A1 HK1048314 A1 HK 1048314A1
Authority
HK
Hong Kong
Prior art keywords
dihydrothiazoles
arylimino
receptor ligands
somatostatin receptor
somatostatin
Prior art date
Application number
HK03100526.0A
Other languages
English (en)
Inventor
Christophe Moinet
Carole Sackur
Christophe Thurieau
Original Assignee
Ipsen Pharma Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma Sas filed Critical Ipsen Pharma Sas
Publication of HK1048314A1 publication Critical patent/HK1048314A1/xx

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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Diabetes (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
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  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
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HK03100526.0A 1999-07-22 2003-01-22 2-arylimino-2,3-dihydrothiazoles, and their use thereof as somatostatin receptor ligands HK1048314A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9909496A FR2796643B1 (fr) 1999-07-22 1999-07-22 Derives de 2-arylimino-2, 3-dihydrothiazoles, leurs procedes de preparation et leur utilisation therapeutique
PCT/FR2000/002095 WO2001007424A1 (fr) 1999-07-22 2000-07-21 2-arylimino-2,3-dihydrothiazoles et leur utilisation comme ligands des recepteurs de la somatostatine

Publications (1)

Publication Number Publication Date
HK1048314A1 true HK1048314A1 (en) 2003-03-28

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HK03100526.0A HK1048314A1 (en) 1999-07-22 2003-01-22 2-arylimino-2,3-dihydrothiazoles, and their use thereof as somatostatin receptor ligands

Country Status (20)

Country Link
US (1) US6727269B1 (ru)
EP (1) EP1202980A1 (ru)
JP (2) JP4063537B2 (ru)
KR (1) KR100692352B1 (ru)
CN (1) CN100443479C (ru)
AR (1) AR035321A1 (ru)
AU (1) AU782187B2 (ru)
BR (1) BR0012647A (ru)
CA (1) CA2382940C (ru)
CZ (1) CZ302073B6 (ru)
FR (1) FR2796643B1 (ru)
HK (1) HK1048314A1 (ru)
HU (1) HUP0202425A3 (ru)
IL (3) IL147582A0 (ru)
MX (1) MXPA02000723A (ru)
NO (1) NO322394B1 (ru)
NZ (1) NZ516599A (ru)
PL (1) PL353831A1 (ru)
RU (1) RU2266287C2 (ru)
WO (1) WO2001007424A1 (ru)

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ES2336425T3 (es) 2000-06-30 2010-04-13 Dainippon Sumitomo Pharma Co., Ltd. Derivados de tiazoles utiles como agentes antiinflamatorios.
DE10133665A1 (de) * 2001-07-11 2003-01-30 Boehringer Ingelheim Pharma Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
WO2003057214A1 (en) 2001-12-28 2003-07-17 Somatocor Pharmaceuticals, Inc. Imidazolidin-2,4-dione derivatives as non-peptide somatostatin receptor ligands
US7067538B2 (en) 2002-08-09 2006-06-27 Warner-Lambert Company, Llc MCP-1 receptor antagonists and methods of use thereof
JP4896387B2 (ja) * 2003-09-30 2012-03-14 武田薬品工業株式会社 チアゾリン誘導体およびその用途
US7534887B2 (en) 2003-09-30 2009-05-19 Takeda Pharmaceutical Company Limited Thiazoline derivative and use of the same
WO2005082845A1 (en) * 2004-02-27 2005-09-09 Oy Juvantia Pharma Ltd Novel therapies with somatostatin receptor agonists
WO2005082844A1 (en) * 2004-02-27 2005-09-09 Oy Juvantia Pharma Ltd Treatment of diseases by using a somatostatin receptor agonist
UA86053C2 (ru) 2004-03-15 2009-03-25 Янссен Фармацевтика Н.В. Соединения как модуляторы опиоидных рецепторов
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WO2006032273A1 (en) * 2004-09-22 2006-03-30 H. Lundbeck A/S 2-acylaminothiazole derivatives
US7674912B2 (en) * 2005-04-25 2010-03-09 H. Lundbeck A/S Pro-drugs of N-thiazol-2-yl-benzamide derivatives
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JP4063537B2 (ja) 2008-03-19
CN100443479C (zh) 2008-12-17
CN1362952A (zh) 2002-08-07
BR0012647A (pt) 2002-04-09
AU782187B2 (en) 2005-07-07
CZ302073B6 (cs) 2010-09-29
RU2266287C2 (ru) 2005-12-20
CA2382940C (fr) 2010-08-17
WO2001007424A1 (fr) 2001-02-01
IL147582A0 (en) 2002-08-14
KR20020088405A (ko) 2002-11-27
FR2796643B1 (fr) 2005-04-29
HUP0202425A3 (en) 2002-12-28
RU2002104574A (ru) 2004-01-20
EP1202980A1 (fr) 2002-05-08
JP2006257093A (ja) 2006-09-28
FR2796643A1 (fr) 2001-01-26
CA2382940A1 (fr) 2001-02-01
IL147582A (en) 2009-08-03
NZ516599A (en) 2004-01-30
KR100692352B1 (ko) 2007-03-12
AR035321A1 (es) 2004-05-12
IL185786A0 (en) 2008-01-06
JP2003505453A (ja) 2003-02-12
PL353831A1 (en) 2003-12-01
US6727269B1 (en) 2004-04-27
AU7005300A (en) 2001-02-13
NO322394B1 (no) 2006-10-02
CZ2002187A3 (cs) 2002-06-12

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