HK1016067A1 - Topical bisphosphonates for prevention of bone resorption - Google Patents

Topical bisphosphonates for prevention of bone resorption

Info

Publication number
HK1016067A1
HK1016067A1 HK99101081A HK99101081A HK1016067A1 HK 1016067 A1 HK1016067 A1 HK 1016067A1 HK 99101081 A HK99101081 A HK 99101081A HK 99101081 A HK99101081 A HK 99101081A HK 1016067 A1 HK1016067 A1 HK 1016067A1
Authority
HK
Hong Kong
Prior art keywords
bisphosphonates
bone resorption
topical
prevention
bone
Prior art date
Application number
HK99101081A
Other languages
English (en)
Inventor
Itzhak Binderman
Avinoam Yaffe
Original Assignee
Itzhak Binderman
Avinoam Yaffe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603125.7A external-priority patent/GB9603125D0/en
Application filed by Itzhak Binderman, Avinoam Yaffe filed Critical Itzhak Binderman
Publication of HK1016067A1 publication Critical patent/HK1016067A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK99101081A 1996-02-14 1999-03-16 Topical bisphosphonates for prevention of bone resorption HK1016067A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1163296P 1996-02-14 1996-02-14
GBGB9603125.7A GB9603125D0 (en) 1996-02-15 1996-02-15 Topical bisphosphonates for prevention of bone resorption
PCT/IL1997/000050 WO1997029754A1 (en) 1996-02-14 1997-02-12 Topical bisphosphonates for prevention of bone resorption

Publications (1)

Publication Number Publication Date
HK1016067A1 true HK1016067A1 (en) 1999-10-29

Family

ID=26308705

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99101081A HK1016067A1 (en) 1996-02-14 1999-03-16 Topical bisphosphonates for prevention of bone resorption

Country Status (9)

Country Link
EP (1) EP0886521B1 (xx)
JP (1) JP2000504718A (xx)
AT (1) ATE240737T1 (xx)
AU (1) AU723516B2 (xx)
CA (1) CA2245793A1 (xx)
DE (1) DE69722190T2 (xx)
ES (1) ES2197329T3 (xx)
HK (1) HK1016067A1 (xx)
WO (1) WO1997029754A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0824341A4 (en) * 1995-05-12 1999-07-07 Merck & Co Inc PREVENTING TOOTH LOSS THROUGH ADMINISTRATION OF ALENDRONATE OR ITS SALTS
CN1191833C (zh) 1999-11-25 2005-03-09 山之内制药株式会社 牙周病治疗药
US6410520B2 (en) 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
WO2002004038A1 (en) * 2000-07-12 2002-01-17 Hopital Orthopedique De La Suisse Romande Active biocoating for bone implant
EP2055297A1 (en) * 2007-11-05 2009-05-06 Merz Pharma GmbH & Co. KGaA Therapy option for recoloration of hair via bisphosphonates by physiological repigmentation with age-related and/or premature "grayed" patients

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74617A (en) * 1985-03-15 1988-11-15 Yeda Res & Dev Compositions comprising a vitamin d derivative and method for the local treatment of bone fractures in animals
US5002769A (en) * 1987-03-13 1991-03-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions for the sustained-release of chlorhexidine
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
JP3411690B2 (ja) * 1994-09-21 2003-06-03 帝人株式会社 局所投与用アレンドロン酸ナトリウム製剤

Also Published As

Publication number Publication date
DE69722190T2 (de) 2004-05-27
AU723516B2 (en) 2000-08-31
ATE240737T1 (de) 2003-06-15
EP0886521B1 (en) 2003-05-21
EP0886521A1 (en) 1998-12-30
AU1616197A (en) 1997-09-02
DE69722190D1 (de) 2003-06-26
ES2197329T3 (es) 2004-01-01
WO1997029754A1 (en) 1997-08-21
JP2000504718A (ja) 2000-04-18
CA2245793A1 (en) 1997-08-21

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070212