GT200500357A - Indazoles substituidos, composicones que los comprenden, procedimiento de su preparacion y utilizacion - Google Patents

Indazoles substituidos, composicones que los comprenden, procedimiento de su preparacion y utilizacion

Info

Publication number
GT200500357A
GT200500357A GT200500357A GT200500357A GT200500357A GT 200500357 A GT200500357 A GT 200500357A GT 200500357 A GT200500357 A GT 200500357A GT 200500357 A GT200500357 A GT 200500357A GT 200500357 A GT200500357 A GT 200500357A
Authority
GT
Guatemala
Prior art keywords
preparation
procedure
substituted
compositions
indazols
Prior art date
Application number
GT200500357A
Other languages
English (en)
Inventor
Halley Franck
Souaille Catherine
Tabart Michael
Bacque Eric
Viviani Fabrice
Ronan Baptiste
Letallec Jean-Philippe
Filoche-Romme Bruno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34954266&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT200500357(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT200500357A publication Critical patent/GT200500357A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A LA PREPARACIÓN DE INDOLES SUSTITUIDOS, A LAS COMPOSICIONES QUE LOS CONTIENEN, A SU PROCEDIMIENTO DE PREPARACIÓN Y A SU UTILIZACIÓN COMO MEDICAMENTOS, EN PARTICULAR COMO AGENTES ANTICANCEROSOS.
GT200500357A 2004-12-06 2005-12-06 Indazoles substituidos, composicones que los comprenden, procedimiento de su preparacion y utilizacion GT200500357A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0412966A FR2878849B1 (fr) 2004-12-06 2004-12-06 Indoles substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
GT200500357A true GT200500357A (es) 2007-01-09

Family

ID=34954266

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200500357A GT200500357A (es) 2004-12-06 2005-12-06 Indazoles substituidos, composicones que los comprenden, procedimiento de su preparacion y utilizacion

Country Status (14)

Country Link
US (1) US7566736B2 (es)
EP (1) EP1841762A1 (es)
CN (1) CN101098868A (es)
AR (1) AR052257A1 (es)
AU (1) AU2005313253A1 (es)
CA (1) CA2586991A1 (es)
FR (1) FR2878849B1 (es)
GT (1) GT200500357A (es)
PA (1) PA8654701A1 (es)
SV (1) SV2006002319A (es)
TN (1) TNSN07167A1 (es)
TW (1) TW200634007A (es)
UY (1) UY29248A1 (es)
WO (1) WO2006061493A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2884821B1 (fr) * 2005-04-26 2007-07-06 Aventis Pharma Sa Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
DE102005037499A1 (de) * 2005-08-09 2007-02-15 Merck Patent Gmbh Pyrazolderivate
WO2007090141A2 (en) * 2006-02-01 2007-08-09 Smithkline Beecham Corporation Pyrrolo [2, 3, b] pyridine derivatives useful as raf kinase inhibitors
US7838542B2 (en) * 2006-06-29 2010-11-23 Kinex Pharmaceuticals, Llc Bicyclic compositions and methods for modulating a kinase cascade
PL2134685T3 (pl) 2007-04-16 2016-02-29 Abbvie Inc Pochodne indolu niepodstawione w pozycji 7 jako inhibitory Mcl-1
CN102532042A (zh) * 2010-12-30 2012-07-04 上海医药工业研究院 一种芳基脲类化合物、其中间体及其应用
UY34893A (es) 2012-07-10 2014-02-28 Takeda Pharmaceutical Derivados de azaindol
EP2970119B1 (en) * 2013-03-14 2021-11-03 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
GB201310460D0 (en) * 2013-06-12 2013-07-24 Lytix Biopharma As Compounds
CN105473550B (zh) * 2013-07-01 2019-02-15 百时美施贵宝公司 Ido抑制剂
US9371321B2 (en) 2014-01-09 2016-06-21 Astrazeneca Ab Azaindole derivatives
WO2020142559A1 (en) 2018-12-31 2020-07-09 Biomea Fusion, Llc Inhibitors of menin-mll interaction
US11084825B2 (en) 2018-12-31 2021-08-10 Biomea Fusion, Llc Substituted pyridines as irreversible inhibitors of menin-MLL interaction

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376529B1 (en) * 1995-06-07 2002-04-23 Peng Cho Tang Mono- and bis-indolylquinones and prophylactic and therapeutic uses thereof
EP0831809A4 (en) * 1995-06-07 2001-11-28 Sugen Inc METHODS AND COMPOUNDS FOR INHIBITING ADAPTIVE PROTEIN / TYROSINE KINASE INTERACTIONS
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
IL159506A0 (en) * 2001-06-23 2004-06-01 Aventis Pharma Inc Pyrrolopyrimidines as protein kinase inhibitors
GB0115393D0 (en) 2001-06-23 2001-08-15 Aventis Pharma Ltd Chemical compounds
CA2464214C (en) * 2001-10-22 2011-02-08 The Research Foundation Of State University Of New York Protein kinase and phosphatase inhibitors, methods for designing them, and methods of using them
PT1539742E (pt) * 2002-06-24 2007-01-31 Schering Corp Derivados de índole úteis como antagonistas h3 de histamina
FR2842526B1 (fr) * 2002-07-16 2007-07-13 Aventis Pharma Sa Compositions pharmaceutiques contenant un derive de 3-guanidinocarbonyl-1-heteroaryl-indole, procede de preparation a titre de medicaments
JP2004149429A (ja) * 2002-10-29 2004-05-27 Takeda Chem Ind Ltd インドール化合物およびその用途
US7429596B2 (en) 2003-06-20 2008-09-30 The Regents Of The University Of California 1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof
GB0500492D0 (en) 2005-01-11 2005-02-16 Cyclacel Ltd Compound
EP2397476A3 (en) 2005-07-22 2011-12-28 Shionogi & Co., Ltd. Indole derivative having PGD2 receptor antagonist activity

Also Published As

Publication number Publication date
FR2878849A1 (fr) 2006-06-09
US7566736B2 (en) 2009-07-28
EP1841762A1 (fr) 2007-10-10
TNSN07167A1 (fr) 2008-11-21
WO2006061493A1 (fr) 2006-06-15
UY29248A1 (es) 2006-06-30
US20070259910A1 (en) 2007-11-08
CN101098868A (zh) 2008-01-02
SV2006002319A (es) 2006-07-07
AU2005313253A1 (en) 2006-06-15
AR052257A1 (es) 2007-03-07
FR2878849B1 (fr) 2008-09-12
CA2586991A1 (fr) 2006-06-15
PA8654701A1 (es) 2006-07-03
TW200634007A (en) 2006-10-01

Similar Documents

Publication Publication Date Title
GT200500357A (es) Indazoles substituidos, composicones que los comprenden, procedimiento de su preparacion y utilizacion
NI200800020A (es) 7-aza-indazoles sustituidos, composiciones que los contienen, procedimiento de fabricación y utilización.
CR9786A (es) Compuestos de bencimidazol-tiofeno
CR11548A (es) Azolilmetiloxiranos, su uso y agentes que los contienen
PA8667201A1 (es) Nuevos compuestos farmaceuticos
CR8767A (es) Indazoles sustituidos, composiciones que los contienen, procedimiento de preparacion y su uso
GT200600200A (es) Composicion farmaceutica que contienen gestagenos y/o estrogenos y 5-metil-(6s)-tetrahidrofolato
CR9081A (es) Inhibidores de la interaccion entre mdm2 y p53
NO20083011L (no) Modulatorer av muskarine receptorer
HN2008000179A (es) Compuestos triciclicos,composiciones y procedimientos
UY31563A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
UY29361A1 (es) Pirroles e imidazoles sustituídos, composiciones que los contienen, procedimiento de fabricación y utilización
HN2008001393A (es) Derivados de 1,2,4,5- tetrahidro -3h- benzazepinas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen
UY31562A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
UY31560A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
HN2009000566A (es) Nuevos derivados de diosmetina, su procedimiento de prearacion y las composiciones farmaceuticas que lo contienen.
ECSP088252A (es) 7-aza-indazoles sustituidos, composiciones que los contienen, procedimiento de fabricación y utilización
AR047759A1 (es) Derivados de fenil - piperazina como moduladores de receptores muscarnicos
UY30308A1 (es) Moduladores de mglur5 v
UY31273A1 (es) Fenilendiaminas sustituidas como inhibidores de la interaccion entre mdm2 y p53
CR9391A (es) Derivados de indanil-piperazinas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
SV2006002384A (es) Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricacion y utilizacion
CR11584A (es) Derivados de oxindol sustituidos y uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina
HN2011000404A (es) Derivados de enfumafungina y composicion comprendiendo los mismos
DOP2006000028A (es) Pirroles sustituidos, composiciones que los contienen, proceso de fabricación y utilización