GR960300021T1 - 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative - Google Patents

2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative

Info

Publication number: GR960300021T1
Authority: GR; Greece
Prior art keywords: purin; dihydro; oxo; methoxy; amino
Prior art date: 1994-07-28

Application number

GR960300021T

Other languages

English (en)

Inventor

John J Nestor

Scott W Womble

Hans Maag

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-28

Filing date

1996-04-30

Publication date

1996-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23079211&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR960300021(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-04-30 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1996-04-30 Publication of GR960300021T1 publication Critical patent/GR960300021T1/el

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

GR960300021T 1994-07-28 1996-04-30 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative GR960300021T1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28189394A	1994-07-28	1994-07-28

Publications (1)

Publication Number	Publication Date
GR960300021T1 true GR960300021T1 (en)	1996-04-30

Family

ID=23079211

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
GR960300021T GR960300021T1 (en)	1994-07-28	1996-04-30	2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
GR990401760T GR3030678T3 (en)	1994-07-28	1999-07-02	2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
GR990401760T GR3030678T3 (en)	1994-07-28	1999-07-02	2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative

Country Status (33)

Country	Link
EP (1)	EP0694547B1 (el)
JP (1)	JP3090305B2 (el)
KR (1)	KR100358626B1 (el)
CN (1)	CN1045089C (el)
AT (1)	ATE179173T1 (el)
AU (1)	AU697107B2 (el)
BR (1)	BR9503468A (el)
CA (1)	CA2154721C (el)
CO (1)	CO4410181A1 (el)
CY (2)	CY2180B1 (el)
CZ (1)	CZ290511B6 (el)
DE (3)	DE694547T1 (el)
DK (1)	DK0694547T3 (el)
ES (1)	ES2083348T3 (el)
FI (1)	FI112080B (el)
GR (2)	GR960300021T1 (el)
HK (1)	HK1012339A1 (el)
HU (1)	HU216867B (el)
IL (1)	IL114735A (el)
LU (1)	LU91136I2 (el)
MA (1)	MA23631A1 (el)
MY (1)	MY114393A (el)
NL (1)	NL300071I2 (el)
NO (2)	NO312899B1 (el)
NZ (1)	NZ272652A (el)
PE (1)	PE32296A1 (el)
PL (1)	PL180609B1 (el)
RU (1)	RU2133749C1 (el)
SA (1)	SA95160158B1 (el)
TR (1)	TR199500895A2 (el)
TW (1)	TW434242B (el)
UY (1)	UY24006A1 (el)
ZA (1)	ZA956228B (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6458772B1 (en)	1909-10-07	2002-10-01	Medivir Ab	Prodrugs
AU1592897A (en) *	1996-01-26	1997-08-20	F. Hoffmann-La Roche Ag	Process for preparing purine derivatives
US5840890A (en) *	1996-01-26	1998-11-24	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5756736A (en) *	1996-01-26	1998-05-26	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5700936A (en) *	1996-01-26	1997-12-23	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
KR100491941B1 (ko) *	1996-01-26	2005-08-05	에프. 호프만-라 로슈 아게	푸린유도체의제조방법
US5869493A (en) *	1996-02-16	1999-02-09	Medivir Ab	Acyclic nucleoside derivatives
US6703394B2 (en)	1996-02-16	2004-03-09	Medivir Ab	Acyclic nucleoside derivatives
ATE227289T1 (de) *	1997-02-10	2002-11-15	Medivir Ab	Verfahren zur herstellung von azyklischen nukleosiden
US6184376B1 (en)	1997-02-10	2001-02-06	Mediver Ab	Synthesis of acyclic nucleoside derivatives
DE69829784T2 (de) *	1997-08-15	2006-02-16	Medivir Ab	3'-Fluorierte Guanosinderivate zur Behandlung oder Prophylaxe von HBV- oder retroviralen Infektionen
AU1711599A (en) *	1997-12-19	1999-07-12	Bristol-Myers Squibb Company	Prodrugs of lobucavir and methods of use
WO1999051613A1 (en) *	1998-04-03	1999-10-14	Medivir Ab	Prodrugs of phosphorous-containing pharmaceuticals
KR20030015655A (ko) *	2001-08-17	2003-02-25	한미약품공업 주식회사	항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물
JP4497930B2 (ja) *	2002-04-23	2010-07-07	アベンティス・ファーマスーティカルズ・インコーポレイテツド	インターロイキン−４遺伝子発現抑制剤としての３−置換アミノ−１Ｈ−インドール−２−カルボン酸および３−置換アミノ−ベンゾ（ｂ）チオフェン−２−カルボン酸誘導体
ES2534713T3 (es)	2002-10-16	2015-04-27	Takeda Pharmaceutical Company Limited	Preparaciones sólidas estables
AU2004206821C1 (en)	2003-01-14	2009-10-01	Gilead Sciences, Inc.	Compositions and methods for combination antiviral therapy
WO2005021549A1 (en) *	2003-08-28	2005-03-10	Ranbaxy Laboratories Limited	Amorphous valganciclovir hydrochloride
EP1768668A2 (en)	2004-06-16	2007-04-04	Tap Pharmaceutical Products, Inc.	Multiple ppi dosage form
EP2626368B1 (en) *	2004-07-19	2016-12-21	Biocon Limited	Insulin-oligomer conjugates, formulations and uses thereof
TWI471145B (zh)	2005-06-13	2015-02-01	Bristol Myers Squibb & Gilead Sciences Llc	單一式藥學劑量型
TWI375560B (en)	2005-06-13	2012-11-01	Gilead Sciences Inc	Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
ZA200702234B (en) *	2006-03-21	2008-07-30	Cipla Ltd	Preparation of ester of purine derivatives
CN102014638A (zh)	2007-10-12	2011-04-13	武田制药北美公司	与食物摄入无关的治疗胃肠病症的方法
EP2714691B1 (en) *	2011-05-31	2016-09-07	Pharmathen S.A.	Process for the preparation of 2-amino-9-((2-phenyl-1,3-dioxan-5-yloxy)methyl)-1h-purin-6(9h)-one compound useful in the preparation of valganciclovir
KR102312533B1 (ko)	2021-02-24	2021-10-15	주식회사 이웅	자동 스패너

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8202626A (nl) *	1982-06-29	1984-01-16	Stichting Rega V Z W	Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
IE842642L (en) *	1983-10-31	1985-04-30	Harvard College	Purine Derivatives
FI91959C (fi) *	1984-12-12	1994-09-12	Syntex Inc	Menetelmä valmistaa alkoksimetyylieetteri- ja alkoksimetyyliesterijohdoksia
AP160A (en) *	1987-08-15	1991-11-18	The Wellcome Foundation Ltd	Therapeutic acyclic nucleosides.
EP0375329B1 (en) *	1988-12-19	1995-05-31	The Wellcome Foundation Limited	Antiviral pyrimidine and purine compounds, process for their preparation and pharmaceutical compositions containing them

1995
- 1995-07-10 PE PE1995273436A patent/PE32296A1/es not_active IP Right Cessation
- 1995-07-19 EP EP95111319A patent/EP0694547B1/en not_active Expired - Lifetime
- 1995-07-19 ES ES95111319T patent/ES2083348T3/es not_active Expired - Lifetime
- 1995-07-19 DE DE0694547T patent/DE694547T1/de active Pending
- 1995-07-19 AT AT95111319T patent/ATE179173T1/de active
- 1995-07-19 DE DE2002199032 patent/DE10299032I2/de active Active
- 1995-07-19 DE DE69509173T patent/DE69509173T2/de not_active Expired - Lifetime
- 1995-07-19 DK DK95111319T patent/DK0694547T3/da active
- 1995-07-21 TR TR95/00895A patent/TR199500895A2/xx unknown
- 1995-07-26 HU HU9502238A patent/HU216867B/hu unknown
- 1995-07-26 CA CA002154721A patent/CA2154721C/en not_active Expired - Lifetime
- 1995-07-26 AU AU27195/95A patent/AU697107B2/en not_active Expired
- 1995-07-26 IL IL114735A patent/IL114735A/en not_active IP Right Cessation
- 1995-07-26 ZA ZA956228A patent/ZA956228B/xx unknown
- 1995-07-26 MA MA23971A patent/MA23631A1/fr unknown
- 1995-07-26 NZ NZ272652A patent/NZ272652A/en not_active IP Right Cessation
- 1995-07-27 PL PL95309812A patent/PL180609B1/pl unknown
- 1995-07-27 BR BR9503468A patent/BR9503468A/pt active Search and Examination
- 1995-07-27 MY MYPI95002156A patent/MY114393A/en unknown
- 1995-07-27 JP JP07190953A patent/JP3090305B2/ja not_active Expired - Lifetime
- 1995-07-27 UY UY24006A patent/UY24006A1/es not_active IP Right Cessation
- 1995-07-27 CO CO95033418A patent/CO4410181A1/es unknown
- 1995-07-27 FI FI953592A patent/FI112080B/fi active Protection Beyond IP Right Term
- 1995-07-27 RU RU95113148A patent/RU2133749C1/ru active
- 1995-07-27 CZ CZ19951939A patent/CZ290511B6/cs not_active IP Right Cessation
- 1995-07-27 KR KR1019950022600A patent/KR100358626B1/ko not_active IP Right Cessation
- 1995-07-27 NO NO19952977A patent/NO312899B1/no not_active IP Right Cessation
- 1995-07-27 CN CN95109671A patent/CN1045089C/zh not_active Expired - Lifetime
- 1995-07-27 TW TW084107779A patent/TW434242B/zh not_active IP Right Cessation
- 1995-08-14 SA SA95160158A patent/SA95160158B1/ar unknown
1996
- 1996-04-30 GR GR960300021T patent/GR960300021T1/el unknown
1998
- 1998-12-15 HK HK98113443A patent/HK1012339A1/xx not_active IP Right Cessation
1999
- 1999-07-02 GR GR990401760T patent/GR3030678T3/el unknown
2000
- 2000-08-10 CY CY0000039A patent/CY2180B1/xx unknown
2001
- 2001-11-23 NL NL300071C patent/NL300071I2/nl unknown
2003
- 2003-01-10 NO NO2003001C patent/NO2003001I2/no unknown
- 2003-05-21 LU LU91136C patent/LU91136I2/fr unknown
2004
- 2004-10-20 CY CY200400003C patent/CY2004003I2/el unknown

Also Published As

Publication number	Publication date
ES2083348T3 (es)	1999-08-01
TW434242B (en)	2001-05-16
FI112080B (fi)	2003-10-31
IL114735A (en)	1998-06-15
DK0694547T3 (da)	2000-01-03
PL180609B1 (pl)	2001-03-30
CN1045089C (zh)	1999-09-15
HU9502238D0 (en)	1995-09-28
ATE179173T1 (de)	1999-05-15
CZ290511B6 (cs)	2002-08-14
CA2154721C (en)	2001-01-02
NO952977D0 (no)	1995-07-27
UY24006A1 (es)	2001-07-31
DE694547T1 (de)	1996-10-24
DE69509173D1 (de)	1999-05-27
JPH0841061A (ja)	1996-02-13
TR199500895A2 (tr)	1996-06-21
RU95113148A (ru)	1997-06-27
KR960004345A (ko)	1996-02-23
DE10299032I2 (de)	2006-06-14
CZ193995A3 (en)	1996-02-14
AU2719595A (en)	1996-02-08
EP0694547A3 (en)	1996-06-05
HU216867B (hu)	1999-09-28
NL300071I1 (nl)	2002-02-01
NL300071I2 (nl)	2002-03-01
NZ272652A (en)	1996-12-20
GR3030678T3 (en)	1999-11-30
RU2133749C1 (ru)	1999-07-27
SA95160158B1 (ar)	2006-05-20
CN1122804A (zh)	1996-05-22
JP3090305B2 (ja)	2000-09-18
ZA956228B (en)	1996-02-22
CY2180B1 (en)	2002-08-23
FI953592A0 (fi)	1995-07-27
MA23631A1 (fr)	1996-04-01
DE69509173T2 (de)	1999-10-21
LU91136I2 (fr)	2005-07-06
NO312899B1 (no)	2002-07-15
FI953592A (fi)	1996-01-29
CA2154721A1 (en)	1996-01-29
NO952977L (no)	1996-01-29
IL114735A0 (en)	1995-11-27
DE10299032I1 (de)	2003-01-23
PL309812A1 (en)	1996-02-05
ES2083348T1 (es)	1996-04-16
BR9503468A (pt)	1996-02-27
CY2004003I1 (el)	2009-11-04
MY114393A (en)	2002-10-31
HK1012339A1 (en)	1999-07-30
CY2004003I2 (el)	2009-11-04
AU697107B2 (en)	1998-09-24
CO4410181A1 (es)	1997-01-09
PE32296A1 (es)	1996-08-07
EP0694547A2 (en)	1996-01-31
HUT73246A (en)	1996-07-29
NO2003001I2 (no)	2007-06-11
KR100358626B1 (ko)	2003-01-14
EP0694547B1 (en)	1999-04-21

Publication	Publication Date	Title
CY2180B1 (en)	2002-08-23	2-(2Amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
FI20020059A (fi)	2002-01-11	Enantiomeeripuhtaat diatsabisyklo/4.3.0/nonaanijohdannaiset
EP0563345A4 (en)	1994-09-28	Novel 4-arylpiperazines and 4-arylpiperidines
AU8979191A (en)	1992-06-25	3,7-disubstituted indole derivatives
ES2119912T3 (es)	1998-10-16	Nuevos aminometilenpeptidos como inmunosupresores.
CA2244680A1 (en)	1997-07-31	Process for preparing purine derivatives
ATE172985T1 (de)	1998-11-15	Sulfonamidaminomethylenderivate als immunsuppressiva
DE69312776T2 (de)	1998-01-15	Fungizide 3,4-Diaryl-(5H)-Furan-2-Onederivate
ATE197953T1 (de)	2000-12-15	Pyrrolo(4,3,2-de)chinolin-derivat
SG32424A1 (en)	1995-08-13	2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1, 3-propanediol derivative
AU8803091A (en)	1992-05-28	Method for protecting the myocardium against ischemia