GR862713B - Human manganese superoxide dismutase cdna its expression in bacteria and method of recovering enzymatically active human manganese superoxide dismutase - Google Patents

Human manganese superoxide dismutase cdna its expression in bacteria and method of recovering enzymatically active human manganese superoxide dismutase

Info

Publication number
GR862713B
GR862713B GR862713A GR860102713A GR862713B GR 862713 B GR862713 B GR 862713B GR 862713 A GR862713 A GR 862713A GR 860102713 A GR860102713 A GR 860102713A GR 862713 B GR862713 B GR 862713B
Authority
GR
Greece
Prior art keywords
superoxide dismutase
manganese superoxide
human manganese
bacteria
expression
Prior art date
Application number
GR862713A
Other languages
Greek (el)
Inventor
Hartman R Jacob
Beck Yaffa
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Publication of GR862713B publication Critical patent/GR862713B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR862713A 1985-11-22 1986-11-13 Human manganese superoxide dismutase cdna its expression in bacteria and method of recovering enzymatically active human manganese superoxide dismutase GR862713B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80109085A 1985-11-22 1985-11-22
US90705186A 1986-09-12 1986-09-12

Publications (1)

Publication Number Publication Date
GR862713B true GR862713B (en) 1987-03-24

Family

ID=27122291

Family Applications (1)

Application Number Title Priority Date Filing Date
GR862713A GR862713B (en) 1985-11-22 1986-11-13 Human manganese superoxide dismutase cdna its expression in bacteria and method of recovering enzymatically active human manganese superoxide dismutase

Country Status (21)

Country Link
JP (2) JP2609449B2 (en)
AT (1) AT400443B (en)
AU (1) AU607897B2 (en)
BE (1) BE905796A (en)
CA (1) CA1341362C (en)
CH (1) CH676990A5 (en)
DE (1) DE3639725C2 (en)
DK (1) DK534686A (en)
ES (1) ES2003518A6 (en)
FI (1) FI90353C (en)
FR (1) FR2590591B1 (en)
GB (1) GB2183658B (en)
GR (1) GR862713B (en)
HK (1) HK75195A (en)
IE (1) IE59498B1 (en)
IL (2) IL80702A0 (en)
IT (1) IT1205418B (en)
LU (1) LU86676A1 (en)
NL (1) NL8602960A (en)
PT (1) PT83792B (en)
SE (1) SE8604884L (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610520B1 (en) 1985-11-22 2003-08-26 Bio-Technology General Corp. Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
JPS62215532A (en) * 1986-03-18 1987-09-22 Ube Ind Ltd Anti-inflammatory drug
JPH0643341B2 (en) * 1986-03-27 1994-06-08 宇部興産株式会社 Organ function improving agent
JPH0643340B2 (en) * 1986-09-03 1994-06-08 宇部興産株式会社 Ischemic heart disease drug
CA1339299C (en) * 1986-09-12 1997-08-19 Jacob R. Hartman Human manganese superoxide dismutase dna; its expression; method of recovering human manganese superoxide dismutase, human manganese superoxide dismutase analogs or human manganese superoxide dismutase mutants; uses;compositions; and methods of treatment
JPS6377822A (en) * 1986-09-18 1988-04-08 Ube Ind Ltd Organ function improver
US6326003B1 (en) 1986-10-14 2001-12-04 Chiron Corporation Manganese superoxide dismutase cloning and expression in microorganisms
US5260204A (en) * 1987-03-14 1993-11-09 Boehringer Ingelheim International Gmbh Human manganese superoxide dismutase (hMn-SOD)
ES2083357T3 (en) * 1987-03-14 1996-04-16 Boehringer Ingelheim Int HUMAN MANGANESE-SUPEROXIDE-DISMUTASE (HMN-SOD).
JPH01233228A (en) * 1988-03-11 1989-09-19 Toyo Jozo Co Ltd Metastasis preventive of malignant tumor cells
US5772996A (en) * 1990-08-03 1998-06-30 Public Health Laboratory Service Board Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
DE4038563A1 (en) * 1990-12-04 1992-06-11 Gruenenthal Gmbh USE OF SUPEROXIDE DISMUTASES FOR PROPHYLAXIS AND / OR TREATMENT OF ORGAN FAILURE IN RISK PATIENTS WITH POLYTRAUMA
DE59310242D1 (en) * 1992-09-09 2002-01-17 Bio Technology General Corp Use of manganese superoxide dismutase (Mn-SOD) for the manufacture of medicaments for the treatment of diseases in low doses
DE4239877C1 (en) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilized superoxide dismutase (SOD) composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56102787A (en) * 1980-01-18 1981-08-17 Mamoru Sugiura Preparation of human placenta superoxide dismutase
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
DE3486493T2 (en) * 1983-10-03 2003-05-22 Chiron Corp Cloning of superoxide dismutase and expression in microorganisms

Also Published As

Publication number Publication date
IT1205418B (en) 1989-03-15
GB8627294D0 (en) 1986-12-17
SE8604884L (en) 1987-05-23
BE905796A (en) 1987-03-16
AU6497586A (en) 1987-05-28
GB2183658A (en) 1987-06-10
FI90353C (en) 1994-01-25
DE3639725A1 (en) 1987-07-23
IL106449A0 (en) 1993-11-15
FR2590591B1 (en) 1989-12-01
CH676990A5 (en) 1991-03-28
JP2609449B2 (en) 1997-05-14
ATA308986A (en) 1995-05-15
AT400443B (en) 1995-12-27
CA1341362C (en) 2002-05-28
IT8667865A0 (en) 1986-11-21
AU607897B2 (en) 1991-03-21
JPS62289187A (en) 1987-12-16
FR2590591A1 (en) 1987-05-29
JPH08289792A (en) 1996-11-05
JP2967557B2 (en) 1999-10-25
DE3639725C2 (en) 1998-02-19
IL106449A (en) 1997-02-18
IL80702A0 (en) 1987-02-27
FI90353B (en) 1993-10-15
FI864756A (en) 1987-05-23
IE862851L (en) 1987-05-22
IE59498B1 (en) 1994-03-09
PT83792B (en) 1989-01-17
DK534686D0 (en) 1986-11-07
SE8604884D0 (en) 1986-11-14
DK534686A (en) 1987-05-23
LU86676A1 (en) 1987-05-04
PT83792A (en) 1986-12-01
GB2183658B (en) 1990-04-25
ES2003518A6 (en) 1988-11-01
NL8602960A (en) 1987-06-16
HK75195A (en) 1995-05-26
FI864756A0 (en) 1986-11-21

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