GR3035853T3 - Novel optionally substituted phenylimidazolidines, intermediates and process for their preparation, their use as drugs and pharmaceutical compositions containing them - Google Patents

Novel optionally substituted phenylimidazolidines, intermediates and process for their preparation, their use as drugs and pharmaceutical compositions containing them

Info

Publication number
GR3035853T3
GR3035853T3 GR20010400704T GR20010400704T GR3035853T3 GR 3035853 T3 GR3035853 T3 GR 3035853T3 GR 20010400704 T GR20010400704 T GR 20010400704T GR 20010400704 T GR20010400704 T GR 20010400704T GR 3035853 T3 GR3035853 T3 GR 3035853T3
Authority
GR
Greece
Prior art keywords
optionally substituted
pct
intermediates
drugs
preparation
Prior art date
Application number
GR20010400704T
Other languages
English (en)
Inventor
Andre Claussner
Francois Goubet
Jean-Georges Teutsch
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9400042A external-priority patent/FR2715402B1/fr
Priority claimed from FR9410660A external-priority patent/FR2724169B1/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of GR3035853T3 publication Critical patent/GR3035853T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
GR20010400704T 1994-01-05 2001-05-11 Novel optionally substituted phenylimidazolidines, intermediates and process for their preparation, their use as drugs and pharmaceutical compositions containing them GR3035853T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9400042A FR2715402B1 (fr) 1994-01-05 1994-01-05 Nouvelles phénylimidazolines éventuellement substituées, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
FR9410660A FR2724169B1 (fr) 1994-09-06 1994-09-06 Nouvelles phenylimidazolidines eventuellement substituees, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
PCT/FR1995/000004 WO1995018794A1 (fr) 1994-01-05 1995-01-04 Nouvelles phenylimidazolidines eventuellement substituees, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
GR3035853T3 true GR3035853T3 (en) 2001-08-31

Family

ID=26230882

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400704T GR3035853T3 (en) 1994-01-05 2001-05-11 Novel optionally substituted phenylimidazolidines, intermediates and process for their preparation, their use as drugs and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US5750553A (el)
EP (1) EP0738263B1 (el)
JP (1) JPH09507241A (el)
KR (1) KR100372065B1 (el)
CN (1) CN1113873C (el)
AT (1) ATE200281T1 (el)
AU (1) AU687152B2 (el)
BR (1) BR9506457A (el)
CA (1) CA2180379A1 (el)
DE (1) DE69520560T2 (el)
DK (1) DK0738263T3 (el)
ES (1) ES2156204T3 (el)
FI (1) FI112475B (el)
GR (1) GR3035853T3 (el)
HU (1) HUT76299A (el)
IL (1) IL111908A (el)
MA (1) MA23423A1 (el)
PT (1) PT738263E (el)
TW (1) TW521073B (el)
WO (1) WO1995018794A1 (el)

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US6828458B2 (en) 2000-05-25 2004-12-07 Biophysica, Inc. Topical antiandrogen for hair loss and other hyperandrogenic conditions
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Also Published As

Publication number Publication date
FI962754A (fi) 1996-07-04
FI962754A0 (fi) 1996-07-04
DK0738263T3 (da) 2001-06-18
IL111908A0 (en) 1995-03-15
KR100372065B1 (ko) 2003-05-12
CA2180379A1 (fr) 1995-07-13
US5750553A (en) 1998-05-12
BR9506457A (pt) 1997-10-07
IL111908A (en) 2003-05-29
TW521073B (en) 2003-02-21
ES2156204T3 (es) 2001-06-16
DE69520560D1 (de) 2001-05-10
HUT76299A (en) 1997-07-28
HU9601836D0 (en) 1996-09-30
JPH09507241A (ja) 1997-07-22
MA23423A1 (fr) 1995-10-01
AU687152B2 (en) 1998-02-19
EP0738263A1 (fr) 1996-10-23
PT738263E (pt) 2001-08-30
DE69520560T2 (de) 2001-09-13
AU1457395A (en) 1995-08-01
EP0738263B1 (fr) 2001-04-04
WO1995018794A1 (fr) 1995-07-13
CN1141631A (zh) 1997-01-29
ATE200281T1 (de) 2001-04-15
FI112475B (fi) 2003-12-15
CN1113873C (zh) 2003-07-09

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