GR3017282T3 - Novel arylpyridazines, their manufacture, use and medicaments containing them. - Google Patents
Novel arylpyridazines, their manufacture, use and medicaments containing them.Info
- Publication number
- GR3017282T3 GR3017282T3 GR950402400T GR950402400T GR3017282T3 GR 3017282 T3 GR3017282 T3 GR 3017282T3 GR 950402400 T GR950402400 T GR 950402400T GR 950402400 T GR950402400 T GR 950402400T GR 3017282 T3 GR3017282 T3 GR 3017282T3
- Authority
- GR
- Greece
- Prior art keywords
- pct
- arylpyridazines
- novel
- manufacture
- medicaments containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH142489 | 1989-04-17 | ||
| PCT/EP1990/000578 WO1990012789A1 (de) | 1989-04-17 | 1990-04-11 | Neue arylpyridazine, ihre herstellung, verwendung und sie enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3017282T3 true GR3017282T3 (en) | 1995-11-30 |
Family
ID=4210136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR950402400T GR3017282T3 (en) | 1989-04-17 | 1995-08-31 | Novel arylpyridazines, their manufacture, use and medicaments containing them. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5236918A (el) |
| EP (2) | EP0393500A1 (el) |
| JP (1) | JPH04504576A (el) |
| AT (1) | ATE124401T1 (el) |
| AU (1) | AU640137B2 (el) |
| CA (1) | CA2065364A1 (el) |
| DE (1) | DE59009351D1 (el) |
| DK (1) | DK0469013T3 (el) |
| ES (1) | ES2075202T3 (el) |
| GR (1) | GR3017282T3 (el) |
| WO (1) | WO1990012789A1 (el) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06501941A (ja) * | 1990-10-16 | 1994-03-03 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | アリールピリダジノン |
| US5449676A (en) * | 1991-04-26 | 1995-09-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pyridazines |
| AU2229992A (en) | 1991-07-05 | 1993-02-11 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Use of substituted pyridazines against dermatosis |
| DE4207822C2 (de) * | 1992-03-12 | 1994-03-03 | Byk Gulden Lomberg Chem Fab | Neue Verwendung substituierter Pyridazine |
| GB9212673D0 (en) * | 1992-06-15 | 1992-07-29 | Celltech Ltd | Chemical compounds |
| GB9222253D0 (en) * | 1992-10-23 | 1992-12-09 | Celltech Ltd | Chemical compounds |
| GB9226830D0 (en) * | 1992-12-23 | 1993-02-17 | Celltech Ltd | Chemical compounds |
| US5622977A (en) * | 1992-12-23 | 1997-04-22 | Celltech Therapeutics Limited | Tri-substituted (aryl or heteroaryl) derivatives and pharmaceutical compositions containing the same |
| GB9304920D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| GB9304919D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| ATE260911T1 (de) * | 1993-12-22 | 2004-03-15 | Celltech R&D Ltd | Trisubstituierte phenyl-derivate, verfahren zu deren herstellung und deren verwendung als phosphodiesterase (typ iv) hemmstoffe |
| GB9326173D0 (en) * | 1993-12-22 | 1994-02-23 | Celltech Ltd | Chemical compounds and process |
| US5786354A (en) * | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation |
| US6245774B1 (en) | 1994-06-21 | 2001-06-12 | Celltech Therapeutics Limited | Tri-substituted phenyl or pyridine derivatives |
| GB9412573D0 (en) * | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds |
| GB9412571D0 (en) | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds |
| GB9412672D0 (en) * | 1994-06-23 | 1994-08-10 | Celltech Ltd | Chemical compounds |
| GB9523675D0 (en) | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9526246D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9526243D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9526245D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9608435D0 (en) * | 1996-04-24 | 1996-06-26 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9619284D0 (en) * | 1996-09-16 | 1996-10-30 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9622363D0 (en) | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9625184D0 (en) * | 1996-12-04 | 1997-01-22 | Celltech Therapeutics Ltd | Chemical compounds |
| JP2001507349A (ja) | 1996-12-23 | 2001-06-05 | セルテック セラピューティックス リミテッド | 縮合多環式２−アミノピリミジン誘導体、それらの製造およびたんぱく質チロシンキナーゼ抑制因子としてのそれらの使用 |
| GB9705361D0 (en) * | 1997-03-14 | 1997-04-30 | Celltech Therapeutics Ltd | Chemical compounds |
| GB9713087D0 (en) * | 1997-06-20 | 1997-08-27 | Celltech Therapeutics Ltd | Chemical compounds |
| ATE258930T1 (de) * | 1997-12-15 | 2004-02-15 | Altana Pharma Ag | Dihydrobenzifurane |
| GB9914258D0 (en) | 1999-06-18 | 1999-08-18 | Celltech Therapeutics Ltd | Chemical compounds |
| KR100701904B1 (ko) | 1999-08-21 | 2007-04-02 | 알타나 파마 아게 | Ｐｄｅ 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합 |
| GB9924862D0 (en) * | 1999-10-20 | 1999-12-22 | Celltech Therapeutics Ltd | Chemical compounds |
| IL159120A0 (en) * | 2001-05-29 | 2004-05-12 | Schering Ag | Cdk inhibiting pyrimidines, production thereof and their use as medicaments |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| KR20050115331A (ko) | 2003-04-01 | 2005-12-07 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | 불임증 포스포디에스터라제의 억제제 |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| EP3718557A3 (en) | 2013-02-25 | 2020-10-21 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法 |
| NZ717739A (en) | 2013-08-09 | 2023-12-22 | Ardelyx Inc | Compounds and methods for inhibiting phosphate transport |
| US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2854600A1 (de) * | 1978-12-18 | 1980-06-26 | Basf Ag | Substituierte cyanamide |
| GR82072B (el) * | 1983-05-11 | 1984-12-13 | Byk Gulden Lomberg Chem Fab | |
| DK159431C (da) * | 1984-05-10 | 1991-03-18 | Byk Gulden Lomberg Chem Fab | 6-phenyl-3(2h)-pyridazinoner, fremgangsmaade til fremstilling deraf, laegemidler indeholdende disse samt anvendelse af forbindelserne til fremstilling af laegemidler |
| DE3525977A1 (de) * | 1985-07-20 | 1987-01-29 | Bayer Ag | Verfahren zur herstellung von 2-cyanamino-pyrimidin-derivaten |
-
1990
- 1990-04-11 WO PCT/EP1990/000578 patent/WO1990012789A1/de active IP Right Grant
- 1990-04-11 US US07/768,754 patent/US5236918A/en not_active Expired - Fee Related
- 1990-04-11 JP JP2505945A patent/JPH04504576A/ja active Pending
- 1990-04-11 EP EP90106990A patent/EP0393500A1/de active Pending
- 1990-04-11 CA CA002065364A patent/CA2065364A1/en not_active Abandoned
- 1990-04-11 AT AT90906165T patent/ATE124401T1/de not_active IP Right Cessation
- 1990-04-11 EP EP90906165A patent/EP0469013B1/de not_active Expired - Lifetime
- 1990-04-11 AU AU54313/90A patent/AU640137B2/en not_active Ceased
- 1990-04-11 DK DK90906165.7T patent/DK0469013T3/da active
- 1990-04-11 ES ES90906165T patent/ES2075202T3/es not_active Expired - Lifetime
- 1990-04-11 DE DE59009351T patent/DE59009351D1/de not_active Expired - Fee Related
-
1995
- 1995-08-31 GR GR950402400T patent/GR3017282T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5431390A (en) | 1990-11-16 |
| US5236918A (en) | 1993-08-17 |
| ATE124401T1 (de) | 1995-07-15 |
| DK0469013T3 (da) | 1995-10-02 |
| WO1990012789A1 (de) | 1990-11-01 |
| AU640137B2 (en) | 1993-08-19 |
| ES2075202T3 (es) | 1995-10-01 |
| EP0469013A1 (de) | 1992-02-05 |
| CA2065364A1 (en) | 1990-10-18 |
| EP0393500A1 (de) | 1990-10-24 |
| DE59009351D1 (de) | 1995-08-03 |
| EP0469013B1 (de) | 1995-06-28 |
| JPH04504576A (ja) | 1992-08-13 |
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