GB9928703D0 - Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents - Google Patents

Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents

Info

Publication number
GB9928703D0
GB9928703D0 GBGB9928703.9A GB9928703A GB9928703D0 GB 9928703 D0 GB9928703 D0 GB 9928703D0 GB 9928703 A GB9928703 A GB 9928703A GB 9928703 D0 GB9928703 D0 GB 9928703D0
Authority
GB
United Kingdom
Prior art keywords
acryloyl
preparation
antitumour agents
peptidic derivatives
peptidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9928703.9A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia and Upjohn SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn SpA filed Critical Pharmacia and Upjohn SpA
Priority to GBGB9928703.9A priority Critical patent/GB9928703D0/en
Publication of GB9928703D0 publication Critical patent/GB9928703D0/en
Priority to JP2001541867A priority patent/JP2003515586A/en
Priority to CA002395094A priority patent/CA2395094A1/en
Priority to KR1020027007127A priority patent/KR20020084069A/en
Priority to PCT/EP2000/011714 priority patent/WO2001040181A1/en
Priority to BR0016115-2A priority patent/BR0016115A/en
Priority to EP00993255A priority patent/EP1242374A1/en
Priority to NZ519581A priority patent/NZ519581A/en
Priority to AU28370/01A priority patent/AU781657B2/en
Priority to ZA200204722A priority patent/ZA200204722B/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GBGB9928703.9A 1999-12-03 1999-12-03 Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents Ceased GB9928703D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GBGB9928703.9A GB9928703D0 (en) 1999-12-03 1999-12-03 Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents
AU28370/01A AU781657B2 (en) 1999-12-03 2000-11-23 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents
PCT/EP2000/011714 WO2001040181A1 (en) 1999-12-03 2000-11-23 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents
CA002395094A CA2395094A1 (en) 1999-12-03 2000-11-23 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents
KR1020027007127A KR20020084069A (en) 1999-12-03 2000-11-23 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents
JP2001541867A JP2003515586A (en) 1999-12-03 2000-11-23 Acryloyl peptide derivatives, their preparation, and their use as antitumor agents
BR0016115-2A BR0016115A (en) 1999-12-03 2000-11-23 Peptide derivatives of acrylamide, process for its preparation and use as tumor inhibiting agents
EP00993255A EP1242374A1 (en) 1999-12-03 2000-11-23 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents
NZ519581A NZ519581A (en) 1999-12-03 2000-11-23 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents
ZA200204722A ZA200204722B (en) 1999-12-03 2002-06-12 Acryloyl peptidic derivatives, process for their preparation and their use as antitumor agents.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9928703.9A GB9928703D0 (en) 1999-12-03 1999-12-03 Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents

Publications (1)

Publication Number Publication Date
GB9928703D0 true GB9928703D0 (en) 2000-02-02

Family

ID=10865724

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9928703.9A Ceased GB9928703D0 (en) 1999-12-03 1999-12-03 Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents

Country Status (10)

Country Link
EP (1) EP1242374A1 (en)
JP (1) JP2003515586A (en)
KR (1) KR20020084069A (en)
AU (1) AU781657B2 (en)
BR (1) BR0016115A (en)
CA (1) CA2395094A1 (en)
GB (1) GB9928703D0 (en)
NZ (1) NZ519581A (en)
WO (1) WO2001040181A1 (en)
ZA (1) ZA200204722B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011059D0 (en) * 2000-05-08 2000-06-28 Pharmacia & Upjohn Spa Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione
GB0015447D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015446D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites
GB0016447D0 (en) 2000-07-04 2000-08-23 Pharmacia & Upjohn Spa Process for preparing distamycin derivatives
US6576612B1 (en) * 2000-10-02 2003-06-10 Pharmacia Italia S.P.A. Antitumor therapy comprising distamycin derivatives
US6969592B2 (en) 2001-09-26 2005-11-29 Pharmacia Italia S.P.A. Method for predicting the sensitivity to chemotherapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9416005D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
GB9610079D0 (en) * 1996-05-14 1996-07-17 Pharmacia Spa Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9806689D0 (en) * 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents

Also Published As

Publication number Publication date
NZ519581A (en) 2004-05-28
JP2003515586A (en) 2003-05-07
CA2395094A1 (en) 2001-06-07
AU781657B2 (en) 2005-06-02
ZA200204722B (en) 2004-02-03
BR0016115A (en) 2002-08-20
AU2837001A (en) 2001-06-12
WO2001040181A1 (en) 2001-06-07
KR20020084069A (en) 2002-11-04
EP1242374A1 (en) 2002-09-25

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)