GB945507A - New steroid compounds, their production and conversion - Google Patents
New steroid compounds, their production and conversionInfo
- Publication number
- GB945507A GB945507A GB2109162A GB2109162A GB945507A GB 945507 A GB945507 A GB 945507A GB 2109162 A GB2109162 A GB 2109162A GB 2109162 A GB2109162 A GB 2109162A GB 945507 A GB945507 A GB 945507A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methoxymethyl
- acetoxy
- hydroxy
- conversion
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises 3-methoxy -17a -methoxymethyl or -17a - ethoxyethyl-estra- 1,3,5 (10)-trien -17b - ol, 3b - acetoxy-17a -methoxymethyl - androst -5- en - 17b - ol, 3a - acetoxy-20#x-hydroxy -20#x-methoxymethyl -5b - pregnan -11- one and processes for the preparation thereof in which a corresponding 17- or 20-keto steroid, namely 3-methoxy-estra- 1,3,5(10)-trien-17-one, 3b - acetoxy - androst -5- en -17- one or 3a -acetoxy - pregnane -11,20- dione is reacted with an appropriate methoxymethyl or ethoxy methyl magnesium halide to yield the corresponding 17b - hydroxy -17a - methoxymethyl or -17a - ethoxymethyl or 20-hydroxy -20#x-methoxymethyl steroid. Subsequently the products may be treated with a dehydrating agent e.g. oxalic acid or phosphoryl chloride to obtain the corresponding 17- or 20-formyl substituted derivative.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR799660A FR1239359A (en) | 1959-07-08 | 1959-07-08 | Process for the preparation of formyl steroids and products thus obtained |
Publications (1)
Publication Number | Publication Date |
---|---|
GB945507A true GB945507A (en) | 1964-01-02 |
Family
ID=8716953
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2245660A Expired GB945502A (en) | 1959-07-08 | 1960-06-27 | Improvements in or relating to the production of steroid compounds and the compounds thus produced |
GB2109162A Expired GB945507A (en) | 1959-07-08 | 1960-06-27 | New steroid compounds, their production and conversion |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2245660A Expired GB945502A (en) | 1959-07-08 | 1960-06-27 | Improvements in or relating to the production of steroid compounds and the compounds thus produced |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE592735A (en) |
CH (1) | CH387028A (en) |
FR (1) | FR1239359A (en) |
GB (2) | GB945502A (en) |
-
1959
- 1959-07-08 FR FR799660A patent/FR1239359A/en not_active Expired
-
1960
- 1960-06-27 GB GB2245660A patent/GB945502A/en not_active Expired
- 1960-06-27 GB GB2109162A patent/GB945507A/en not_active Expired
- 1960-06-27 CH CH721660A patent/CH387028A/en unknown
- 1960-07-07 BE BE592735A patent/BE592735A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR1239359A (en) | 1960-08-26 |
GB945502A (en) | 1964-01-02 |
BE592735A (en) | 1961-01-09 |
CH387028A (en) | 1965-01-31 |
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