GB912949A - Improvements in and relating to pharmaceutical preparations of quaternary ammonium compounds and the preparation thereof - Google Patents
Improvements in and relating to pharmaceutical preparations of quaternary ammonium compounds and the preparation thereofInfo
- Publication number
- GB912949A GB912949A GB1235458A GB1235458A GB912949A GB 912949 A GB912949 A GB 912949A GB 1235458 A GB1235458 A GB 1235458A GB 1235458 A GB1235458 A GB 1235458A GB 912949 A GB912949 A GB 912949A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxyethyl
- benzyl
- relating
- preparation
- quaternary ammonium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Therapeutic compositions in unit storage form comprise a neutral excipient and a salt having a non-toxic anion and one of the following cations: N - benzyl - N - 2 - hydroxyethyl-N : N - dimethyl ammonium; N - benzyl - N-ethyl - N - 2 - hydroxyethyl - N - methyl ammonium; N-benzyl-N : N - di - (2 - hydroxyethyl) - N - methyl ammonium. Suitable salts are the bromides and p-toluensulphonates. The compositions may be put up into conventional forms e.g. tablets plain, coated and enterically coated, capsules, granules, aqueous and non-aqueous preparations, injectable solutions and suspensions and suppositories. Such forms may also contain conventional flavours, preservatives, anti-oxidants, buffers, suspending, thickening and emulsifying agents, bacteriostats, binders and lubricants.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1235458A GB912949A (en) | 1958-04-18 | 1958-04-18 | Improvements in and relating to pharmaceutical preparations of quaternary ammonium compounds and the preparation thereof |
ES0248742A ES248742A1 (en) | 1958-04-18 | 1959-04-17 | Improvements in and relating to pharmaceutical preparations of quaternary ammonium compounds and the preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1235458A GB912949A (en) | 1958-04-18 | 1958-04-18 | Improvements in and relating to pharmaceutical preparations of quaternary ammonium compounds and the preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GB912949A true GB912949A (en) | 1962-12-12 |
Family
ID=10002981
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1235458A Expired GB912949A (en) | 1958-04-18 | 1958-04-18 | Improvements in and relating to pharmaceutical preparations of quaternary ammonium compounds and the preparation thereof |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES248742A1 (en) |
GB (1) | GB912949A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001433A (en) | 1969-06-23 | 1977-01-04 | Burroughs Wellcome Co. | Quaternary ammonium compounds useful as antifibrillatory agent |
-
1958
- 1958-04-18 GB GB1235458A patent/GB912949A/en not_active Expired
-
1959
- 1959-04-17 ES ES0248742A patent/ES248742A1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001433A (en) | 1969-06-23 | 1977-01-04 | Burroughs Wellcome Co. | Quaternary ammonium compounds useful as antifibrillatory agent |
Also Published As
Publication number | Publication date |
---|---|
ES248742A1 (en) | 1959-09-16 |
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