GB872129A - Process for the production of 3ª-, 12ª--dihydroxy-11-oxo-23-bromospirostane - Google Patents

Process for the production of 3ª-, 12ª--dihydroxy-11-oxo-23-bromospirostane

Info

Publication number
GB872129A
GB872129A GB7978/60A GB797860A GB872129A GB 872129 A GB872129 A GB 872129A GB 7978/60 A GB7978/60 A GB 7978/60A GB 797860 A GB797860 A GB 797860A GB 872129 A GB872129 A GB 872129A
Authority
GB
United Kingdom
Prior art keywords
oxo
bromospirostane
dihydroxy
diacetoxy
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7978/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ERNST BOERINGER ILSE LIEBRECHT
JULIUS LIEBRECHT
WALTER MAYER LIST
Original Assignee
ERNST BOERINGER ILSE LIEBRECHT
JULIUS LIEBRECHT
WALTER MAYER LIST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ERNST BOERINGER ILSE LIEBRECHT, JULIUS LIEBRECHT, WALTER MAYER LIST filed Critical ERNST BOERINGER ILSE LIEBRECHT
Publication of GB872129A publication Critical patent/GB872129A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises 3b ,11 a -diacetoxy-12-oxo-23-bromospirostane and a process for the preparation of 3b ,12b -dihydroxy-11-oxo-23-bromospirostane by reacting 11b ,23-dibromohecogenin acetate with an alkali metal acetate in an organic solvent at a temperature between 50 DEG and 155 DEG C., separating the sparingly soluble impurities from the resulting mixture of 3b ,11(a and b )-diacetoxy-12-oxo-23-bromospirostanes (the 11a isomer predominates), and hydrolysing the compounds of the mixture by heating with aqueous or aqueous-alcoholic alkali. The organic solvent may be alcohol or a solvent in which the alkali metal acetate is soluble such as t-butanol or dimethyl formamide. p Detailed examples are given. Specification 721,953 is referred to.
GB7978/60A 1959-03-05 1960-03-07 Process for the production of 3ª-, 12ª--dihydroxy-11-oxo-23-bromospirostane Expired GB872129A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB52366A DE1092913B (en) 1959-03-05 1959-03-05 Process for the preparation of 3,12-dioxy-11-oxo-23-bromo-spirostane

Publications (1)

Publication Number Publication Date
GB872129A true GB872129A (en) 1961-07-05

Family

ID=6969880

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7978/60A Expired GB872129A (en) 1959-03-05 1960-03-07 Process for the production of 3ª-, 12ª--dihydroxy-11-oxo-23-bromospirostane

Country Status (3)

Country Link
CH (1) CH377809A (en)
DE (1) DE1092913B (en)
GB (1) GB872129A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE965326C (en) * 1954-04-30 1957-06-06 G N R D Patent Holdings Ltd Process for the preparation of 23-bromo-5ª ‡, 22-a-spirostan-3ª ‰, 12ª ‰ -diol-11-one

Also Published As

Publication number Publication date
CH377809A (en) 1964-05-31
DE1092913B (en) 1960-11-17

Similar Documents

Publication Publication Date Title
GB965637A (en) L-ornithine l-aspartate
GB872129A (en) Process for the production of 3ª-, 12ª--dihydroxy-11-oxo-23-bromospirostane
GB1224568A (en) Process for preparing alkyl-3,5-disubstituted-isoxazole 4-carboxylates
GB873221A (en) Production of chloroprene
GB884184A (en) Improvements in or relating to the production of new compounds from wood
GB800171A (en) Process for the production of choline theophyllinate
GB892790A (en) Process for the manufacture of methyl isothiocyanate
GB1011116A (en) Process of producing a 1-halo-1-nitroalkane, and 1-halo-1-nitroalkanes produced by the process
GB844830A (en) Method for preparing succinaldehyde bisulphite compounds
GB892257A (en) Improved process for the production of sorbic acid
GB1115260A (en) A process for the production of carbodiimides and carbodiimide-isocyanate adducts
GB862531A (en) New testosterone derivatives
GB871030A (en) 2-methyl-2-hydroxy-4-(2,2,2-trichloro-1-hydroxyethoxy)-pentane and its production
GB914734A (en) New cyclopentano-naphthalene derivatives and their formation
GB904649A (en) Improved epoxidation of cyclododecatriene process
GB858487A (en) Process for the production of 4-methyl-4-phenyl-1:3-dioxan
FR1171021A (en) Process for the preparation of condensation products suitable as adjuvants for textiles
GB1121112A (en) Process for the production of dichloro-pyrazines
GB1000198A (en) Process for preparing crystallizable complexes of retinene and certain phenolic materials
GB816855A (en) Improved processes of manufacture of 4-bromo-4-nitrocarbanilide
GB638393A (en) Improvements in and relating to the production of sterols and their addition products from material containing sterols
GB1001712A (en) A process for the preparation of 2,3-dicyano-5,6-dibromo-benzoquinone and this compound when thus prepared
GB914428A (en) Process for the production of ª-, ª--dichloropropionic acid
GB948755A (en) Unsaturated ketones
GB923738A (en) Novel steroid compounds and processes for the preparation thereof